Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | oxidoreductase, 2OG-Fe(II) oxygenase family protein | 0.0089 | 1 | 1 |
Trypanosoma cruzi | 2OG-Fe(II) oxygenase superfamily, putative | 0.0089 | 1 | 1 |
Toxoplasma gondii | oxidoreductase, 2OG-Fe(II) oxygenase family protein | 0.0089 | 1 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0052 | 0 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0052 | 0 | 0.5 |
Trypanosoma brucei | 2OG-Fe(II) oxygenase superfamily, putative | 0.0089 | 1 | 1 |
Toxoplasma gondii | hypoxia- inducible factor prolyl hydroxylase (phd2), putative | 0.0089 | 1 | 1 |
Schistosoma mansoni | prolyl 4-hydroxylase alpha subunit 1 | 0.0089 | 1 | 1 |
Toxoplasma gondii | tetratricopeptide repeat-containing protein | 0.0089 | 1 | 1 |
Giardia lamblia | Kinase, CMGC GSK | 0.0052 | 0 | 0.5 |
Giardia lamblia | Kinase, CMGC GSK | 0.0052 | 0 | 0.5 |
Onchocerca volvulus | 0.0089 | 1 | 1 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0 | 0.5 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.0052 | 0 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0052 | 0 | 0.5 |
Leishmania major | hypothetical protein, unknown function | 0.0089 | 1 | 1 |
Trypanosoma cruzi | 2OG-Fe(II) oxygenase superfamily, putative | 0.0089 | 1 | 1 |
Echinococcus multilocularis | prolyl 4 hydroxylase subunit alpha 1 | 0.0089 | 1 | 1 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.0052 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Loa Loa (eye worm) | prolyl 4-hydroxylase 2 | 0.0089 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0089 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0 | 0.5 |
Echinococcus granulosus | prolyl 4 hydroxylase subunit alpha 1 | 0.0089 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.