Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0416 | 0.128 | 0.1501 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1778 | 0.8131 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0416 | 0.128 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.2068 | 0.9589 | 0.9528 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.123 | 0.5371 | 0.6577 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0416 | 0.128 | 0.1501 |
Onchocerca volvulus | 0.1228 | 0.5363 | 0.5331 | |
Giardia lamblia | Ceramide glucosyltransferase | 0.0975 | 0.4089 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1778 | 0.8131 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0416 | 0.128 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0416 | 0.128 | 0.1501 |
Schistosoma mansoni | alpha-glucosidase | 0.1828 | 0.8378 | 0.8378 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.1167 | 0.5055 | 0.5021 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0416 | 0.128 | 0.1501 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1674 | 0.7606 | 0.7606 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1778 | 0.8131 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.2068 | 0.9589 | 0.9586 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.1674 | 0.7606 | 0.7255 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0416 | 0.128 | 0.1219 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1778 | 0.8131 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.123 | 0.5371 | 0.6577 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0416 | 0.128 | 0.1501 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0416 | 0.128 | 0.1501 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.1778 | 0.8131 | 0.8118 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.2068 | 0.9589 | 0.9586 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1778 | 0.8131 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.1828 | 0.8378 | 0.8378 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0416 | 0.128 | 1 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.215 | 1 | 1 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.215 | 1 | 1 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.215 | 1 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0416 | 0.128 | 0.1501 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.2068 | 0.9589 | 0.9528 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0416 | 0.128 | 1 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1674 | 0.7606 | 0.7606 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0416 | 0.128 | 0.1219 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.1674 | 0.7606 | 0.7255 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.1778 | 0.8131 | 0.8118 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0416 | 0.128 | 0.1501 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.1674 | 0.7606 | 0.7255 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.215 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.113 | 0.487 | 0.4834 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.215 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0416 | 0.128 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0416 | 0.128 | 0.1501 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1778 | 0.8131 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Trypanosoma brucei | glucosidase, putative | 0.0416 | 0.128 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0416 | 0.128 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.2068 | 0.9589 | 0.9528 |
Echinococcus granulosus | bile acid beta glucosidase | 0.1674 | 0.7606 | 0.7255 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.215 | 1 | 1 |
Schistosoma mansoni | alpha glucosidase | 0.0416 | 0.128 | 0.128 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.