Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | endonuclease G, putative | 0.0128 | 0 | 0.5 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0282 | 0.4673 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.2563 | 0.1195 |
Leishmania major | DNA/RNA non-specific endonuclease-like protein | 0.0128 | 0 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0212 | 0.2563 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0179 | 0.1553 | 0.6061 |
Echinococcus multilocularis | ectonucleotide | 0.0179 | 0.1553 | 0.6061 |
Trypanosoma brucei | endonuclease G, putative | 0.0128 | 0 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4673 | 0.5 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0138 | 0.0311 | 0.5 |
Onchocerca volvulus | 0.0459 | 1 | 1 | |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0179 | 0.1553 | 0.6061 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.2563 | 0.1195 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0212 | 0.2563 | 0.2563 |
Trypanosoma brucei | endonuclease G, putative | 0.0128 | 0 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0212 | 0.2563 | 1 |
Trypanosoma brucei | endonuclease G, putative | 0.0128 | 0 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0212 | 0.2563 | 1 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0212 | 0.2563 | 0.2563 |
Echinococcus granulosus | ectonucleotide | 0.0179 | 0.1553 | 0.6061 |
Schistosoma mansoni | hypothetical protein | 0.0459 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4673 | 0.5 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0459 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4673 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4673 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.2563 | 0.1195 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0138 | 0.0311 | 0.5 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0212 | 0.2563 | 0.2563 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4673 | 0.5 |
Toxoplasma gondii | DNA/RNA non-specific endonuclease | 0.0128 | 0 | 0.5 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0282 | 0.4673 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4673 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4673 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0212 | 0.2563 | 1 |
Trypanosoma cruzi | endonuclease G, putative | 0.0128 | 0 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0212 | 0.2563 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0212 | 0.2563 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0212 | 0.2563 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4673 | 0.5 |
Leishmania major | endonuclease G, putative | 0.0128 | 0 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0212 | 0.2563 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0212 | 0.2563 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0282 | 0.4673 | 0.5 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0212 | 0.2563 | 0.2563 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0128 | 0 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0212 | 0.2563 | 1 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0138 | 0.0311 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0212 | 0.2563 | 1 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0212 | 0.2563 | 0.2563 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0282 | 0.4673 | 0.5 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0128 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.