Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | animal heme peroxidase | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0162 | 0.0169 | 0.0226 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0162 | 0.0169 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.088 | 0.8678 | 0.8655 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0779 | 0.7479 | 1 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.0628 | 0.5688 | 0.5688 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Schistosoma mansoni | peroxidasin | 0.0168 | 0.0239 | 0.0071 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0162 | 0.0169 | 0.0169 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0162 | 0.0169 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0168 | 0.0239 | 0.0239 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0162 | 0.0169 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0538 | 0.4631 | 0.6192 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0162 | 0.0169 | 0.0226 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0449 | 0.3575 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0162 | 0.0169 | 0.0226 |
Echinococcus multilocularis | peroxidasin | 0.0168 | 0.0239 | 0.0239 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0162 | 0.0169 | 0.0169 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0628 | 0.5688 | 0.5613 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0628 | 0.5688 | 0.5613 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0779 | 0.7479 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0511 | 0.4304 | 0.4165 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0991 | 1 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0168 | 0.0239 | 0.0239 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.0628 | 0.5688 | 0.5688 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0957 | 0.9598 | 0.9598 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0779 | 0.7479 | 0.7479 |
Brugia malayi | Animal haem peroxidase family protein | 0.0168 | 0.0239 | 0.0239 |
Echinococcus granulosus | peroxidasin | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0168 | 0.0239 | 0.0239 |
Schistosoma mansoni | hypothetical protein | 0.019 | 0.0501 | 0.0337 |
Schistosoma mansoni | alpha-glucosidase | 0.088 | 0.8678 | 0.8655 |
Brugia malayi | Animal haem peroxidase family protein | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0162 | 0.0169 | 0.0226 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.0991 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0162 | 0.0169 | 0.0226 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0779 | 0.7479 | 1 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.0628 | 0.5688 | 0.5688 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0957 | 0.9598 | 0.9598 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0779 | 0.7479 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0162 | 0.0169 | 0.0226 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0162 | 0.0169 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0957 | 0.9598 | 0.9598 |
Onchocerca volvulus | 0.0591 | 0.5256 | 0.514 | |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Trypanosoma brucei | glucosidase, putative | 0.0162 | 0.0169 | 0.5 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0162 | 0.0169 | 0.0169 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0162 | 0.0169 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0779 | 0.7479 | 0.7479 |
Loa Loa (eye worm) | hypothetical protein | 0.0424 | 0.327 | 0.327 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.0991 | 1 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0162 | 0.0169 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Echinococcus granulosus | bile acid beta glucosidase | 0.0628 | 0.5688 | 0.5688 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0162 | 0.0169 | 0.0226 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Brugia malayi | Animal haem peroxidase family protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0162 | 0.0169 | 0.0226 |
Schistosoma mansoni | peroxidasin | 0.0168 | 0.0239 | 0.0071 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.0991 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0162 | 0.0169 | 0.0169 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0162 | 0.0169 | 0.0226 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0779 | 0.7479 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0538 | 0.4631 | 0.6192 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0779 | 0.7479 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0957 | 0.9598 | 0.9598 |
Brugia malayi | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0957 | 0.9598 | 0.9598 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.0991 | 1 | 1 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0991 | 1 | 1 |
Brugia malayi | Peroxidasin | 0.0168 | 0.0239 | 0.0239 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.