Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0403 | 0.1488 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0403 | 0.1488 | 0.016 |
Echinococcus granulosus | acetylcholinesterase | 0.2388 | 1 | 1 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0467 | 0.1759 | 0.0474 |
Brugia malayi | Carboxylesterase family protein | 0.2388 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0403 | 0.1488 | 0.0752 |
Loa Loa (eye worm) | hypothetical protein | 0.0403 | 0.1488 | 0.0867 |
Loa Loa (eye worm) | carboxylesterase | 0.0403 | 0.1488 | 0.0867 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0403 | 0.1488 | 1 |
Onchocerca volvulus | 0.0403 | 0.1488 | 1 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0403 | 0.1488 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0403 | 0.1488 | 0.0867 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0268 | 0.0905 | 0.378 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0403 | 0.1488 | 0.016 |
Schistosoma mansoni | gliotactin | 0.0403 | 0.1488 | 0.016 |
Echinococcus granulosus | carboxylesterase 5A | 0.2388 | 1 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0351 | 0.1264 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0431 | 0.1605 | 0.0993 |
Schistosoma mansoni | acetylcholinesterase | 0.0403 | 0.1488 | 0.016 |
Brugia malayi | Carboxylesterase family protein | 0.0403 | 0.1488 | 0.0752 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0403 | 0.1488 | 0.016 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0403 | 0.1488 | 0.016 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.2388 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2388 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0403 | 0.1488 | 0.0867 |
Loa Loa (eye worm) | carboxylesterase | 0.2388 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0403 | 0.1488 | 1 |
Onchocerca volvulus | 0.0403 | 0.1488 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.2388 | 1 | 1 |
Onchocerca volvulus | 0.0403 | 0.1488 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0403 | 0.1488 | 0.0867 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0403 | 0.1488 | 0.016 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.2388 | 1 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0351 | 0.1264 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0351 | 0.1264 | 1 |
Brugia malayi | hypothetical protein | 0.0403 | 0.1488 | 0.0752 |
Brugia malayi | Carboxylesterase family protein | 0.0403 | 0.1488 | 0.0752 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0403 | 0.1488 | 1 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.1018 | 0.4123 | 0.3615 |
Loa Loa (eye worm) | hypothetical protein | 0.0403 | 0.1488 | 0.0867 |
Loa Loa (eye worm) | carboxylesterase | 0.0403 | 0.1488 | 0.0867 |
Brugia malayi | Carboxylesterase family protein | 0.0403 | 0.1488 | 0.0752 |
Echinococcus multilocularis | carboxylesterase 5A | 0.2388 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0403 | 0.1488 | 0.0867 |
Loa Loa (eye worm) | hypothetical protein | 0.0802 | 0.3198 | 0.2701 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0351 | 0.1264 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0057 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.2388 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0403 | 0.1488 | 0.0867 |
Echinococcus multilocularis | acetylcholinesterase | 0.2388 | 1 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0242 | 0.0796 | 0.0124 |
Echinococcus multilocularis | acetylcholinesterase | 0.2388 | 1 | 1 |
Onchocerca volvulus | 0.0403 | 0.1488 | 1 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0403 | 0.1488 | 1 |
Onchocerca volvulus | 0.0403 | 0.1488 | 1 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0166 | 0.047 | 0.3643 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.