Detailed information for compound 835299

Basic information

Technical information
  • TDR Targets ID: 835299
  • Name: 7-[(3-chloro-4-methoxyphenyl)amino]-6-[(4-flu orophenyl)methyl]-7H-pyrrolo[4,3-b]pyridin-5- one
  • MW: 397.83 | Formula: C21H17ClFN3O2
  • H donors: 1 H acceptors: 2 LogP: 3.93 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1Cl)NC1N(Cc2ccc(cc2)F)C(=O)c2c1nccc2
  • InChi: 1S/C21H17ClFN3O2/c1-28-18-9-8-15(11-17(18)22)25-20-19-16(3-2-10-24-19)21(27)26(20)12-13-4-6-14(23)7-5-13/h2-11,20,25H,12H2,1H3
  • InChiKey: WUDKPBQRZSVSQH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 7-[(3-chloro-4-methoxy-phenyl)amino]-6-[(4-fluorophenyl)methyl]-7H-pyrrolo[4,3-b]pyridin-5-one
  • 7-[(3-chloro-4-methoxy-phenyl)amino]-6-(4-fluorobenzyl)-7H-pyrrolo[4,3-b]pyridin-5-one

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0037 0.8595 0.958
Loa Loa (eye worm) hypothetical protein 0.0015 0.2244 0.2501
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Brugia malayi SH2 domain containing protein 0.0037 0.8595 0.958
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Brugia malayi cytokine inducible SH2-containing protein 5 0.0022 0.4138 0.4612
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Schistosoma mansoni tyrosine kinase 0.0037 0.8595 0.8595
Echinococcus granulosus SH2 domain containing protein 7 0.0022 0.4138 0.4612
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0015 0.2244 0.2501
Brugia malayi SH2 domain containing protein 0.0022 0.4138 0.4612
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0015 0.2244 0.2501
Echinococcus granulosus tensin 0.0022 0.4138 0.4612
Schistosoma mansoni protein kinase 0.0015 0.2244 0.2244
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0015 0.2244 0.2725
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Brugia malayi tRNA modification GTPase TrmE family protein 0.0022 0.4138 0.4612
Loa Loa (eye worm) hypothetical protein 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Schistosoma mansoni tensin 0.0022 0.4138 0.4138
Schistosoma mansoni serine/threonine RGC 0.0015 0.2244 0.2244
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0022 0.4138 0.4612
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Brugia malayi hypothetical protein 0.0022 0.4138 0.4612
Brugia malayi Protein kinase domain containing protein 0.0037 0.8595 0.958
Echinococcus granulosus tyrosine kinase 0.0037 0.8595 0.958
Echinococcus granulosus kinase suppressor of Ras 1 0.0015 0.2244 0.2501
Echinococcus granulosus ephrin type A receptor 4 A 0.0015 0.2244 0.2501
Loa Loa (eye worm) TK/FER protein kinase 0.0037 0.8595 0.958
Brugia malayi hypothetical protein 0.0015 0.2244 0.2501
Echinococcus granulosus retinal guanylyl cyclase 2 0.0015 0.2244 0.2501
Brugia malayi Variant SH3 domain containing protein 0.0022 0.4138 0.4612
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.2244 0.5
Echinococcus granulosus tyrosine protein kinase Src42A 0.0037 0.8595 0.958
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0037 0.8595 0.958
Loa Loa (eye worm) TK/DDR protein kinase 0.0015 0.2244 0.2501
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0015 0.2244 0.2501
Loa Loa (eye worm) TK protein kinase 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0022 0.4138 0.2981
Schistosoma mansoni protein kinase 0.0015 0.2244 0.2244
Schistosoma mansoni tensin-related 0.0022 0.4138 0.4138
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.8595 0.958
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0022 0.4138 0.4612
Giardia lamblia Protein 21.1 0.0015 0.2244 0.5
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Schistosoma mansoni vav2 0.0022 0.4138 0.4138
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0015 0.2244 0.5
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0015 0.2244 0.2501
Plasmodium vivax tyrosine kinase-like protein, putative 0.0015 0.2244 0.5
Onchocerca volvulus 0.0022 0.4138 0.2981
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Brugia malayi SH2 domain containing protein 0.0022 0.4138 0.4612
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0015 0.2244 0.2501
Echinococcus multilocularis c src tyrosine kinase 0.0037 0.8595 0.958
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0015 0.2244 0.5
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus granulosus hypothetical protein 0.0022 0.4138 0.4612
Echinococcus multilocularis tyrosine protein kinase Blk 0.0037 0.8595 0.958
