Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0162 | 0.9681 | 1 | |
Onchocerca volvulus | 0.0162 | 0.9681 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0162 | 0.9681 | 0.9681 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0162 | 0.9681 | 0.9681 |
Brugia malayi | Cathepsin L-like precursor | 0.0162 | 0.9681 | 0.9681 |
Echinococcus granulosus | cathepsin b | 0.0164 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0109 | 0.308 | 0.308 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0164 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0162 | 0.9681 | 0.9681 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0164 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0164 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0164 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0162 | 0.9681 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0162 | 0.9681 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0162 | 0.9681 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0164 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0164 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0162 | 0.9681 | 0.9681 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Leishmania major | cathepsin L-like protease | 0.0162 | 0.9681 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0162 | 0.9681 | 0.9539 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0162 | 0.9681 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0109 | 0.308 | 0.308 |
Echinococcus multilocularis | cathepsin b | 0.0164 | 1 | 1 |
Onchocerca volvulus | 0.0162 | 0.9681 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0109 | 0.308 | 0.3182 |
Loa Loa (eye worm) | ctsf protein | 0.0162 | 0.9681 | 0.9539 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0162 | 0.9681 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0162 | 0.9681 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0162 | 0.9681 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0162 | 0.9681 | 0.9681 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0162 | 0.9681 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0162 | 0.9681 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0162 | 0.9681 | 0.9681 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Leishmania major | cathepsin L-like protease | 0.0162 | 0.9681 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0109 | 0.308 | 0.308 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0162 | 0.9681 | 0.9681 |
Brugia malayi | cathepsin L-like precursor | 0.0109 | 0.308 | 0.308 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0162 | 0.9681 | 0.9681 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0162 | 0.9681 | 0.9681 |
Onchocerca volvulus | Cathepsin F homolog | 0.0162 | 0.9681 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Leishmania major | cathepsin L-like protease | 0.0162 | 0.9681 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0162 | 0.9681 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0162 | 0.9681 | 0.9539 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0109 | 0.308 | 0.3182 |
Onchocerca volvulus | 0.0162 | 0.9681 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0162 | 0.9681 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0162 | 0.9681 | 0.9681 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0162 | 0.9681 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0162 | 0.9681 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0162 | 0.9681 | 0.9681 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0109 | 0.308 | 0.308 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0162 | 0.9681 | 0.9681 |
Leishmania major | cysteine peptidase A (CPA) | 0.0162 | 0.9681 | 0.5 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0162 | 0.9681 | 0.9681 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0162 | 0.9681 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0162 | 0.9681 | 0.9681 |
Brugia malayi | Cathepsin L-like precursor | 0.0162 | 0.9681 | 0.9681 |
Plasmodium vivax | vivapain-2 | 0.0162 | 0.9681 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0162 | 0.9681 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0162 | 0.9681 | 0.9681 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0162 | 0.9681 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Leishmania major | cathepsin L-like protease | 0.0162 | 0.9681 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0162 | 0.9681 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0162 | 0.9681 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0162 | 0.9681 | 0.9681 |
Brugia malayi | Cathepsin L-like precursor | 0.0109 | 0.308 | 0.308 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0162 | 0.9681 | 0.9681 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0162 | 0.9681 | 0.9681 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0162 | 0.9681 | 1 |
Leishmania major | cathepsin L-like protease | 0.0162 | 0.9681 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0162 | 0.9681 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Plasmodium vivax | vivapain-2 | 0.0162 | 0.9681 | 1 |
Onchocerca volvulus | 0.0162 | 0.9681 | 1 | |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0162 | 0.9681 | 0.9681 |
Onchocerca volvulus | 0.0162 | 0.9681 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.9681 | 0.9539 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0162 | 0.9681 | 0.9681 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0109 | 0.308 | 0.308 |
Echinococcus granulosus | cathepsin b | 0.0164 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Leishmania major | cathepsin L-like protease | 0.0162 | 0.9681 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0162 | 0.9681 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0162 | 0.9681 | 0.9681 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0162 | 0.9681 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0109 | 0.308 | 0.3182 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0162 | 0.9681 | 0.9539 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0162 | 0.9681 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0162 | 0.9681 | 0.9539 |
Onchocerca volvulus | 0.0162 | 0.9681 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.