Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0051 | 0.096 | 0.0264 |
Brugia malayi | Carboxylesterase family protein | 0.0051 | 0.096 | 0.096 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0051 | 0.096 | 0.0264 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0051 | 0.096 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.096 | 0.096 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0051 | 0.096 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0051 | 0.096 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0304 | 1 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0051 | 0.096 | 0.0264 |
Loa Loa (eye worm) | carboxylesterase | 0.0051 | 0.096 | 0.096 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.096 | 0.096 |
Schistosoma mansoni | acetylcholinesterase | 0.0051 | 0.096 | 0.0264 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0304 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.096 | 0.096 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0715 | 0.0715 |
Loa Loa (eye worm) | hypothetical protein | 0.0304 | 1 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0304 | 1 | 1 |
Onchocerca volvulus | 0.0051 | 0.096 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.0051 | 0.096 | 0.096 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.096 | 0.096 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | neuroligin | 0.0051 | 0.096 | 0.0264 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0051 | 0.096 | 0.0264 |
Echinococcus granulosus | carboxylesterase 5A | 0.0304 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0051 | 0.096 | 0.096 |
Loa Loa (eye worm) | hypothetical protein | 0.0304 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0 | 0.5 |
Onchocerca volvulus | 0.0051 | 0.096 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.096 | 0.096 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0 | 0.5 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0051 | 0.096 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.096 | 0.096 |
Onchocerca volvulus | 0.0051 | 0.096 | 0.5 | |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0051 | 0.096 | 0.5 |
Onchocerca volvulus | 0.0051 | 0.096 | 0.5 | |
Echinococcus granulosus | neuroligin | 0.0051 | 0.096 | 0.0264 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0715 | 0.0715 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0304 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0051 | 0.096 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0051 | 0.096 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.096 | 0.096 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0051 | 0.096 | 0.0264 |
Brugia malayi | Carboxylesterase family protein | 0.0051 | 0.096 | 0.096 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0051 | 0.096 | 0.0264 |
Schistosoma mansoni | gliotactin | 0.0051 | 0.096 | 0.0264 |
Loa Loa (eye worm) | carboxylesterase | 0.0304 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0304 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0304 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0051 | 0.096 | 0.096 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0051 | 0.096 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0051 | 0.096 | 0.0264 |
Echinococcus multilocularis | acetylcholinesterase | 0.0304 | 1 | 1 |
Onchocerca volvulus | 0.0051 | 0.096 | 0.5 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0051 | 0.096 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0051 | 0.096 | 0.096 |
Echinococcus multilocularis | acetylcholinesterase | 0.0304 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0051 | 0.096 | 0.0264 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.