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Echinococcus multilocularis epidermal growth factor receptor 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.2244 0.2501
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0022 0.4138 0.4612
Schistosoma mansoni tyrosine kinase 0.0037 0.8595 0.8595
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0015 0.2244 0.2501
Echinococcus multilocularis SHC transforming protein 3 0.0022 0.4138 0.4612
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0015 0.2244 0.2501
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Loa Loa (eye worm) hypothetical protein 0.0015 0.2244 0.2501
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.8595 0.958
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0015 0.2244 0.2501
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0015 0.2244 0.2501
Brugia malayi Tensin 0.0022 0.4138 0.4612
Echinococcus multilocularis tyrosine kinase 0.0037 0.8595 0.958
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Echinococcus granulosus tyrosine protein kinase pr2 0.0015 0.2244 0.2501
Echinococcus granulosus activated cdc42 kinase 1 0.0015 0.2244 0.2501
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Echinococcus multilocularis protein kinase 0.0015 0.2244 0.2501
Onchocerca volvulus 0.0037 0.8595 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.8972 1
Echinococcus granulosus signal transduction protein lnk realted 0.0022 0.4138 0.4612
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.2244 0.2725
Echinococcus granulosus voltage gated potassium channel 0.0011 0.1028 0.1145
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0015 0.2244 0.2501
Echinococcus granulosus tyrosine protein kinase csk 0.0015 0.2244 0.2501
Schistosoma mansoni protein kinase 0.0015 0.2244 0.2244
Brugia malayi Tyrosine-protein kinase PR2 0.0015 0.2244 0.2501
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0037 0.8595 0.958
Schistosoma mansoni protein kinase 0.0015 0.2244 0.2244
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Schistosoma mansoni tyrosine kinase 0.0037 0.8595 0.8595
Schistosoma mansoni tyrosine kinase 0.0037 0.8595 0.8595
Brugia malayi Protein kinase domain containing protein 0.0037 0.8595 0.958
Brugia malayi Sex muscle abnormal protein 5 0.0022 0.4138 0.4612
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Brugia malayi Protein kinase domain containing protein 0.0037 0.8595 0.958
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Plasmodium vivax protein kinase, putative 0.0015 0.2244 0.5
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.1028 0.1145
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0.2244 0.2501
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Brugia malayi Tyrosine-protein kinase abl-1 0.0037 0.8595 0.958
Schistosoma mansoni suppressor of cytokine signaling 0.0022 0.4138 0.4138
Schistosoma mansoni voltage-gated potassium channel 0.0042 1 1
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0022 0.4138 0.4612
Echinococcus granulosus tyrosine protein kinase HCK 0.0015 0.2244 0.2501
Loa Loa (eye worm) SH2 domain-containing protein 0.0022 0.4138 0.4612
Echinococcus granulosus suppressor of cytokine signaling 7 0.0022 0.4138 0.4612
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.2244 0.2725
Echinococcus granulosus expressed conserved protein 0.0022 0.4138 0.4612
Brugia malayi C-terminal src kinase protein 1 0.0015 0.2244 0.2501
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0022 0.4138 0.4612
Echinococcus multilocularis tyrosine protein kinase csk 0.0015 0.2244 0.2501
Loa Loa (eye worm) hypothetical protein 0.0011 0.1028 0.1145
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Echinococcus granulosus N chimaerin 0.0022 0.4138 0.4612
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0022 0.4138 0.4612
Schistosoma mansoni hypothetical protein 0.0015 0.2244 0.2244
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0015 0.2244 0.5
Echinococcus multilocularis tyrosine kinase 0.0015 0.2244 0.2501
Leishmania major protein kinase, putative 0.0015 0.2244 0.5
Loa Loa (eye worm) TK/FER protein kinase 0.0037 0.8595 0.958
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Loa Loa (eye worm) hypothetical protein 0.0037 0.8595 0.958
Schistosoma mansoni shc transforming protein 0.0022 0.4138 0.4138
Plasmodium vivax tyrosine kinase-like protein, putative 0.0015 0.2244 0.5
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0011 0.1028 0.1145
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis STE family protein kinase 0.0015 0.2244 0.2725
