TDR Targets

Basic information

Technical information

TDR Targets ID: 807523
Name: 5,5-dimethyl-2-(2,5,9-trimethyldeca-3,4,8-tri en-2-yl)-1,3-dioxane
MW: 292.456 | Formula: C19H32O2
H donors: 0 H acceptors: 0 LogP: 5.35 Rotable bonds: 5
Rule of 5 violations (Lipinski): 1
SMILES: CC(=CCCC(=C=CC(C1OCC(CO1)(C)C)(C)C)C)C
InChi: 1S/C19H32O2/c1-15(2)9-8-10-16(3)11-12-19(6,7)17-20-13-18(4,5)14-21-17/h9,12,17H,8,10,13-14H2,1-7H3
InChiKey: USEUSIFBJPHRNL-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

5,5-dimethyl-2-(1,1,4,8-tetramethylnona-2,3,7-trienyl)-1,3-dioxane
ZINC02904517
CBMicro_009129
BIM-0008985.P001
STOCK1N-03623

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	putative neuropeptide receptor NPR1	0.0029	0.1672	0.1645
Echinococcus multilocularis	neuropeptide receptor A26	0.0029	0.1672	0.1672
Brugia malayi	G-protein coupled receptor	0.0029	0.1672	0.1645
Echinococcus granulosus	PHD finger protein rhinoceros	0.0025	0.1139	0.1139
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.1672	0.1867
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.1672	0.1867
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0029	0.1672	0.1672
Echinococcus multilocularis	sex peptide receptor	0.0029	0.1672	0.1672
Onchocerca volvulus		0.0029	0.1672	1
Onchocerca volvulus		0.0029	0.1672	1
Schistosoma mansoni	amine GPCR	0.0029	0.1672	0.1867
Echinococcus multilocularis	neuropeptide s receptor	0.0029	0.1672	0.1672
Echinococcus granulosus	g protein coupled receptor	0.0029	0.1672	0.1672
Onchocerca volvulus		0.0029	0.1672	1
Echinococcus granulosus	biogenic amine 5HT receptor	0.0029	0.1672	0.1672
Echinococcus multilocularis	g-protein coupled receptor	0.0029	0.1672	0.1672
Onchocerca volvulus		0.0029	0.1672	1
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus granulosus	neuropeptide receptor	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus multilocularis	orexin receptor type 2	0.0029	0.1672	0.1672
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0029	0.1672	0.1867
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.1672	0.1867
Echinococcus multilocularis	dro:myosuppressin receptor	0.0029	0.1672	0.1672
Echinococcus multilocularis	serotonin receptor	0.0029	0.1672	0.1672
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0029	0.1672	0.1645
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0029	0.1672	0.1672
Echinococcus multilocularis	neuropeptide receptor	0.0029	0.1672	0.1672
Brugia malayi	hypothetical protein	0.0029	0.1672	0.1645
Onchocerca volvulus		0.0029	0.1672	1
Plasmodium vivax	hypothetical protein, conserved	0.0025	0.1139	0.5
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Onchocerca volvulus		0.0029	0.1672	1
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.1672	0.1867
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Schistosoma mansoni	hypothetical protein	0.0029	0.1672	0.1867
Echinococcus multilocularis	somatostatin receptor	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0025	0.1139	0.2359
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0029	0.1672	0.1867
Echinococcus granulosus	somatostatin receptor	0.0029	0.1672	0.1672
Echinococcus granulosus	neuropeptide receptor	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0029	0.1672	0.1645
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Loa Loa (eye worm)	G-protein coupled receptor	0.0029	0.1672	0.3673
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0029	0.1672	0.1672
Brugia malayi	neuropeptide F receptor	0.0029	0.1672	0.1645
Schistosoma mansoni	neuropeptide receptor	0.0029	0.1672	0.1867
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Brugia malayi	Serotonin receptor	0.0029	0.1672	0.1645
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0029	0.1672	0.1672
Schistosoma mansoni	growth hormone secretagogue receptor	0.0029	0.1672	0.1867
Brugia malayi	G protein-coupled receptor	0.0029	0.1672	0.1645
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0029	0.1672	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Onchocerca volvulus		0.0029	0.1672	1
Onchocerca volvulus		0.0029	0.1672	1
Brugia malayi	Dopamine receptor protein 1	0.0029	0.1672	0.1645
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0029	0.1672	0.1645
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus granulosus	7TM GPCR rhodopsin	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Schistosoma mansoni	opsin-like receptor	0.0029	0.1672	0.1867
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0029	0.1672	0.1867
Echinococcus granulosus	neuropeptide FF receptor 2	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0029	0.1672	0.1672
Schistosoma mansoni	amine GPCR	0.0029	0.1672	0.1867
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.1672	0.1867
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Schistosoma mansoni	opsin-like receptor	0.0029	0.1672	0.1867
Loa Loa (eye worm)	melatonin receptor type 1A	0.0029	0.1672	0.3673
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus granulosus	neuropeptide s receptor	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0029	0.1672	0.3673
Schistosoma mansoni	opsin-like receptor	0.0029	0.1672	0.1867
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus granulosus	g protein coupled receptor	0.0029	0.1672	0.1672
