Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.1751 | 1 | 1 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.1751 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1623 | 0.9188 | 1 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.1751 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1623 | 0.9188 | 1 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0274 | 0.0625 | 0.0465 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.1446 | 0.8068 | 0.8035 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1623 | 0.9188 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0274 | 0.0625 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1122 | 0.6008 | 0.6287 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.1446 | 0.8068 | 0.8035 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.1751 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0274 | 0.0625 | 0.0465 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0274 | 0.0625 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1446 | 0.8068 | 0.8035 |
Schistosoma mansoni | alpha glucosidase | 0.0274 | 0.0625 | 0.0625 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.1308 | 0.7188 | 0.714 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1623 | 0.9188 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.1751 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0883 | 0.4489 | 0.4395 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.1308 | 0.7188 | 0.714 |
Schistosoma mansoni | alpha-glucosidase | 0.1296 | 0.7116 | 0.7116 |
Echinococcus granulosus | bile acid beta glucosidase | 0.1308 | 0.7188 | 0.714 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0274 | 0.0625 | 0.5 |
Trypanosoma brucei | glucosidase, putative | 0.0274 | 0.0625 | 0.5 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.1751 | 1 | 1 |
Onchocerca volvulus | 0.0871 | 0.4415 | 0.432 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Schistosoma mansoni | peroxidasin | 0.0202 | 0.0168 | 0.0168 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1308 | 0.7188 | 0.7188 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0794 | 0.3923 | 0.5 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.1308 | 0.7188 | 0.714 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0274 | 0.0625 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1623 | 0.9188 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1122 | 0.6008 | 0.6287 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0274 | 0.0625 | 0.0465 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.1446 | 0.8068 | 0.8035 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1308 | 0.7188 | 0.7188 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1623 | 0.9188 | 1 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.1065 | 0.5644 | 0.557 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1446 | 0.8068 | 0.8035 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0274 | 0.0625 | 0.5 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0274 | 0.0625 | 0.5 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.1623 | 0.9188 | 0.9174 |
Schistosoma mansoni | alpha-glucosidase | 0.1296 | 0.7116 | 0.7116 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.1623 | 0.9188 | 0.9174 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Schistosoma mansoni | peroxidasin | 0.0202 | 0.0168 | 0.0168 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0274 | 0.0625 | 0.0465 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.