Echinococcus multilocularis tyrosine protein kinase csk 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trypanosoma cruzi protein kinase, putative 0.0015 0.2244 0.5
Echinococcus multilocularis protein tyrosine kinase 0.0015 0.2244 0.2501
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0015 0.2244 0.2501
Loa Loa (eye worm) TK/FER protein kinase 0.0037 0.8595 0.958
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0.2244 0.2501
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0015 0.2244 0.2501
Echinococcus granulosus SH2 motif 0.0022 0.4138 0.4612
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Echinococcus granulosus c src tyrosine kinase 0.0037 0.8595 0.958
Brugia malayi SH2 domain containing protein 0.0022 0.4138 0.4612
Echinococcus granulosus activated cdc42 kinase 1 0.0015 0.2244 0.2501
Echinococcus granulosus insulin receptor 0.0015 0.2244 0.2501
Echinococcus multilocularis signal transduction protein lnk realted 0.0022 0.4138 0.4612
Schistosoma mansoni protein tyrosine kinase 0.0015 0.2244 0.2244
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0037 0.8595 0.958
Echinococcus granulosus SH2 domain containing adapter protein F 0.0022 0.4138 0.4612
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0015 0.2244 0.2244
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus granulosus protein tyrosine kinase 0.0015 0.2244 0.2501
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0015 0.2244 0.2244
Schistosoma mansoni hypothetical protein 0.0022 0.4138 0.4138
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) TK/Met protein kinase 0.0015 0.2244 0.2501
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0022 0.4138 0.4138
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.2244 0.2501
Echinococcus granulosus suppressor of cytokine signaling 6 0.0022 0.4138 0.4612
Echinococcus granulosus tyrosine protein kinase Src42A 0.0022 0.4138 0.4612
Loa Loa (eye worm) TK/FER protein kinase 0.0037 0.8595 0.958
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0015 0.2244 0.2501
Echinococcus multilocularis heat shock protein 70 0.0015 0.2244 0.2501
Toxoplasma gondii protein kinase domain-containing protein 0.0015 0.2244 0.5
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis TK family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) TK/INSR protein kinase 0.0015 0.2244 0.2501
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.8236 1
Loa Loa (eye worm) TK/EPH protein kinase 0.0015 0.2244 0.2501
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0015 0.2244 0.2725
Echinococcus granulosus NCK adaptor protein 0.0022 0.4138 0.4612
Leishmania major protein kinase, putative 0.0015 0.2244 0.5
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0015 0.2244 0.2244
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0015 0.2244 0.2501
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.8595 0.958
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Schistosoma mansoni nck2/grb4 0.0022 0.4138 0.4138
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Schistosoma mansoni adapter molecule crk 0.0022 0.4138 0.4138
Brugia malayi Raf kinase 0.0015 0.2244 0.2501
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0022 0.4138 0.4612
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Trypanosoma brucei Pseudokinase, putative 0.0015 0.2244 0.5
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0015 0.2244 0.2501
Loa Loa (eye worm) TK protein kinase 0.0015 0.2244 0.2501
Loa Loa (eye worm) hypothetical protein 0.0015 0.2244 0.2501
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0.2244 0.2501
Loa Loa (eye worm) TK protein kinase 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Echinococcus granulosus tyrosine protein kinase Fyn 0.0037 0.8595 0.958
Echinococcus granulosus raf serine:threonine protein kinase 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0015 0.2244 0.2501
Loa Loa (eye worm) TK protein kinase 0.0015 0.2244 0.2501
Brugia malayi integrin-linked kinase 0.0015 0.2244 0.2501
Echinococcus granulosus epidermal growth factor receptor 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) TK protein kinase 0.0015 0.2244 0.2501
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0037 0.8595 0.958
Loa Loa (eye worm) TK/FER protein kinase 0.0037 0.8595 0.958
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.2244 0.2725
Schistosoma mansoni tyrosine protein kinase 0.0015 0.2244 0.2244
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.2244 0.2725
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus granulosus tyrosine protein kinase Blk 0.0037 0.8595 0.958
