Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | polo-like protein kinase, putative | 0.2622 | 1 | 0.5 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0223 | 0.0467 | 0.0467 |
Loa Loa (eye worm) | hypothetical protein | 0.0223 | 0.0467 | 0.0467 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0223 | 0.0467 | 0.0467 |
Loa Loa (eye worm) | hypothetical protein | 0.0223 | 0.0467 | 0.0467 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.2622 | 1 | 1 |
Schistosoma mansoni | gliotactin | 0.0223 | 0.0467 | 0.0467 |
Schistosoma mansoni | acetylcholinesterase | 0.0223 | 0.0467 | 0.0467 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.2622 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1321 | 0.4832 | 0.4832 |
Loa Loa (eye worm) | hypothetical protein | 0.0223 | 0.0467 | 0.0467 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0223 | 0.0467 | 0.0467 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0223 | 0.0467 | 0.0467 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0223 | 0.0467 | 0.0467 |
Onchocerca volvulus | 0.0223 | 0.0467 | 0.0467 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.1298 | 0.4738 | 0.4738 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.2622 | 1 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1321 | 0.4832 | 0.4832 |
Onchocerca volvulus | 0.0223 | 0.0467 | 0.0467 | |
Echinococcus granulosus | BC026374 protein S09 family | 0.0223 | 0.0467 | 0.0467 |
Trichomonas vaginalis | CAMK family protein kinase | 0.2622 | 1 | 1 |
Onchocerca volvulus | 0.0223 | 0.0467 | 0.0467 | |
Loa Loa (eye worm) | hypothetical protein | 0.0223 | 0.0467 | 0.0467 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.2622 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0223 | 0.0467 | 0.0467 |
Loa Loa (eye worm) | hypothetical protein | 0.0223 | 0.0467 | 0.0467 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0223 | 0.0467 | 0.0467 |
Trichomonas vaginalis | CAMK family protein kinase | 0.2622 | 1 | 1 |
Schistosoma mansoni | kinase | 0.1332 | 0.4876 | 0.4876 |
Echinococcus granulosus | acetylcholinesterase | 0.1321 | 0.4832 | 0.4832 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1321 | 0.4832 | 0.4832 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.2622 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0223 | 0.0467 | 0.0467 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0223 | 0.0467 | 0.0467 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0223 | 0.0467 | 0.0467 |
Echinococcus granulosus | neuroligin | 0.0223 | 0.0467 | 0.0467 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0223 | 0.0467 | 0.0467 |
Trichomonas vaginalis | CAMK family protein kinase | 0.2622 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0223 | 0.0467 | 0.0467 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.2622 | 1 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.1321 | 0.4832 | 0.4832 |
Brugia malayi | Carboxylesterase family protein | 0.0223 | 0.0467 | 0.0467 |
Echinococcus multilocularis | acetylcholinesterase | 0.1321 | 0.4832 | 0.4832 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1298 | 0.4738 | 0.4738 |
Brugia malayi | Carboxylesterase family protein | 0.1321 | 0.4832 | 0.4832 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0223 | 0.0467 | 0.5 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.2622 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.2622 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0223 | 0.0467 | 0.0467 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1321 | 0.4832 | 0.4832 |
Echinococcus granulosus | acetylcholinesterase | 0.1321 | 0.4832 | 0.4832 |
Loa Loa (eye worm) | hypothetical protein | 0.0223 | 0.0467 | 0.0467 |
Loa Loa (eye worm) | carboxylesterase | 0.0223 | 0.0467 | 0.0467 |
Brugia malayi | Carboxylesterase family protein | 0.0223 | 0.0467 | 0.0467 |
Onchocerca volvulus | 0.0223 | 0.0467 | 0.0467 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.2622 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.1321 | 0.4832 | 0.4832 |
Onchocerca volvulus | 0.0223 | 0.0467 | 0.0467 | |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0223 | 0.0467 | 0.5 |
Trypanosoma brucei | polo-like protein kinase | 0.2622 | 1 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2622 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.1321 | 0.4832 | 0.4832 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0106 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.1321 | 0.4832 | 0.4832 |
Brugia malayi | Carboxylesterase family protein | 0.0223 | 0.0467 | 0.0467 |
Loa Loa (eye worm) | hypothetical protein | 0.0223 | 0.0467 | 0.0467 |
Trichomonas vaginalis | CAMK family protein kinase | 0.2622 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1321 | 0.4832 | 0.4832 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0223 | 0.0467 | 0.0467 |
Giardia lamblia | Kinase, PLK | 0.2622 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0223 | 0.0467 | 0.0467 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0223 | 0.0467 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.2622 | 1 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0223 | 0.0467 | 0.0467 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0223 | 0.0467 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.