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0029	0.1672	0.3673
Schistosoma mansoni	neuropeptide receptor	0.0029	0.1672	0.1867
Brugia malayi	hypothetical protein	0.0029	0.1672	0.1645
Echinococcus multilocularis	PHD finger protein rhinoceros	0.0025	0.1139	0.1139
Echinococcus granulosus	G protein coupled receptor 139	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0029	0.1672	0.1867
Brugia malayi	Melatonin receptor type 1A	0.0029	0.1672	0.1645
Giardia lamblia	PHD finger protein 15	0.0025	0.1139	0.5
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Schistosoma mansoni	hypothetical protein	0.0029	0.1672	0.1867
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0029	0.1672	0.1672
Onchocerca volvulus		0.0029	0.1672	1
Schistosoma mansoni	neuropeptide F-like receptor	0.0029	0.1672	0.1867
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0029	0.1672	0.1672
Brugia malayi	neuropeptide F receptor	0.0029	0.1672	0.1645
Echinococcus multilocularis	neuropeptides capa receptor	0.0029	0.1672	0.1672
Echinococcus granulosus	orexin receptor type 2	0.0029	0.1672	0.1672
Brugia malayi	PHD-finger family protein	0.0025	0.1139	0.1056
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0017	0.0182	0.0182
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0029	0.1672	0.1867
Echinococcus granulosus	7tm_1 domain containing protein	0.0029	0.1672	0.1672
Brugia malayi	larval opioid receptor	0.0029	0.1672	0.1645
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0029	0.1672	0.1867
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0029	0.1672	0.1867
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Schistosoma mansoni	amine GPCR	0.0029	0.1672	0.1867
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus multilocularis	neuropeptides capa receptor	0.0029	0.1672	0.1672
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.1672	0.1867
Schistosoma mansoni	neuropeptide receptor	0.0029	0.1672	0.1867
Echinococcus granulosus	fmrfamide receptor	0.0029	0.1672	0.1672
Brugia malayi	Bromodomain containing protein	0.0093	0.9236	1
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0029	0.1672	0.1867
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Loa Loa (eye worm)	hypothetical protein	0.0051	0.4237	1
Plasmodium falciparum	phd finger protein, putative	0.0025	0.1139	0.5
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Schistosoma mansoni	bromodomain-containing nuclear protein 1 brd1	0.009	0.8951	1
Echinococcus granulosus	hypothetical protein	0.0029	0.1672	0.1672
Schistosoma mansoni	biogenic amine receptor	0.0029	0.1672	0.1867
Loa Loa (eye worm)	TYRA-2 protein	0.0029	0.1672	0.3673
Echinococcus granulosus	dro:myosuppressin receptor	0.0029	0.1672	0.1672
Trichomonas vaginalis	conserved hypothetical protein	0.0051	0.4237	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Onchocerca volvulus		0.0029	0.1672	1
Brugia malayi	G-protein coupled receptor	0.0029	0.1672	0.1645
Echinococcus granulosus	serotonin receptor	0.0029	0.1672	0.1672
Brugia malayi	hypothetical protein	0.0029	0.1672	0.1645
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0029	0.1672	0.1867
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0029	0.1672	0.1672
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0029	0.1672	0.1645
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Schistosoma mansoni	histamine h1 receptor	0.0029	0.1672	0.1867
Brugia malayi	hypothetical protein	0.0029	0.1672	0.1645
Brugia malayi	hypothetical protein	0.0029	0.1672	0.1645
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0029	0.1672	1
Onchocerca volvulus		0.0029	0.1672	1
Echinococcus multilocularis	fmrfamide receptor	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Brugia malayi	hypothetical protein	0.0029	0.1672	0.1645
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Brugia malayi	Dopamine receptor	0.0029	0.1672	0.1645
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0029	0.1672	0.1645
Echinococcus multilocularis	G protein coupled receptor 139	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0029	0.1672	0.1672
Brugia malayi	Serotonin receptor	0.0029	0.1672	0.1645
Schistosoma mansoni	hypothetical protein	0.0029	0.1672	0.1867
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0029	0.1672	0.3673
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0029	0.1672	0.1672
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0029	0.1672	0.1672
Toxoplasma gondii	PHD-finger domain-containing protein	0.0025	0.1139	0.5
Loa Loa (eye worm)	neuropeptide F receptor	0.0029	0.1672	0.3673
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.1672	0.1867
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0029	0.1672	0.1867
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0029	0.1672	0.1672
Brugia malayi	G protein-coupled receptor F59B2.13	0.0029	0.1672	0.1645
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0029	0.1672	0.1867
Schistosoma mansoni	neuropeptide F-like receptor	0.0029	0.1672	0.1867
Brugia malayi	Dopamine receptor protein 2	0.0029	0.1672	0.1645
Echinococcus multilocularis	neuropeptide receptor	0.0029	0.1672	0.1672
Brugia malayi	sulfakinin receptor protein	0.0029	0.1672	0.1645
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Echinococcus granulosus	tm gpcr rhodopsin	0.0029	0.1672	0.1672
Echinococcus granulosus	tm gpcr rhodopsin	0.0029	0.1672	0.1672
