Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | protein kinase c iota type | 0.0013 | 0.0399 | 0.042 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0107 | 0.5536 | 0.673 |
Trichomonas vaginalis | AGC family protein kinase | 0.0038 | 0.1783 | 0.3179 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.001 | 0.0239 | 0.0239 |
Echinococcus multilocularis | nervana 2 | 0.0023 | 0.0926 | 0.0974 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0013 | 0.0399 | 0.0399 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0027 | 0.1142 | 0.12 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0571 | 0.0571 |
Entamoeba histolytica | hypothetical protein, conserved | 0.004 | 0.1896 | 0.3383 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0013 | 0.0399 | 0.042 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0571 | 0.0571 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0179 | 0.9512 | 0.9512 |
Schistosoma mansoni | eukaryotic elongation factor 2 kinase (eef-2 kinase) | 0.0139 | 0.7305 | 0.7305 |
Echinococcus granulosus | nervana 2 | 0.0023 | 0.0926 | 0.0974 |
Trichomonas vaginalis | AGC family protein kinase | 0.0038 | 0.1783 | 0.3179 |
Entamoeba histolytica | hypothetical protein, conserved | 0.004 | 0.1896 | 0.3383 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.1896 | 0.3383 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0013 | 0.0399 | 0.042 |
Schistosoma mansoni | cell adhesion molecule | 0.0014 | 0.0425 | 0.0425 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.5536 | 1 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0013 | 0.0399 | 0.0399 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0027 | 0.1142 | 0.1142 |
Trichomonas vaginalis | AGC family protein kinase | 0.0038 | 0.1783 | 0.3179 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0008 | 0.009 | 0.009 |
Trichomonas vaginalis | AGC family protein kinase | 0.0013 | 0.0399 | 0.0663 |
Entamoeba histolytica | elongation factor-2 kinase, putative | 0.004 | 0.1896 | 0.3383 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0239 | 0.0239 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.5536 | 1 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0014 | 0.0425 | 0.0447 |
Entamoeba histolytica | protein kinase, putative | 0.004 | 0.1896 | 0.3383 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0013 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.7305 | 0.7305 |
Entamoeba histolytica | protein kinase, putative | 0.0013 | 0.0399 | 0.0663 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0107 | 0.5536 | 0.5821 |
Brugia malayi | hypothetical protein | 0.001 | 0.0239 | 0.0239 |
Schistosoma mansoni | tyrosine kinase | 0.0007 | 0.0052 | 0.0052 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0024 | 0.1016 | 0.5 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0036 | 0.1657 | 0.1657 |
Echinococcus granulosus | protein kinase C gamma type | 0.0013 | 0.0399 | 0.042 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0425 | 0.0425 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0013 | 0.0399 | 0.0399 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0013 | 0.0399 | 0.0399 |
Trichomonas vaginalis | AGC family protein kinase | 0.0038 | 0.1783 | 0.3179 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0013 | 0.0399 | 0.042 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0013 | 0.0399 | 0.042 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.1896 | 0.3383 |
Echinococcus granulosus | NDR protein kinase | 0.0013 | 0.0399 | 0.042 |
Entamoeba histolytica | protein kinase, putative | 0.0036 | 0.1657 | 0.295 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0013 | 0.0399 | 0.042 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0023 | 0.0926 | 0.0974 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0023 | 0.0926 | 0.0974 |
Onchocerca volvulus | 0.0154 | 0.8139 | 0.8557 | |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0107 | 0.5536 | 0.5536 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0107 | 0.5536 | 0.5536 |
Schistosoma mansoni | nephrin | 0.0013 | 0.0385 | 0.0385 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.1896 | 0.3383 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0024 | 0.1016 | 0.1068 |
