Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | glycogen debranching enzyme, putative | 0.0147 | 0.0159 | 0.3084 |
Trichomonas vaginalis | glycogen debranching enzyme, putative | 0.0147 | 0.0159 | 0.0771 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0187 | 0.0516 | 1 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.0821 | 0.618 | 0.6118 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0187 | 0.0516 | 0.0363 |
Brugia malayi | Alpha-L-fucosidase family protein | 0.0821 | 0.618 | 0.618 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.1248 | 1 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0187 | 0.0516 | 0.25 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0187 | 0.0516 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0187 | 0.0516 | 0.25 |
Echinococcus granulosus | fucosidase alpha L 1 tissue | 0.0821 | 0.618 | 0.6118 |
Trypanosoma brucei | glucosidase, putative | 0.0187 | 0.0516 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.1191 | 0.9484 | 1 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.0821 | 0.618 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0187 | 0.0516 | 0.0516 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.0821 | 0.618 | 0.618 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0187 | 0.0516 | 0.0363 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1248 | 1 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0187 | 0.0516 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0187 | 0.0516 | 0.25 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0187 | 0.0516 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0187 | 0.0516 | 1 |
Schistosoma mansoni | alpha-l-fucosidase | 0.0821 | 0.618 | 0.6315 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1248 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0187 | 0.0516 | 1 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0187 | 0.0516 | 0.25 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0187 | 0.0516 | 0.25 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0187 | 0.0516 | 0.25 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.036 | 0.2065 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0187 | 0.0516 | 0.25 |
Schistosoma mansoni | hypothetical protein | 0.0189 | 0.0534 | 0.0019 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0187 | 0.0516 | 0.25 |
Onchocerca volvulus | 0.0902 | 0.6907 | 1 | |
Brugia malayi | Amylo-alpha-1,6-glucosidase family protein | 0.0147 | 0.0159 | 0.0159 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.1248 | 1 | 1 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.036 | 0.2065 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0187 | 0.0516 | 0.25 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0159 | 0.0159 |
Trichomonas vaginalis | glycogen debranching enzyme, putative | 0.0147 | 0.0159 | 0.0771 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0187 | 0.0516 | 0.0516 |
Schistosoma mansoni | alpha-glucosidase | 0.1191 | 0.9484 | 1 |
Giardia lamblia | 4-alpha-glucanotransferase, amylo-alpha-1,6-glucosidase | 0.0147 | 0.0159 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.