Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0151 | 0.0293 | 0.5 |
Onchocerca volvulus | 0.0151 | 0.0293 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Mycobacterium tuberculosis | Possible transmembrane cation transporter | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Loa Loa (eye worm) | potassium voltage-gated channel subfamily Q member 5 | 0.0151 | 0.0293 | 0.0284 |
Schistosoma mansoni | hypothetical protein | 0.3959 | 1 | 1 |
Echinococcus multilocularis | TWiK family of potassium channels protein 7 | 0.0151 | 0.0293 | 0.0262 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Echinococcus multilocularis | twik family of potassium channels | 0.0151 | 0.0293 | 0.0262 |
Echinococcus multilocularis | serotonin receptor | 0.0127 | 0.0234 | 0.0202 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.155 | 0.3859 | 0.3853 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0234 | 0.0225 |
Toxoplasma gondii | ion channel protein | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Loa Loa (eye worm) | large conductance calcium-activated potassium channel alpha subunit ai | 0.0151 | 0.0293 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Loa Loa (eye worm) | uncoordinated protein 58 | 0.0151 | 0.0293 | 0.0284 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 39A | 0.0151 | 0.0293 | 1 |
Brugia malayi | hypothetical protein | 0.0151 | 0.0293 | 1 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0151 | 0.0293 | 0.0271 |
Trypanosoma cruzi | ion transport protein, putative | 0.0151 | 0.0293 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Echinococcus granulosus | calcium activated potassium channel variant | 0.0151 | 0.0293 | 0.0262 |
Echinococcus granulosus | potassium channel subfamily K | 0.0151 | 0.0293 | 0.0262 |
Echinococcus multilocularis | calcium activated potassium channel variant | 0.0151 | 0.0293 | 0.0262 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog | 0.0151 | 0.0293 | 1 |
Echinococcus multilocularis | potassium channel subfamily K | 0.0151 | 0.0293 | 0.0262 |
Leishmania major | potassium channel subunit-like protein | 0.0151 | 0.0293 | 0.5 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 32 | 0.0151 | 0.0293 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Echinococcus multilocularis | potassium channel subfamily K 8 | 0.0151 | 0.0293 | 0.0262 |
Schistosoma mansoni | calcium-activated potassium channel | 0.294 | 0.7403 | 0.7397 |
Brugia malayi | hypothetical protein | 0.0151 | 0.0293 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Onchocerca volvulus | 0.0151 | 0.0293 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 13 | 0.0151 | 0.0293 | 1 |
Schistosoma mansoni | calcium-activated potassium channel | 0.3959 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Trypanosoma cruzi | calcium-activated potassium channel, putative | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Echinococcus multilocularis | Two pore potassium channel protein sup 9 | 0.0151 | 0.0293 | 0.0262 |
Loa Loa (eye worm) | hypothetical protein | 0.0868 | 0.2122 | 0.2115 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.3959 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.3959 | 1 | 1 |
Echinococcus granulosus | potassium channel subfamily K 8 | 0.0151 | 0.0293 | 0.0262 |
Giardia lamblia | Hypothetical protein | 0.0151 | 0.0293 | 0.5 |
Echinococcus granulosus | potassium channel subfamily K 8 | 0.0151 | 0.0293 | 0.0262 |
Trypanosoma cruzi | calcium-activated potassium channel, putative | 0.0151 | 0.0293 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.033 | 0.0751 | 0.073 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Onchocerca volvulus | 0.0151 | 0.0293 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Leishmania major | hypothetical protein, conserved | 0.0151 | 0.0293 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0151 | 0.0293 | 0.0271 |
Plasmodium vivax | potassium channel, putative | 0.0151 | 0.0293 | 0.5 |
Plasmodium falciparum | potassium channel | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 17 | 0.0151 | 0.0293 | 1 |
Onchocerca volvulus | 0.0151 | 0.0293 | 0.5 | |
Schistosoma mansoni | calcium-activated potassium channel | 0.0151 | 0.0293 | 0.0271 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0127 | 0.0234 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0151 | 0.0293 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Echinococcus granulosus | twik family of potassium channels | 0.0151 | 0.0293 | 0.0262 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0151 | 0.0293 | 0.0271 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 28 | 0.0151 | 0.0293 | 1 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0151 | 0.0293 | 0.0271 |