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0015 0.2244 0.2501
Brugia malayi Protein kinase domain containing protein 0.0037 0.8595 0.958
Loa Loa (eye worm) TK/FER protein kinase 0.0037 0.8595 0.958
Schistosoma mansoni protein kinase 0.0015 0.2244 0.2244
Echinococcus granulosus epidermal growth factor receptor 0.0015 0.2244 0.2501
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0037 0.8595 0.958
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0015 0.2244 0.2501
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.2244 0.2244
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) hypothetical protein 0.0015 0.2244 0.2501
Echinococcus multilocularis tyrosine protein kinase pr2 0.0015 0.2244 0.2501
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0022 0.4138 0.4612
Echinococcus granulosus retinal guanylyl cyclase 2 0.0015 0.2244 0.2501
Brugia malayi Variant SH3 domain containing protein 0.0022 0.4138 0.4612
Onchocerca volvulus 0.0022 0.4138 0.2981
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.4138 0.4612
Echinococcus granulosus tyrosine protein kinase Fyn 0.0037 0.8595 0.958
Onchocerca volvulus 0.0037 0.8595 1
Brugia malayi hypothetical protein 0.0015 0.2244 0.2501
Echinococcus granulosus activin receptor type 0.0015 0.2244 0.2501
Loa Loa (eye worm) TK/FER protein kinase 0.0037 0.8595 0.958
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Schistosoma mansoni protein kinase 0.0015 0.2244 0.2244
Loa Loa (eye worm) TK protein kinase 0.0015 0.2244 0.2501
Loa Loa (eye worm) SH2 domain-containing protein 0.0022 0.4138 0.4612
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.1028 0.1028
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0037 0.8595 0.958
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Brugia malayi Furin-like cysteine rich region family protein 0.0015 0.2244 0.2501
Toxoplasma gondii protein kinase 0.0015 0.2244 0.5
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.2244 0.5
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Echinococcus granulosus fibroblast growth factor receptor 4 0.0015 0.2244 0.2501
Schistosoma mansoni protein kinase 0.0015 0.2244 0.2244
Loa Loa (eye worm) hypothetical protein 0.0015 0.2244 0.2501
Brugia malayi SH2 domain containing protein 0.0037 0.8595 0.958
Brugia malayi SH2 domain containing protein 0.0022 0.4138 0.4612
Echinococcus granulosus receptor type guanylyl cyclase 0.0015 0.2244 0.2501
Schistosoma mansoni growth factor receptor-bound protein 0.0022 0.4138 0.4138
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Echinococcus multilocularis protein KINase family member (kin 25) 0.0015 0.2244 0.2501
Loa Loa (eye worm) TK protein kinase 0.0015 0.2244 0.2501
Echinococcus granulosus protein kinase 0.0015 0.2244 0.2501
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0022 0.4138 0.4612
Echinococcus multilocularis NCK adaptor protein 0.0022 0.4138 0.4612
Schistosoma mansoni tensin-related 0.0022 0.4138 0.4138
Echinococcus multilocularis tyrosine protein kinase csk 0.0015 0.2244 0.2501
Echinococcus multilocularis tyrosine protein kinase HCK 0.0015 0.2244 0.2501
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.1028 0.1028
Brugia malayi Protein kinase domain containing protein 0.0037 0.8595 0.958
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Brugia malayi SH2 domain containing protein 0.0022 0.4138 0.4612
Schistosoma mansoni growth factor receptor-bound protein 0.0022 0.4138 0.4138
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.2244 0.2501
Echinococcus granulosus tyrosine protein kinase Srms 0.0037 0.8595 0.958
Brugia malayi hypothetical protein 0.0037 0.8595 0.958
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis protein tyrosine kinase, putative 0.0015 0.2244 0.2725
Echinococcus multilocularis epidermal growth factor receptor 0.0015 0.2244 0.2501
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Schistosoma mansoni tensin 0.0022 0.4138 0.4138
Toxoplasma gondii STE kinase 0.0015 0.2244 0.5
Loa Loa (eye worm) TK/ACK protein kinase 0.0015 0.2244 0.2501
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0022 0.4138 0.4612
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.8972 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.4138 0.4612
Echinococcus multilocularis insulin receptor 0.0015 0.2244 0.2501
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0022 0.4138 0.4612
Echinococcus multilocularis tensin 0.0022 0.4138 0.4612
