Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0757 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0757 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0757 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0757 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0335 | 0.2657 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0757 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0289 | 0.1841 | 0.6929 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0335 | 0.2657 | 0.2657 |
Onchocerca volvulus | 0.0335 | 0.2657 | 1 | |
Onchocerca volvulus | Cathepsin F homolog | 0.0335 | 0.2657 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0335 | 0.2657 | 0.2657 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0335 | 0.2657 | 0.1979 |
Brugia malayi | Cathepsin L-like precursor | 0.0231 | 0.0846 | 0.0846 |
Leishmania major | cysteine peptidase A (CPA) | 0.0335 | 0.2657 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0335 | 0.2657 | 0.2657 |
Entamoeba histolytica | cysteine protease, putative | 0.0335 | 0.2657 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0231 | 0.0846 | 0.0846 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Echinococcus granulosus | cathepsin b | 0.0757 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0757 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0335 | 0.2657 | 0.2657 |
Echinococcus multilocularis | cathepsin b | 0.0757 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0335 | 0.2657 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0335 | 0.2657 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0335 | 0.2657 | 0.2657 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0335 | 0.2657 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0335 | 0.2657 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0335 | 0.2657 | 0.1979 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0289 | 0.1841 | 0.1841 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0757 | 1 | 1 |
Onchocerca volvulus | 0.0335 | 0.2657 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0335 | 0.2657 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0289 | 0.1841 | 0.1841 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0335 | 0.2657 | 0.1979 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0335 | 0.2657 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0335 | 0.2657 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0335 | 0.2657 | 0.2657 |
Giardia lamblia | Cathepsin B precursor | 0.0289 | 0.1841 | 0.5 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0335 | 0.2657 | 0.2657 |
Leishmania major | cathepsin L-like protease | 0.0335 | 0.2657 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0289 | 0.1841 | 0.5 |
Echinococcus multilocularis | cysteine protease | 0.0335 | 0.2657 | 0.2657 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0231 | 0.0846 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0335 | 0.2657 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0335 | 0.2657 | 0.2657 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0335 | 0.2657 | 0.2657 |
Leishmania major | cathepsin L-like protease | 0.0335 | 0.2657 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0335 | 0.2657 | 0.2657 |
Onchocerca volvulus | 0.0335 | 0.2657 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0335 | 0.2657 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0335 | 0.2657 | 0.2657 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0335 | 0.2657 | 0.2657 |
Leishmania major | cathepsin L-like protease | 0.0335 | 0.2657 | 1 |
Leishmania major | cathepsin L-like protease | 0.0335 | 0.2657 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0335 | 0.2657 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0289 | 0.1841 | 0.1088 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0231 | 0.0846 | 0.3182 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0335 | 0.2657 | 0.2657 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0335 | 0.2657 | 1 |
Leishmania major | cathepsin L-like protease | 0.0335 | 0.2657 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0289 | 0.1841 | 0.6929 |
Onchocerca volvulus | 0.0335 | 0.2657 | 1 | |
Onchocerca volvulus | 0.0335 | 0.2657 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0335 | 0.2657 | 0.1979 |
Brugia malayi | cathepsin L-like precursor | 0.0231 | 0.0846 | 0.0846 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0335 | 0.2657 | 0.2657 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0335 | 0.2657 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0231 | 0.0846 | 0.0846 |
Brugia malayi | Cathepsin L-like precursor | 0.0335 | 0.2657 | 0.2657 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0335 | 0.2657 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0335 | 0.2657 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0757 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0289 | 0.1841 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0335 | 0.2657 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0335 | 0.2657 | 0.2657 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0335 | 0.2657 | 0.2657 |
Loa Loa (eye worm) | cysteine protease | 0.0335 | 0.2657 | 0.1979 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0335 | 0.2657 | 1 |
Plasmodium vivax | vivapain-2 | 0.0335 | 0.2657 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0335 | 0.2657 | 0.2657 |
Brugia malayi | Cathepsin L-like precursor | 0.0335 | 0.2657 | 0.2657 |
Leishmania major | cathepsin L-like protease | 0.0335 | 0.2657 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0335 | 0.2657 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0335 | 0.2657 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0335 | 0.2657 | 1 |
Onchocerca volvulus | 0.0335 | 0.2657 | 1 | |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0335 | 0.2657 | 0.2657 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0231 | 0.0846 | 0.3182 |
Loa Loa (eye worm) | fibroinase | 0.0335 | 0.2657 | 0.1979 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Onchocerca volvulus | 0.0335 | 0.2657 | 1 | |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0231 | 0.0846 | 0.0846 |
Echinococcus granulosus | cathepsin l1 | 0.0231 | 0.0846 | 0.0846 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0335 | 0.2657 | 0.2657 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0231 | 0.0846 | 0.0846 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0335 | 0.2657 | 0.2657 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0335 | 0.2657 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0335 | 0.2657 | 1 |
Leishmania major | cathepsin L-like protease | 0.0335 | 0.2657 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.