Echinococcus multilocularis | nervana 2 | 0.0023 | 0.0926 | 0.0974 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0168 | 0.8948 | 0.8948 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0027 | 0.1142 | 0.12 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0027 | 0.1142 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0399 | 0.0399 |
Trypanosoma brucei | polo-like protein kinase | 0.0107 | 0.5536 | 0.6796 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0023 | 0.0926 | 0.0974 |
Brugia malayi | Fibronectin type III domain containing protein | 0.001 | 0.0239 | 0.0239 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0013 | 0.0399 | 0.042 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0157 | 0.8337 | 0.8765 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0013 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0013 | 0.0399 | 0.0399 |
Brugia malayi | Protein kinase domain containing protein | 0.0013 | 0.0399 | 0.0399 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0168 | 0.8948 | 0.8948 |
Echinococcus granulosus | twitchin | 0.0015 | 0.0475 | 0.0499 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0013 | 0.0399 | 0.0399 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0013 | 0.0399 | 0.042 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0027 | 0.1142 | 0.1142 |
Giardia lamblia | Kinase, PLK | 0.0107 | 0.5536 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0239 | 0.0239 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.1896 | 0.3383 |
Trypanosoma cruzi | Protein kinase B | 0.0027 | 0.1142 | 0.02 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0013 | 0.0399 | 0.042 |
Trichomonas vaginalis | AGC family protein kinase | 0.0013 | 0.0399 | 0.0663 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0107 | 0.5536 | 0.5536 |
Brugia malayi | Hr1 repeat family protein | 0.0013 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0013 | 0.0399 | 0.0399 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0027 | 0.1142 | 0.2012 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.1896 | 0.3383 |
Echinococcus granulosus | neuroglian | 0.0013 | 0.0385 | 0.0405 |
Echinococcus granulosus | defective proboscis extension response | 0.001 | 0.0239 | 0.0251 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0024 | 0.1016 | 0.1068 |
Trypanosoma brucei | myosin heavy chain kinase A, putative | 0.0139 | 0.7305 | 1 |
Echinococcus multilocularis | eukaryotic elongation factor 2 kinase | 0.0139 | 0.7305 | 0.768 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0239 | 0.0239 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.5536 | 1 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 0.0179 | 0.9512 | 0.9512 |
Trichomonas vaginalis | AGC family protein kinase | 0.0013 | 0.0399 | 0.0663 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0023 | 0.0926 | 0.0974 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0107 | 0.5536 | 1 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.1896 | 0.3383 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.001 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0239 | 0.0239 |
Schistosoma mansoni | atypical protein kinase C | 0.0013 | 0.0399 | 0.0399 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.001 | 0.0239 | 0.0251 |
Echinococcus multilocularis | protein kinase c iota type | 0.0013 | 0.0399 | 0.042 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0013 | 0.0399 | 0.0399 |
Brugia malayi | Protein kinase domain containing protein | 0.0013 | 0.0399 | 0.0399 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.001 | 0.0239 | 0.0239 |
Schistosoma mansoni | elongation factor 2 kinase | 0.004 | 0.1896 | 0.1896 |
Onchocerca volvulus | Serine\/threonine protein kinase homolog | 0.0179 | 0.9512 | 1 |
Echinococcus multilocularis | proto oncogene serine:threonine protein kinase | 0.0179 | 0.9512 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0188 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0239 | 0.0239 |
Brugia malayi | MHCK/EF2 kinase domain family protein | 0.0139 | 0.7305 | 0.7305 |
Echinococcus granulosus | proto oncogene serine:threonine protein kinase | 0.0179 | 0.9512 | 1 |
Echinococcus granulosus | roundabout 2 | 0.0016 | 0.0571 | 0.06 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0013 | 0.0399 | 0.042 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0013 | 0.0399 | 0.042 |
