Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.1459 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1459 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1459 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.0065 | 0.0305 | 0.0305 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0065 | 0.0305 | 1 |
Echinococcus granulosus | CDC7 cell division cycle 7 | 0.1459 | 1 | 1 |
Giardia lamblia | Kinase, CDC7 | 0.1459 | 1 | 1 |
Trypanosoma cruzi | serine/threonine protein kinase, putative | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | Mitogen-activated protein kinase 10, putative | 0.0021 | 0 | 0.5 |
Brugia malayi | cyclin-dependent kinase 9 | 0.0065 | 0.0305 | 0.0305 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0065 | 0.0305 | 0.0305 |
Trypanosoma brucei | protein kinase, putative | 0.0021 | 0 | 0.5 |
Trypanosoma brucei | Mitogen-activated protein kinase 10, putative | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDK9 protein kinase | 0.0065 | 0.0305 | 0.0305 |
Plasmodium vivax | serine/threonine protein kinase KIN, putative | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | kinase | 0.0065 | 0.0305 | 0.0305 |
Onchocerca volvulus | 0.1459 | 1 | 0.5 | |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.0065 | 0.0305 | 0.0305 |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.0075 | 0.037 | 0.037 |
Loa Loa (eye worm) | CDC7 protein kinase | 0.1459 | 1 | 1 |
Onchocerca volvulus | 0.1459 | 1 | 0.5 | |
Trypanosoma cruzi | Mitogen-activated protein kinase 10, putative | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0302 | 0.1952 | 0.1952 |
Plasmodium vivax | cyclin dependent kinase 7 (cdk7), putative | 0.0021 | 0 | 0.5 |
Leishmania major | serine/threonine kinase-like protein, putative | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.0075 | 0.037 | 0.037 |
Plasmodium falciparum | MO15-related protein kinase | 0.0021 | 0 | 0.5 |
Leishmania major | mitogen-activated protein kinase, putative,map kinase-like protein | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1459 | 1 | 1 |
Echinococcus multilocularis | CDC7 cell division cycle 7 | 0.1459 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.