Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | glutathione s transferase mu | 0.0239 | 0.1444 | 0.1444 |
Echinococcus multilocularis | glutathione S transferase | 0.0202 | 0.1137 | 0.0856 |
Echinococcus granulosus | glutathione S transferase Mu 1 | 0.0101 | 0.0307 | 0.0307 |
Echinococcus multilocularis | glutathione S transferase | 0.0176 | 0.0927 | 0.0639 |
Echinococcus multilocularis | glutathione S transferase | 0.0176 | 0.0927 | 0.0639 |
Onchocerca volvulus | 0.0063 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0618 | 0.4543 | 0.4543 |
Trichomonas vaginalis | glutaminyl-tRNA synthetase, putative | 0.0063 | 0 | 0.5 |
Plasmodium falciparum | glutathione S-transferase | 0.0239 | 0.1444 | 0.5 |
Echinococcus granulosus | glutathione S transferase | 0.0239 | 0.1444 | 0.1444 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0652 | 0.4825 | 0.4661 |
Plasmodium vivax | glutathione S-transferase, putative | 0.0101 | 0.0307 | 0.5 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.1284 | 1 | 1 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.1284 | 1 | 1 |
Echinococcus granulosus | prostaglandin H2 D isomerase | 0.0101 | 0.0307 | 0.0307 |
Echinococcus multilocularis | glutathione S transferase | 0.0239 | 0.1444 | 0.1173 |
Loa Loa (eye worm) | hypothetical protein | 0.1284 | 1 | 1 |
Brugia malayi | glutathione transferase | 0.0618 | 0.4543 | 0.4543 |
Echinococcus multilocularis | glutathione S transferase | 0.0239 | 0.1444 | 0.1173 |
Echinococcus granulosus | glutathione S transferase | 0.0176 | 0.0927 | 0.0927 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0652 | 0.4825 | 0.4825 |
Echinococcus granulosus | glutathione S transferase | 0.0176 | 0.0927 | 0.0927 |
Schistosoma mansoni | GST class-mu | 0.0239 | 0.1444 | 1 |
Schistosoma mansoni | glutathione-S-transferase | 0.0239 | 0.1444 | 1 |
Echinococcus multilocularis | glutathione S transferase | 0.0202 | 0.1137 | 0.0856 |
Echinococcus multilocularis | glutathione S-transferase | 0.0239 | 0.1444 | 0.1173 |
Echinococcus multilocularis | glutathione s transferase mu | 0.0239 | 0.1444 | 0.1173 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.