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Loa Loa (eye worm) hypothetical protein 0.0015 0.2244 0.2501
Loa Loa (eye worm) SH2 domain-containing protein 0.0022 0.4138 0.4612
Loa Loa (eye worm) hypothetical protein 0.0015 0.2244 0.2501
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Echinococcus multilocularis kinase suppressor of Ras 1 0.0015 0.2244 0.2501
Schistosoma mansoni protein kinase 0.0015 0.2244 0.2244
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0015 0.2244 0.2725
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.2244 0.2244
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Brugia malayi Variant SH3 domain containing protein 0.0022 0.4138 0.4612
Echinococcus multilocularis SH2 motif 0.0022 0.4138 0.4612
Loa Loa (eye worm) SRC-1 0.0037 0.8595 0.958
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0015 0.2244 0.2501
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0015 0.2244 0.5
Brugia malayi bone morphogenetic protein type 1 receptor 0.0015 0.2244 0.2501
Brugia malayi STAT protein, DNA binding domain containing protein 0.0022 0.4138 0.4612
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Loa Loa (eye worm) TK/ALK protein kinase 0.0015 0.2244 0.2501
Loa Loa (eye worm) STAT protein 0.0022 0.4138 0.4612
Schistosoma mansoni tyrosine kinase 0.0037 0.8595 0.8595
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0015 0.2244 0.2501
Giardia lamblia Kinase, NEK 0.0015 0.2244 0.5
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0037 0.8595 0.958
Onchocerca volvulus 0.0022 0.4138 0.2981
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0037 0.8595 0.958
Onchocerca volvulus 0.0022 0.4138 0.2981
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0022 0.4138 0.2981
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.2244 0.2725
Echinococcus multilocularis activated cdc42 kinase 1 0.0015 0.2244 0.2501
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0015 0.2244 0.2501
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0022 0.4138 0.4612
Loa Loa (eye worm) TK/ABL protein kinase 0.0037 0.8595 0.958
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0015 0.2244 0.2501
Loa Loa (eye worm) TK protein kinase 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus multilocularis ephrin type A receptor 4 A 0.0015 0.2244 0.2501
Loa Loa (eye worm) hypothetical protein 0.0015 0.2244 0.2501
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0037 0.8595 0.958
Brugia malayi ephrin receptor 1 precursor 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus multilocularis raf serine:threonine protein kinase 0.0015 0.2244 0.2501
Echinococcus multilocularis SH2 domain containing protein 7 0.0022 0.4138 0.4612
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0015 0.2244 0.2244
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0015 0.2244 0.2501
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0015 0.2244 0.2501
Plasmodium falciparum protein kinase, putative 0.0015 0.2244 0.5
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0015 0.2244 0.2244
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0015 0.2244 0.2501
Trichomonas vaginalis protein kinase atn1, putative 0.0015 0.2244 0.2725
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0022 0.4138 0.2981
Loa Loa (eye worm) TK/FER protein kinase 0.0037 0.8595 0.958
Brugia malayi Guanylyl cyclase protein 23 0.0015 0.2244 0.2501
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0022 0.4138 0.4612
Loa Loa (eye worm) TK/FER protein kinase 0.0037 0.8595 0.958
Onchocerca volvulus 0.0022 0.4138 0.2981
Echinococcus multilocularis tensin 0.0022 0.4138 0.4612
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus granulosus tyrosine protein kinase csk 0.0015 0.2244 0.2501
Echinococcus granulosus retinal guanylyl cyclase 2 0.0015 0.2244 0.2501
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0015 0.2244 0.2501
Onchocerca volvulus 0.0037 0.8595 1
Brugia malayi protein-tyrosine kinase 0.0037 0.8595 0.958
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis AGC family protein kinase 0.0015 0.2244 0.2725
Plasmodium falciparum tyrosine kinase-like protein 0.0015 0.2244 0.5
Echinococcus granulosus tyrosine protein kinase Lyn 0.0037 0.8595 0.958
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0022 0.4138 0.4138
Loa Loa (eye worm) TK/RYK protein kinase 0.0015 0.2244 0.2501
Echinococcus granulosus growth factor receptor bound protein 2 0.0022 0.4138 0.4612
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0015 0.2244 0.2501
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.8595 0.958