Toxoplasma gondii | ion channel protein | 0.0151 | 0.0293 | 0.5 |
Echinococcus granulosus | Two pore potassium channel protein sup 9 | 0.0151 | 0.0293 | 0.0262 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 7 | 0.0151 | 0.0293 | 1 |
Mycobacterium ulcerans | transmembrane cation transporter | 0.0151 | 0.0293 | 0.5 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 39B | 0.0151 | 0.0293 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0151 | 0.0293 | 0.0271 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 30. | 0.0151 | 0.0293 | 1 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0151 | 0.0293 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Echinococcus multilocularis | twik family of potassium channels | 0.0151 | 0.0293 | 0.0262 |
Leishmania major | calcium/potassium channel (CAKC), putative | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | TWK-7 protein | 0.0151 | 0.0293 | 0.0284 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0151 | 0.0293 | 0.0271 |
Leishmania major | hypothetical protein, conserved | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | TWK-28 protein | 0.0151 | 0.0293 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0151 | 0.0293 | 0.5 |
Plasmodium vivax | potassium channel, putative | 0.0151 | 0.0293 | 0.5 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog | 0.0151 | 0.0293 | 1 |
Trypanosoma cruzi | ion transport protein, putative | 0.0151 | 0.0293 | 0.5 |
Leishmania major | ion transport protein-like protein | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Echinococcus granulosus | twik family of potassium channels | 0.0151 | 0.0293 | 0.0262 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 12 | 0.0151 | 0.0293 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Trypanosoma brucei | calcium-activated potassium channel, putative | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Onchocerca volvulus | 0.0151 | 0.0293 | 0.5 | |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0127 | 0.0234 | 0.0211 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0151 | 0.0293 | 0.0271 |
Brugia malayi | Twik (KCNK-like) family of potasium channels, alpha subunit 40 | 0.0151 | 0.0293 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0033 | 0.0023 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 45 | 0.0151 | 0.0293 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Plasmodium falciparum | potassium channel | 0.0151 | 0.0293 | 0.5 |
Echinococcus granulosus | TWiK family of potassium channels protein 7 | 0.0151 | 0.0293 | 0.0262 |
Onchocerca volvulus | 0.0151 | 0.0293 | 0.5 | |
Echinococcus multilocularis | serotonin receptor | 0.0127 | 0.0234 | 0.0202 |
Loa Loa (eye worm) | S-phase kinase-associated protein 1A | 0.0151 | 0.0293 | 0.0284 |
Entamoeba histolytica | calcium-gated potassium channel protein, putative | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Trypanosoma cruzi | calcium/potassium channel (CAKC), putative | 0.0151 | 0.0293 | 0.5 |
Trypanosoma cruzi | calcium/potassium channel (CAKC), putative | 0.0151 | 0.0293 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1391 | 0.3454 | 0.3447 |
Onchocerca volvulus | 0.0151 | 0.0293 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0293 | 0.0284 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 5 | 0.0151 | 0.0293 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0234 | 0.0225 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0151 | 0.0293 | 0.0271 |
Mycobacterium ulcerans | ion transport protein | 0.0151 | 0.0293 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0151 | 0.0293 | 0.5 |
Onchocerca volvulus | 0.0151 | 0.0293 | 0.5 | |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 35 | 0.0151 | 0.0293 | 1 |
Echinococcus multilocularis | potassium channel subfamily K 8 | 0.0151 | 0.0293 | 0.0262 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0039 | 0.0009 | 0.0321 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 24 | 0.0151 | 0.0293 | 1 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 21 | 0.0151 | 0.0293 | 1 |
Trypanosoma brucei | calcium/potassium channel (CAKC), putative | 0.0151 | 0.0293 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.