Echinococcus multilocularis | roundabout 2 | 0.0016 | 0.0571 | 0.06 |
Entamoeba histolytica | protein kinase, putative | 0.0038 | 0.1783 | 0.3179 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0024 | 0.1016 | 0.1068 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 0.0179 | 0.9512 | 0.9512 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.2609 | 0.4679 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0107 | 0.5536 | 0.5821 |
Schistosoma mansoni | kinase | 0.0055 | 0.2685 | 0.2685 |
Brugia malayi | Serine/threonine-protein kinase Pim-3 | 0.0179 | 0.9512 | 0.9512 |
Echinococcus granulosus | eukaryotic elongation factor 2 kinase | 0.0139 | 0.7305 | 0.768 |
Entamoeba histolytica | protein kinase 2, putative | 0.0024 | 0.1016 | 0.1783 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.5536 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.5536 | 1 |
Echinococcus multilocularis | Immunoglobulin | 0.001 | 0.0239 | 0.0251 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0024 | 0.1016 | 0.5 |
Schistosoma mansoni | vesicular amine transporter | 0.001 | 0.0239 | 0.0239 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.1896 | 0.3383 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0027 | 0.1142 | 0.2012 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0013 | 0.0399 | 0.0399 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.5536 | 1 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0013 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0036 | 0.1657 | 0.1657 |
Echinococcus granulosus | nervana 2 | 0.0023 | 0.0926 | 0.0974 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0107 | 0.5536 | 0.5821 |
Schistosoma mansoni | serine/threonine kinase | 0.0013 | 0.0399 | 0.0399 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0013 | 0.0399 | 0.042 |
Echinococcus granulosus | Immunoglobulin | 0.001 | 0.0239 | 0.0251 |
Trichomonas vaginalis | AGC family protein kinase | 0.0038 | 0.1783 | 0.3179 |
Toxoplasma gondii | AGC kinase | 0.0036 | 0.1657 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.5536 | 1 |
Echinococcus multilocularis | neuroglian | 0.0013 | 0.0385 | 0.0405 |
Trichomonas vaginalis | AGC family protein kinase | 0.0016 | 0.0525 | 0.0892 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0013 | 0.0399 | 0.042 |
Trichomonas vaginalis | serine/threonine-protein kinase sgk, putative | 0.0012 | 0.031 | 0.05 |
Brugia malayi | Protein kinase domain containing protein | 0.0179 | 0.9512 | 0.9512 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0013 | 0.0399 | 0.042 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0013 | 0.0399 | 0.042 |
Entamoeba histolytica | hypothetical protein, conserved | 0.004 | 0.1896 | 0.3383 |
Schistosoma mansoni | elongation factor 2 kinase | 0.004 | 0.1896 | 0.1896 |
Brugia malayi | Protein kinase domain containing protein | 0.0038 | 0.1783 | 0.1783 |
Entamoeba histolytica | protein kinase, putative | 0.0038 | 0.1783 | 0.3179 |
Brugia malayi | protein kinase C II. | 0.0013 | 0.0399 | 0.0399 |
Echinococcus multilocularis | Immunoglobulin | 0.001 | 0.0239 | 0.0251 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.2609 | 0.4679 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0013 | 0.0399 | 0.0399 |
Trypanosoma cruzi | myosin heavy chain kinase A, putative | 0.0139 | 0.7305 | 1 |
Trypanosoma cruzi | myosin heavy chain kinase A, putative | 0.0139 | 0.7305 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0038 | 0.1783 | 0.3179 |
Entamoeba histolytica | protein kinase, putative | 0.004 | 0.1896 | 0.3383 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0038 | 0.1783 | 0.1783 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0013 | 0.0399 | 0.042 |
Leishmania major | myosin heavy chain kinase a-like protein | 0.0139 | 0.7305 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0107 | 0.5536 | 0.7187 |
Trypanosoma brucei | myosin heavy chain kinase A, putative | 0.0139 | 0.7305 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0107 | 0.5536 | 0.7187 |
Trichomonas vaginalis | AGC family protein kinase | 0.0038 | 0.1783 | 0.3179 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | CAMK/CAMKL/CHK1 protein kinase | 0.0188 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.1896 | 0.3383 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.