Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0606 | 1 | 1 |
Echinococcus granulosus | Ca2 transporting ATPase plasma membrane | 0.0118 | 0.091 | 0.022 |
Echinococcus granulosus | Na:K ATPase alpha subunit | 0.0311 | 0.4509 | 0.4093 |
Schistosoma mansoni | calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) | 0.0118 | 0.091 | 0.022 |
Brugia malayi | Sodium/potassium-transporting ATPase alpha chain, putative | 0.0268 | 0.3707 | 0.822 |
Toxoplasma gondii | plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 | 0.0118 | 0.091 | 1 |
Echinococcus multilocularis | sodium:potassium transporting ATPase subunit | 0.0606 | 1 | 1 |
Mycobacterium leprae | PROBABLE CATION-TRANSPORTER ATPASE I CTPI | 0.0257 | 0.3503 | 0.5 |
Mycobacterium ulcerans | metal cation transporter p-type ATPase a | 0.03 | 0.4305 | 1 |
Echinococcus granulosus | calcium transporting atpase | 0.0118 | 0.091 | 0.022 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0107 | 0.0706 | 0.7755 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0118 | 0.091 | 1 |
Leishmania major | P-type ATPase, putative | 0.0118 | 0.091 | 1 |
Echinococcus multilocularis | calcium transporting atpase | 0.0118 | 0.091 | 0.022 |
Brugia malayi | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type | 0.0118 | 0.091 | 0.2018 |
Plasmodium falciparum | calcium-transporting ATPase | 0.0118 | 0.091 | 0.5 |
Trypanosoma brucei | calcium-translocating P-type ATPase | 0.0118 | 0.091 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0606 | 1 | 1 |
Plasmodium vivax | P-type ATPase4, putative | 0.0118 | 0.091 | 0.5 |
Schistosoma mansoni | sodium / potassium ATPase beta chain | 0.0606 | 1 | 1 |
Schistosoma mansoni | na+/k+ atpase alpha subunit | 0.0311 | 0.4509 | 0.4093 |
Echinococcus multilocularis | nervana 2 | 0.0606 | 1 | 1 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0606 | 1 | 1 |
Schistosoma mansoni | plasma membrane calcium-transporting atpase | 0.0118 | 0.091 | 0.022 |
Schistosoma mansoni | plasma membrane calcium-transporting atpase | 0.0118 | 0.091 | 0.022 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0118 | 0.091 | 1 |
Echinococcus granulosus | calcium transporting ATPase type 2C member | 0.0118 | 0.091 | 0.022 |
Schistosoma mansoni | calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) | 0.0118 | 0.091 | 0.022 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase, putative | 0.0107 | 0.0706 | 0.7455 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0107 | 0.0706 | 0.7455 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 1 | 0.0107 | 0.0706 | 0.7455 |
Entamoeba histolytica | calcium-transporting P-type ATPase, putative | 0.0118 | 0.091 | 1 |
Echinococcus granulosus | nervana 2 | 0.0606 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.2303 | 0.2219 |
Plasmodium vivax | calcium-transporting ATPase, putative | 0.0118 | 0.091 | 0.5 |
Loa Loa (eye worm) | Na,K-ATPase alpha subunit | 0.0311 | 0.4509 | 0.445 |
Echinococcus granulosus | plasma membrane calcium transporting ATPase 2 | 0.0118 | 0.091 | 0.022 |
Schistosoma mansoni | Na+/K+ transporting ATPase subunit alpha | 0.0311 | 0.4509 | 0.4093 |
Toxoplasma gondii | sarco/endoplasmic reticulum Ca2+-ATPase | 0.0118 | 0.091 | 1 |
Onchocerca volvulus | 0.0606 | 1 | 1 | |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0107 | 0.0706 | 0.7755 |
Loa Loa (eye worm) | hypothetical protein | 0.0311 | 0.4509 | 0.445 |
Echinococcus granulosus | nervana 2 | 0.0606 | 1 | 1 |
Trypanosoma cruzi | Calcium ATPase SERCA-like | 0.0107 | 0.0706 | 0.7455 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0107 | 0.0706 | 0.7755 |
Giardia lamblia | Potassium-transporting ATPase alpha chain 1 | 0.0311 | 0.4509 | 1 |
Brugia malayi | Membrane calcium atpase protein 3 | 0.0118 | 0.091 | 0.2018 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0606 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.3213 | 0.3139 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0107 | 0.0706 | 0.7455 |
Echinococcus multilocularis | Na+:K+ ATPase alpha subunit | 0.0311 | 0.4509 | 0.4093 |
Toxoplasma gondii | P-type ATPase4, putative | 0.0118 | 0.091 | 1 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0606 | 1 | 1 |
Trypanosoma cruzi | calcium motive p-type ATPase, putative | 0.0118 | 0.091 | 1 |
Plasmodium falciparum | non-SERCA-type Ca2+ -transporting P-ATPase | 0.0118 | 0.091 | 0.5 |
Trypanosoma brucei | calcium motive p-type ATPase, putative | 0.0118 | 0.091 | 1 |
Echinococcus granulosus | plasma membrane calcium transporting ATPase | 0.0118 | 0.091 | 0.022 |
Echinococcus multilocularis | Ca2+ transporting ATPase plasma membrane | 0.0118 | 0.091 | 0.022 |
Echinococcus multilocularis | nervana 2 | 0.0606 | 1 | 1 |
Echinococcus multilocularis | plasma membrane calcium transporting ATPase | 0.0118 | 0.091 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0706 | 0.0605 |
Echinococcus multilocularis | Tetracycline resistance leader peptide, TetL | 0.0118 | 0.091 | 0.022 |
Trypanosoma cruzi | calcium motive p-type ATPase, putative | 0.0118 | 0.091 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0606 | 1 | 1 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0606 | 1 | 1 |
Echinococcus granulosus | sodium:potassium transporting ATPase subunit | 0.0606 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0606 | 1 | 1 |
Schistosoma mansoni | transmemberane protein | 0.0606 | 1 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0606 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.2593 | 0.2512 |
Echinococcus multilocularis | calcium transporting ATPase type 2C member | 0.0118 | 0.091 | 0.022 |
Brugia malayi | Na,K-ATPase alpha subunit | 0.0311 | 0.4509 | 1 |
Leishmania major | calcium motive p-type ATPase, putative | 0.0118 | 0.091 | 1 |
Schistosoma mansoni | calcium-transporting atpase 2 (atpase 2) | 0.0118 | 0.091 | 0.022 |
Loa Loa (eye worm) | sodium/potassium-transporting ATPase subunit alpha | 0.0268 | 0.3707 | 0.3639 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0606 | 1 | 1 |
Echinococcus granulosus | nervana 2 | 0.0606 | 1 | 1 |
Onchocerca volvulus | 0.0606 | 1 | 1 | |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0606 | 1 | 1 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0606 | 1 | 1 |
Leishmania major | calcium-transporting ATPase, putative | 0.0118 | 0.091 | 1 |
Echinococcus granulosus | nervana 2 | 0.0606 | 1 | 1 |
Brugia malayi | Probable calcium-transporting ATPase KIAA0703 | 0.0075 | 0.0107 | 0.0238 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 2 | 0.0107 | 0.0706 | 0.7455 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.