Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 0.2804 | 0.5 |
Entamoeba histolytica | recQ family DNA helicase | 0.001 | 0.0107 | 0.0381 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0107 | 0.000000002293 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.4788 | 0.4732 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0019 | 0.2804 | 0.1717 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0778 | 0.0679 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.2804 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0915 | 0.0817 |
Schistosoma mansoni | DNA helicase recq1 | 0.0019 | 0.2804 | 0.2804 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 1 | 1 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0019 | 0.2804 | 0.5 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0019 | 0.2804 | 0.2726 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.4788 | 0.4263 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0019 | 0.2804 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.4788 | 0.4263 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.001 | 0.0107 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 1 | 1 |
Schistosoma mansoni | lamin | 0.0026 | 0.4788 | 0.4788 |
Treponema pallidum | ATP-dependent DNA helicase | 0.001 | 0.0107 | 0.5 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.2804 | 0.1717 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.2804 | 0.2726 |
Onchocerca volvulus | 0.0026 | 0.4788 | 0.5 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 1 | 1 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0019 | 0.2804 | 0.5 |
Echinococcus multilocularis | musashi | 0.0026 | 0.4788 | 0.4263 |
Echinococcus granulosus | bloom syndrome protein | 0.0019 | 0.2804 | 0.2079 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.001 | 0.0107 | 0.0107 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 0.2804 | 0.5 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 0.2804 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0778 | 0.0679 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0107 | 0.0381 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.2804 | 0.1717 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.1313 | 0.1219 |
Echinococcus multilocularis | bloom syndrome protein | 0.0019 | 0.2804 | 0.2079 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0019 | 0.2804 | 0.5 |
Schistosoma mansoni | lamin | 0.0026 | 0.4788 | 0.4788 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.4788 | 0.4263 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.4652 | 0.4594 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0019 | 0.2804 | 0.2079 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0019 | 0.2804 | 0.2079 |
Onchocerca volvulus | 0.0026 | 0.4788 | 0.5 | |
Echinococcus granulosus | lamin | 0.0026 | 0.4788 | 0.4263 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0019 | 0.2804 | 0.2079 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.4788 | 0.4732 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 1 | 1 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0019 | 0.2804 | 0.2079 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0019 | 0.2804 | 0.5 |
Entamoeba histolytica | recQ family helicase, putative | 0.0019 | 0.2804 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.4788 | 0.4788 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 1 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.4788 | 0.4001 |
Echinococcus multilocularis | lamin | 0.0026 | 0.4788 | 0.4263 |
Loa Loa (eye worm) | RecQ helicase | 0.0019 | 0.2804 | 0.2726 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.4788 | 0.4001 |
Schistosoma mansoni | DNA helicase recq5 | 0.0019 | 0.2804 | 0.2804 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.4788 | 0.4732 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0019 | 0.2804 | 0.5 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.2804 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.