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0029	0.1672	0.1672
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0029	0.1672	0.1867
Schistosoma mansoni	amine GPCR	0.0029	0.1672	0.1867
Echinococcus granulosus	neuropeptide Y receptor	0.0029	0.1672	0.1672
Onchocerca volvulus		0.0029	0.1672	1
Toxoplasma gondii	PHD-finger domain-containing protein	0.0025	0.1139	0.5
Onchocerca volvulus		0.0029	0.1672	1
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0029	0.1672	0.1672
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Brugia malayi	putative neuropeptide receptor	0.0029	0.1672	0.1645
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus multilocularis	serotonin receptor	0.0029	0.1672	0.1672
Echinococcus granulosus	neuropeptide receptor A26	0.0029	0.1672	0.1672
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0029	0.1672	0.1867
Brugia malayi	hypothetical protein	0.0029	0.1672	0.1645
Onchocerca volvulus		0.0029	0.1672	1
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus granulosus	tm gpcr rhodopsin	0.0029	0.1672	0.1672
Echinococcus multilocularis	neuropeptide Y receptor	0.0029	0.1672	0.1672
Echinococcus granulosus	sex peptide receptor	0.0029	0.1672	0.1672
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Schistosoma mansoni	neuropeptide receptor	0.0029	0.1672	0.1867
Brugia malayi	hypothetical protein	0.0029	0.1672	0.1645
Loa Loa (eye worm)	PHD-finger family protein	0.0025	0.1139	0.2359
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.1672	0.1867
Brugia malayi	hypothetical protein	0.0029	0.1672	0.1645
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus multilocularis	allatostatin A receptor	0.0029	0.1672	0.1672
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0029	0.1672	0.1672
Echinococcus granulosus	allatostatin A receptor	0.0029	0.1672	0.1672
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0029	0.1672	0.1672
Echinococcus multilocularis	g protein coupled receptor	0.0029	0.1672	0.1672
Schistosoma mansoni	biogenic amine receptor	0.0029	0.1672	0.1867
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.1672	0.1867
Loa Loa (eye worm)	neuropeptide F receptor	0.0029	0.1672	0.3673
Schistosoma mansoni	adenoreceptor	0.0029	0.1672	0.1867
Echinococcus multilocularis	neuropeptide Y receptor	0.0029	0.1672	0.1672
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0029	0.1672	0.1867
Echinococcus multilocularis	g protein coupled receptor	0.0029	0.1672	0.1672
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Schistosoma mansoni	hypothetical protein	0.0029	0.1672	0.1867
Brugia malayi	ORL1-like opioid receptor	0.0029	0.1672	0.1645
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Echinococcus multilocularis	fmrfamide receptor	0.0029	0.1672	0.1672
Schistosoma mansoni	hypothetical protein	0.0025	0.1139	0.1272
Echinococcus granulosus	neuropeptides capa receptor	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus granulosus	neuropeptides capa receptor	0.0029	0.1672	0.1672
Echinococcus multilocularis	peregrin	0.0099	1	1
Schistosoma mansoni	biogenic amine receptor	0.0029	0.1672	0.1867
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0029	0.1672	0.1672
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0029	0.1672	0.3673
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0029	0.1672	0.1672
Echinococcus granulosus	biogenic amine 5HT receptor	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0029	0.1672	0.1672
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0029	0.1672	0.1867
Schistosoma mansoni	amine GPCR	0.0029	0.1672	0.1867
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0029	0.1672	0.1672
Echinococcus granulosus	neuropeptide Y receptor	0.0029	0.1672	0.1672
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0029	0.1672	0.3673
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0017	0.0182	0.0182
Brugia malayi	follicle stimulating hormone receptor	0.0029	0.1672	0.1645
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0029	0.1672	0.1672
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0029	0.1672	0.1645
Onchocerca volvulus		0.0029	0.1672	1
Schistosoma mansoni	myosin xvIII	0.0029	0.1672	0.1867
Schistosoma mansoni	neuropeptide f receptor 76f	0.0029	0.1672	0.1867
Echinococcus granulosus	g protein coupled receptor	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Loa Loa (eye worm)	G-protein coupled receptor	0.0029	0.1672	0.3673
Brugia malayi	hypothetical protein	0.0029	0.1672	0.1645
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0029	0.1672	0.1672
Echinococcus multilocularis	g protein coupled receptor	0.0029	0.1672	0.1672
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0029	0.1672	0.1867
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.1672	0.1672
Brugia malayi	AKH receptor	0.0029	0.1672	0.1645
Onchocerca volvulus		0.0029	0.1672	1
Echinococcus granulosus	g-protein coupled receptor	0.0029	0.1672	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Onchocerca volvulus		0.0029	0.1672	1
Brugia malayi	RE15519p	0.0029	0.1672	0.1645
Brugia malayi	GnHR receptor homolog	0.0029	0.1672	0.1645
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1672	0.3673
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0029	0.1672	0.1672

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 807523