Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0267 | 0.0267 |
Echinococcus multilocularis | acetylcholinesterase | 0.0231 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0039 | 0.0267 | 0.0267 |
Brugia malayi | Carboxylesterase family protein | 0.0039 | 0.0267 | 0.0267 |
Echinococcus granulosus | acetylcholinesterase | 0.0231 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0267 | 0.0267 |
Echinococcus granulosus | acetylcholinesterase | 0.0231 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 1 | 1 |
Onchocerca volvulus | 0.0039 | 0.0267 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.0231 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0039 | 0.0267 | 0.5 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0039 | 0.0267 | 0.0267 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0039 | 0.0267 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0039 | 0.0267 | 0.0267 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0039 | 0.0267 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0039 | 0.0267 | 0.0267 |
Echinococcus granulosus | carboxylesterase 5A | 0.0231 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0039 | 0.0267 | 0.0267 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0039 | 0.0267 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | carboxylesterase | 0.0039 | 0.0267 | 0.0267 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0034 | 0 | 0.5 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0039 | 0.0267 | 0.0267 |
Onchocerca volvulus | 0.0039 | 0.0267 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0267 | 0.0267 |
Onchocerca volvulus | 0.0039 | 0.0267 | 0.5 | |
Schistosoma mansoni | acetylcholinesterase | 0.0039 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | carboxylesterase | 0.0039 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0267 | 0.0267 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0034 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0231 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0039 | 0.0267 | 0.0267 |
Echinococcus multilocularis | acetylcholinesterase | 0.0231 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0039 | 0.0267 | 0.0267 |
Echinococcus multilocularis | neuroligin | 0.0039 | 0.0267 | 0.0267 |
Onchocerca volvulus | 0.0039 | 0.0267 | 0.5 | |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0034 | 0 | 0.5 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0039 | 0.0267 | 0.5 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0267 | 0.0267 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0034 | 0 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0231 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0231 | 1 | 1 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0034 | 0 | 0.5 |
Onchocerca volvulus | 0.0039 | 0.0267 | 0.5 | |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0034 | 0 | 0.5 |
Echinococcus granulosus | neuroligin | 0.0039 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0267 | 0.0267 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0039 | 0.0267 | 0.0267 |
Brugia malayi | Carboxylesterase family protein | 0.0231 | 1 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0039 | 0.0267 | 0.0267 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0039 | 0.0267 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0039 | 0.0267 | 0.0267 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0039 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0267 | 0.0267 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0039 | 0.0267 | 0.0267 |
Schistosoma mansoni | gliotactin | 0.0039 | 0.0267 | 0.0267 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0039 | 0.0267 | 0.0267 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.