Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.01 | 0.383 | 0.383 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0117 | 0.562 | 1 |
Leishmania major | cathepsin L-like protease | 0.0117 | 0.562 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0117 | 0.562 | 0.562 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Leishmania major | cathepsin L-like protease | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0117 | 0.562 | 0.562 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0117 | 0.562 | 0.562 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0117 | 0.562 | 1 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.01 | 0.383 | 0.383 |
Loa Loa (eye worm) | fibroinase | 0.0117 | 0.562 | 0.5415 |
Brugia malayi | Cathepsin L-like precursor | 0.008 | 0.1788 | 0.1788 |
Echinococcus multilocularis | cysteine protease | 0.0117 | 0.562 | 0.562 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.01 | 0.383 | 0.383 |
Entamoeba histolytica | cysteine proteinase, putative | 0.008 | 0.1788 | 0.3182 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1788 | 0.1405 |
Onchocerca volvulus | 0.0117 | 0.562 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.008 | 0.1788 | 0.1788 |
Onchocerca volvulus | 0.0117 | 0.562 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0117 | 0.562 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.016 | 1 | 1 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.01 | 0.383 | 0.383 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0117 | 0.562 | 0.5415 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0117 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0117 | 0.562 | 1 |
Onchocerca volvulus | 0.0117 | 0.562 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0067 | 0.0446 | 0.0794 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.01 | 0.383 | 0.383 |
Brugia malayi | Cathepsin L-like precursor | 0.0117 | 0.562 | 0.562 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1788 | 0.1405 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0067 | 0.0446 | 0.0446 |
Loa Loa (eye worm) | cysteine protease | 0.0117 | 0.562 | 0.5415 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0067 | 0.0446 | 0.0794 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.01 | 0.383 | 0.383 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.008 | 0.1788 | 0.1788 |
Leishmania major | cysteine peptidase A (CPA) | 0.0117 | 0.562 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0117 | 0.562 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.016 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0117 | 0.562 | 1 |
Leishmania major | cathepsin L-like protease | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.1788 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.01 | 0.383 | 0.5329 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0117 | 0.562 | 0.562 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.01 | 0.383 | 0.6815 |
Mycobacterium tuberculosis | Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) | 0.01 | 0.383 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0117 | 0.562 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0117 | 0.562 | 0.562 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0117 | 0.562 | 0.562 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0117 | 0.562 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0117 | 0.562 | 1 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.01 | 0.383 | 0.6541 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.01 | 0.383 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0117 | 0.562 | 1 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.01 | 0.383 | 0.6541 |
Brugia malayi | Cathepsin L-like precursor | 0.0117 | 0.562 | 0.562 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0117 | 0.562 | 0.562 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.008 | 0.1788 | 0.1788 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0067 | 0.0446 | 0.0446 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0117 | 0.562 | 0.562 |
Echinococcus granulosus | cathepsin b | 0.016 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Plasmodium vivax | RNA helicase-1, putative | 0.01 | 0.383 | 0.6815 |
Echinococcus multilocularis | cathepsin b | 0.016 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.008 | 0.1788 | 0.1788 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0117 | 0.562 | 1 |
Onchocerca volvulus | 0.0117 | 0.562 | 1 | |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.01 | 0.383 | 0.6815 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Brugia malayi | eukaryotic initiation factor 4A | 0.01 | 0.383 | 0.383 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.01 | 0.383 | 0.6541 |
Toxoplasma gondii | cathepsin CPL | 0.0117 | 0.562 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0117 | 0.562 | 0.562 |
Onchocerca volvulus | 0.0117 | 0.562 | 1 | |
Plasmodium vivax | vivapain-2 | 0.0117 | 0.562 | 1 |
Onchocerca volvulus | 0.0117 | 0.562 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.01 | 0.383 | 0.6815 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0117 | 0.562 | 0.562 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.01 | 0.383 | 0.383 |
Loa Loa (eye worm) | ctsf protein | 0.0117 | 0.562 | 0.5415 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.01 | 0.383 | 0.6815 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.016 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0117 | 0.562 | 0.562 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0117 | 0.562 | 0.562 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Leishmania major | cathepsin L-like protease | 0.0117 | 0.562 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.016 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0117 | 0.562 | 0.562 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0117 | 0.562 | 0.562 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.01 | 0.383 | 0.6815 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0117 | 0.562 | 0.562 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1788 | 0.1405 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0117 | 0.562 | 0.562 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0117 | 0.562 | 0.562 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.1788 | 0.3182 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0117 | 0.562 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.016 | 1 | 1 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.01 | 0.383 | 0.383 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Treponema pallidum | ATP-dependent RNA helicase | 0.01 | 0.383 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.383 | 0.3542 |
Leishmania major | cathepsin L-like protease | 0.0117 | 0.562 | 1 |
Leishmania major | cathepsin L-like protease | 0.0117 | 0.562 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0117 | 0.562 | 0.562 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0117 | 0.562 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.008 | 0.1788 | 0.1788 |
Onchocerca volvulus | 0.0117 | 0.562 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.562 | 0.5415 |
Onchocerca volvulus | Cathepsin L homolog | 0.0117 | 0.562 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.008 | 0.1788 | 0.1788 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.01 | 0.383 | 0.6815 |
Plasmodium vivax | vivapain-2 | 0.0117 | 0.562 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0117 | 0.562 | 0.562 |
Echinococcus granulosus | cathepsin b | 0.016 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0117 | 0.562 | 0.5415 |
Echinococcus multilocularis | cysteine protease | 0.0117 | 0.562 | 0.562 |
Echinococcus multilocularis | cathepsin b | 0.016 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0117 | 0.562 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0117 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0117 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0117 | 0.562 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.