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0015 0.2244 0.2501
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Echinococcus multilocularis N chimaerin 0.0022 0.4138 0.4612
Loa Loa (eye worm) TK/EGFR protein kinase 0.0015 0.2244 0.2501
Echinococcus granulosus tyrosine kinase 0.0015 0.2244 0.2501
Echinococcus multilocularis receptor type guanylyl cyclase 0.0015 0.2244 0.2501
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0022 0.4138 0.4612
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.1028 0.1145
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0015 0.2244 0.2501
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.2244 0.2501
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0015 0.2244 0.2501
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.2244 0.2501
Schistosoma mansoni signal transduction protein lnk-related 0.0022 0.4138 0.4138
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Echinococcus multilocularis 0.0022 0.4138 0.4612
Echinococcus multilocularis tyrosine protein kinase Srms 0.0037 0.8595 0.958
Echinococcus multilocularis protein kinase 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.2244 0.2501
Brugia malayi SH2 domain containing protein 0.0022 0.4138 0.4612
Onchocerca volvulus 0.0022 0.4138 0.2981
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0015 0.2244 0.2501
Onchocerca volvulus 0.0037 0.8595 1
Loa Loa (eye worm) serine/threonine protein kinase 0.0015 0.2244 0.2501
Echinococcus multilocularis growth factor receptor bound protein 2 0.0022 0.4138 0.4612
Loa Loa (eye worm) TK/CSK protein kinase 0.0015 0.2244 0.2501
Echinococcus granulosus tyrosine protein kinase 0.0015 0.2244 0.2501
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.2244 0.5
Echinococcus granulosus tyrosine protein kinase Src64B 0.0037 0.8595 0.958
Brugia malayi Variant SH3 domain containing protein 0.0022 0.4138 0.4612
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0015 0.2244 0.2501
Echinococcus multilocularis tyrosine protein kinase Abl 0.0037 0.8595 0.958
Entamoeba histolytica protein kinase, putative 0.0022 0.4138 0.2981
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Brugia malayi SRC-1 0.0037 0.8595 0.958
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.2244 0.2501
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0022 0.4138 0.4612
Trichomonas vaginalis CAMK family protein kinase 0.0015 0.2244 0.2725
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0022 0.4138 0.4612
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0015 0.2244 0.2244
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Leishmania major hypothetical protein, conserved 0.0015 0.2244 0.5
Loa Loa (eye worm) TK protein kinase 0.0037 0.8595 0.958
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Schistosoma mansoni hypothetical protein 0.0022 0.4138 0.4138
Echinococcus multilocularis tyrosine protein kinase 0.0015 0.2244 0.2501
Echinococcus granulosus SH2 motif 0.0022 0.4138 0.4612
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0022 0.4138 0.4612
Brugia malayi Receptor family ligand binding region containing protein 0.0015 0.2244 0.2501
Echinococcus multilocularis activin receptor type 0.0015 0.2244 0.2501
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Echinococcus multilocularis tyrosine protein kinase csk 0.0015 0.2244 0.2501
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0022 0.4138 0.4138
Echinococcus multilocularis tyrosine protein kinase shark 0.0037 0.8595 0.958
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) hypothetical protein 0.0033 0.7495 0.8354
Onchocerca volvulus 0.0037 0.8595 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0037 0.8595 0.8595
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.2244 0.2501
Giardia lamblia Kinase 0.0015 0.2244 0.5
Loa Loa (eye worm) TK protein kinase 0.0015 0.2244 0.2501
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0037 0.8595 0.958
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0022 0.4138 0.4138
Echinococcus multilocularis integrin linked protein kinase 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0037 0.8595 0.958
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.2244 0.2244
Schistosoma mansoni SH2A 0.0022 0.4138 0.4138
Echinococcus granulosus SHC transforming protein 3 0.0022 0.4138 0.4612
Echinococcus granulosus tyrosine protein kinase Fyn 0.0037 0.8595 0.958
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.2244 0.2244
