Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0058 | 0.0774 | 1 | |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0033 | 0.0311 | 0.5141 |
Giardia lamblia | Methionine aminopeptidase | 0.0046 | 0.0547 | 0.5 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0049 | 0.0605 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0347 | 0.0783 |
Mycobacterium ulcerans | methyltransferase | 0.0058 | 0.0774 | 0.0478 |
Loa Loa (eye worm) | O-methyltransferase | 0.0058 | 0.0774 | 1 |
Mycobacterium tuberculosis | Probable methyltransferase | 0.0058 | 0.0774 | 0.0538 |
Onchocerca volvulus | 0.0058 | 0.0774 | 1 | |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0033 | 0.0311 | 0.5141 |
Brugia malayi | O-methyltransferase family protein | 0.0058 | 0.0774 | 1 |
Schistosoma mansoni | o-methyltransferase | 0.0058 | 0.0774 | 1 |
Schistosoma mansoni | o-methyltransferase | 0.0058 | 0.0774 | 1 |
Brugia malayi | O-methyltransferase family protein | 0.0058 | 0.0774 | 1 |
Plasmodium falciparum | methionine aminopeptidase 2 | 0.0046 | 0.0547 | 0.9034 |
Toxoplasma gondii | methionine aminopeptidase | 0.0033 | 0.0311 | 0.5141 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24 | 0.0046 | 0.0547 | 0.9034 |
Toxoplasma gondii | methionine aminopeptidase | 0.0049 | 0.0605 | 1 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0049 | 0.0605 | 1 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0049 | 0.0605 | 1 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0049 | 0.0605 | 1 |
Entamoeba histolytica | methionine aminopeptidase, putative | 0.0046 | 0.0547 | 1 |
Echinococcus granulosus | methionyl aminopeptidase 2 | 0.0046 | 0.0547 | 0.7733 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0046 | 0.0547 | 0.5 |
Echinococcus multilocularis | methionyl aminopeptidase 2 | 0.0046 | 0.0547 | 0.8012 |
Mycobacterium tuberculosis | Probable catechol-O-methyltransferase | 0.05 | 0.8932 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0774 | 1 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0049 | 0.0605 | 1 |
Schistosoma mansoni | methionyl aminopeptidase 2 (M24 family) | 0.0046 | 0.0547 | 0.5084 |
Plasmodium vivax | methionine aminopeptidase 2, putative | 0.0046 | 0.0547 | 0.9034 |
Trypanosoma brucei | metallo-peptidase, Clan MG, Family M24 | 0.0046 | 0.0547 | 0.9034 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0049 | 0.0605 | 1 |
Wolbachia endosymbiont of Brugia malayi | O-methyltransferase | 0.0058 | 0.0774 | 1 |
Leishmania major | methionine aminopeptidase 2, putative | 0.0046 | 0.0547 | 0.9034 |
Toxoplasma gondii | methionine aminopeptidase 2, putative | 0.0046 | 0.0547 | 0.9034 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0049 | 0.0605 | 1 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0033 | 0.0311 | 0.5141 |
Brugia malayi | O-methyltransferase family protein | 0.0058 | 0.0774 | 1 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0049 | 0.0605 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24 | 0.0046 | 0.0547 | 0.9034 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0049 | 0.0605 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0347 | 0.1233 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0049 | 0.0605 | 0.2565 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0046 | 0.0547 | 0.5 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0033 | 0.0311 | 0.5 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0046 | 0.0547 | 0.5 |
Brugia malayi | initiation factor 2-associated protein. | 0.0046 | 0.0547 | 0.4666 |
Trypanosoma brucei | methionine aminopeptidase 2, putative | 0.0046 | 0.0547 | 0.9034 |
Mycobacterium leprae | PROBABLE METHYLTRANSFERASE | 0.0058 | 0.0774 | 1 |
Schistosoma mansoni | o-methyltransferase | 0.0058 | 0.0774 | 1 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0049 | 0.0605 | 1 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0033 | 0.0311 | 0.5 |
Schistosoma mansoni | o-methyltransferase | 0.0058 | 0.0774 | 1 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0046 | 0.0547 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0347 | 0.0783 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.0049 | 0.0605 | 0.6035 |
Brugia malayi | O-methyltransferase | 0.0058 | 0.0774 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.