Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | BC026374 protein S09 family | 0.0438 | 0.1622 | 0.1622 |
Echinococcus granulosus | PDZ and LIM domain protein Zasp | 0.0022 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0438 | 0.1622 | 0.5 |
Echinococcus multilocularis | neuroligin | 0.0438 | 0.1622 | 0.1622 |
Echinococcus granulosus | dual specificity testis-specific protein kinase | 0.1605 | 0.6166 | 0.6166 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Echinococcus multilocularis | microtubule associated serine:threonine protein | 0.0021 | 0.0001 | 0.0001 |
Echinococcus granulosus | peripheral plasma membrane protein CASK | 0.0021 | 0.0001 | 0.0001 |
Schistosoma mansoni | protein kinase | 0.1605 | 0.6166 | 0.6166 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0438 | 0.1622 | 0.5 |
Schistosoma mansoni | gliotactin | 0.0438 | 0.1622 | 0.1622 |
Echinococcus multilocularis | PDZ and LIM domain protein Zasp | 0.0022 | 0.0003 | 0.0003 |
Echinococcus granulosus | PKC activated phosphatase 1 inhibitor | 0.003 | 0.0036 | 0.0036 |
Brugia malayi | Carboxylesterase family protein | 0.0438 | 0.1622 | 0.1622 |
Echinococcus multilocularis | acetylcholinesterase | 0.259 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.259 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Brugia malayi | Carboxylesterase family protein | 0.0438 | 0.1622 | 0.1622 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0438 | 0.1622 | 0.5 |
Echinococcus multilocularis | peripheral plasma membrane protein CASK | 0.0021 | 0.0001 | 0.0001 |
Echinococcus multilocularis | PDZ and LIM domain protein Zasp | 0.0022 | 0.0003 | 0.0003 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.259 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Loa Loa (eye worm) | AGC/MAST/MAST protein kinase | 0.0021 | 0.0001 | 0.0001 |
Echinococcus multilocularis | dual specificity testis specific protein kinase | 0.1605 | 0.6166 | 0.6166 |
Brugia malayi | hypothetical protein | 0.003 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0036 | 0.0036 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0438 | 0.1622 | 0.1622 |
Loa Loa (eye worm) | carboxylesterase | 0.0438 | 0.1622 | 0.1622 |
Schistosoma mansoni | MAGUK homolog | 0.0021 | 0.0001 | 0.0001 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0438 | 0.1622 | 0.1622 |
Echinococcus multilocularis | acetylcholinesterase | 0.259 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0438 | 0.1622 | 0.1622 |
Brugia malayi | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Schistosoma mansoni | protein kinase | 0.1605 | 0.6166 | 0.6166 |
Echinococcus granulosus | Microtubule-associated serine/threonine-protein kinase | 0.0021 | 0.0001 | 0.0001 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Brugia malayi | Carboxylesterase family protein | 0.259 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0438 | 0.1622 | 0.1622 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.259 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Onchocerca volvulus | 0.0438 | 0.1622 | 1 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0438 | 0.1622 | 0.5 |
Schistosoma mansoni | lim domain | 0.0022 | 0.0003 | 0.0003 |
Echinococcus granulosus | PDZ and LIM domain protein Zasp | 0.0022 | 0.0003 | 0.0003 |
Schistosoma mansoni | pdz and lim domain protein | 0.0022 | 0.0003 | 0.0003 |
Schistosoma mansoni | acetylcholinesterase | 0.0438 | 0.1622 | 0.1622 |
Echinococcus multilocularis | PKC activated phosphatase 1 inhibitor | 0.003 | 0.0036 | 0.0036 |
Echinococcus multilocularis | carboxylesterase 5A | 0.259 | 1 | 1 |
Onchocerca volvulus | 0.0438 | 0.1622 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Echinococcus granulosus | carboxylesterase 5A | 0.259 | 1 | 1 |
Onchocerca volvulus | 0.003 | 0.0036 | 0.022 | |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Chlamydia trachomatis | tail-specific protease | 0.0021 | 0 | 0.5 |
Onchocerca volvulus | 0.0438 | 0.1622 | 1 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0438 | 0.1622 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.259 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Echinococcus granulosus | neuroligin | 0.0438 | 0.1622 | 0.1622 |
Brugia malayi | Carboxylesterase family protein | 0.0438 | 0.1622 | 0.1622 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Onchocerca volvulus | 0.0438 | 0.1622 | 1 | |
Echinococcus granulosus | acetylcholinesterase | 0.259 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.259 | 1 | 1 |
Onchocerca volvulus | 0.0021 | 0.0001 | 0.0005 | |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0438 | 0.1622 | 0.5 |
Onchocerca volvulus | 0.0438 | 0.1622 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.259 | 1 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0438 | 0.1622 | 0.1622 |
Schistosoma mansoni | protein phosphatase 1 inhibitor potentiated by protein kinase C | 0.003 | 0.0036 | 0.0036 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.