Echinococcus multilocularis FL cytokine receptor 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Schistosoma mansoni protein kinase 0.0015 0.2244 0.2244
Echinococcus granulosus tyrosine protein kinase shark 0.0037 0.8595 0.958
Plasmodium falciparum protein kinase, putative 0.0015 0.2244 0.5
Echinococcus granulosus natriuretic peptide receptor 1 0.0015 0.2244 0.2501
Schistosoma mansoni GTPase activating protein 0.0022 0.4138 0.4138
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus granulosus tyrosine kinase 0.0037 0.8595 0.958
Plasmodium falciparum tyrosine kinase-like protein 0.0015 0.2244 0.5
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0022 0.4138 0.4612
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Schistosoma mansoni ephrin receptor 0.0015 0.2244 0.2244
Schistosoma mansoni tyrosine kinase 0.0037 0.8595 0.8595
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus multilocularis SH2 motif 0.0022 0.4138 0.4612
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0015 0.2244 0.2501
Schistosoma mansoni tensin 0.0022 0.4138 0.4138
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0037 0.8595 0.958
Loa Loa (eye worm) hypothetical protein 0.0015 0.2244 0.2501
Schistosoma mansoni ephrin receptor 0.0015 0.2244 0.2244
Onchocerca volvulus 0.0037 0.8595 1
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) TK/FER protein kinase 0.0037 0.8595 0.958
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.8972 1
Trypanosoma brucei protein kinase, putative 0.0015 0.2244 0.5
Loa Loa (eye worm) TK/FAK protein kinase 0.0015 0.2244 0.2501
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Loa Loa (eye worm) hypothetical protein 0.0015 0.2244 0.2501
Echinococcus granulosus tyrosine protein kinase csk 0.0015 0.2244 0.2501
Echinococcus granulosus tyrosine protein kinase ABL1 0.0037 0.8595 0.958
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) protein kinase domain-containing protein 0.0015 0.2244 0.2501
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Trypanosoma brucei Flagellum attachment zone protein 20 0.0015 0.2244 0.5
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0015 0.2244 0.2725
Brugia malayi SH2 domain containing protein 0.0022 0.4138 0.4612
Schistosoma mansoni suppressor of cytokine signaling 0.0022 0.4138 0.4138
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0037 0.8595 1
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Plasmodium falciparum protein kinase, putative 0.0015 0.2244 0.5
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Trypanosoma cruzi protein kinase, putative 0.0015 0.2244 0.5
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.1028 0.1145
Giardia lamblia Kinase, NEK 0.0015 0.2244 0.5
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) hypothetical protein 0.0015 0.2244 0.2501
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0022 0.4138 0.4612
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0.2244 0.2501
Brugia malayi Protein kinase domain containing protein 0.0015 0.2244 0.2501
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.2244 0.2725
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Schistosoma mansoni protein kinase 0.0015 0.2244 0.2244
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Loa Loa (eye worm) TK/ROR protein kinase 0.0015 0.2244 0.2501
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.8972 1
Schistosoma mansoni tyrosine kinase 0.0015 0.2244 0.2244
Echinococcus multilocularis transfer RNA-Thr 0.0015 0.2244 0.2501
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.2244 0.2725
Loa Loa (eye worm) hypothetical protein 0.0022 0.4138 0.4612
Brugia malayi RhoGAP domain containing protein 0.0022 0.4138 0.4612
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0022 0.4138 0.4138
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.8236 1
Schistosoma mansoni protein kinase 0.0015 0.2244 0.2244
Entamoeba histolytica SH2 domain containing protein 0.0022 0.4138 0.2981
Echinococcus granulosus integrin linked protein kinase 0.0015 0.2244 0.2501
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0015 0.2244 0.2501
Trichomonas vaginalis TKL family protein kinase 0.0015 0.2244 0.2725
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0037 0.8595 0.958
Echinococcus multilocularis natriuretic peptide receptor 1 0.0015 0.2244 0.2501
Echinococcus multilocularis SH2 motif 0.0022 0.4138 0.4612
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.2244 0.2501

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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