Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Carboxylesterase family protein | 0.0027 | 0.057 | 0.057 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0022 | 0.021 | 0.021 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0057 | 0.2781 | 0.2781 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0027 | 0.057 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0027 | 0.057 | 0.0368 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0158 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0027 | 0.057 | 0.057 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0027 | 0.057 | 0.0368 |
Loa Loa (eye worm) | carboxylesterase | 0.0158 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0027 | 0.057 | 0.0368 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0027 | 0.057 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.074 | 0.0541 |
Brugia malayi | Carboxylesterase family protein | 0.0027 | 0.057 | 0.057 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0027 | 0.057 | 0.0368 |
Loa Loa (eye worm) | carboxylesterase | 0.0027 | 0.057 | 0.0368 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0027 | 0.057 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.074 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 0.2781 | 0.2781 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0022 | 0.021 | 0.5 |
Onchocerca volvulus | 0.0027 | 0.057 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.057 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.2781 | 0.2626 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.057 | 0.0368 |
Onchocerca volvulus | 0.0027 | 0.057 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0158 | 1 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0027 | 0.057 | 0.0368 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0022 | 0.021 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.074 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0158 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.074 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.1474 | 0.1474 |
Echinococcus multilocularis | acetylcholinesterase | 0.0158 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0027 | 0.057 | 0.057 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.057 | 0.0368 |
Echinococcus multilocularis | acetylcholinesterase | 0.0158 | 1 | 1 |
Onchocerca volvulus | 0.0027 | 0.057 | 0.5 | |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0022 | 0.021 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0027 | 0.057 | 0.057 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 0.2781 | 0.2626 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0027 | 0.057 | 0.0368 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.074 | 1 |
Schistosoma mansoni | gliotactin | 0.0027 | 0.057 | 0.0368 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.074 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.074 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0022 | 0.021 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.057 | 0.0368 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.1474 | 0.1292 |
Schistosoma mansoni | acetylcholinesterase | 0.0027 | 0.057 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.057 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.057 | 0.0368 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0027 | 0.057 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0027 | 0.057 | 0.0368 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0027 | 0.057 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0027 | 0.057 | 0.0368 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.074 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0158 | 1 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0027 | 0.057 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.057 | 0.0368 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.074 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0158 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0158 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 1 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0027 | 0.057 | 0.0368 |
Onchocerca volvulus | 0.0027 | 0.057 | 0.5 | |
Onchocerca volvulus | 0.0027 | 0.057 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0027 | 0.057 | 0.0368 |
Brugia malayi | hypothetical protein | 0.0029 | 0.074 | 0.074 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0027 | 0.057 | 0.0368 |
Echinococcus granulosus | carboxylesterase 5A | 0.0158 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0027 | 0.057 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1474 | 0.1292 |
Echinococcus granulosus | neuroligin | 0.0027 | 0.057 | 0.0368 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0027 | 0.057 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.