Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | fucosidase alpha L 1 tissue | 0.1188 | 0.9004 | 0.9004 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1299 | 1 | 1 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0448 | 0.2351 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.029 | 0.0929 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.1178 | 0.8908 | 1 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.1188 | 0.9004 | 0.5 |
Schistosoma mansoni | alpha glucosidase | 0.029 | 0.0929 | 0.1043 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.1021 | 0.7504 | 0.7504 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.1188 | 0.9004 | 0.9004 |
Leishmania major | alpha glucosidase II subunit, putative | 0.029 | 0.0929 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.029 | 0.0929 | 0.5 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.029 | 0.0929 | 0.5 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.029 | 0.0929 | 0.0929 |
Onchocerca volvulus | 0.1178 | 0.8908 | 0.5 | |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.1299 | 1 | 1 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0448 | 0.2351 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.029 | 0.0929 | 0.5 |
Schistosoma mansoni | alpha-l-fucosidase | 0.1021 | 0.7504 | 0.8424 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.029 | 0.0929 | 0.0929 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.1299 | 1 | 1 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.029 | 0.0929 | 0.0929 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.029 | 0.0929 | 0.0929 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1299 | 1 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.1178 | 0.8908 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.029 | 0.0929 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.029 | 0.0929 | 0.5 |
Brugia malayi | Alpha-L-fucosidase family protein | 0.1021 | 0.7504 | 0.7504 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.