Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0045 | 0.024 | 0.0255 |
Echinococcus granulosus | acetylcholinesterase | 0.0264 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.024 | 0.024 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.024 | 0.024 |
Echinococcus granulosus | sterol O acyltransferase 1 | 0.023 | 0.849 | 0.849 |
Brugia malayi | hypothetical protein | 0.0045 | 0.024 | 0.024 |
Mycobacterium leprae | conserved hypothetical protein | 0.0039 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.024 | 0.024 |
Echinococcus granulosus | geminin | 0.0184 | 0.6467 | 0.6467 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0045 | 0.024 | 0.024 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0264 | 1 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0045 | 0.024 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.849 | 0.849 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0045 | 0.024 | 0.024 |
Toxoplasma gondii | ABC1 family protein | 0.0039 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.024 | 0.024 |
Echinococcus granulosus | acetylcholinesterase | 0.0264 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0045 | 0.024 | 0.024 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.6467 | 0.6467 |
Echinococcus multilocularis | geminin | 0.0184 | 0.6467 | 0.6467 |
Echinococcus granulosus | neuroligin | 0.0045 | 0.024 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.024 | 0.024 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0045 | 0.024 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0 | 0.5 |
Schistosoma mansoni | sterol O-acyltransferase 1 | 0.023 | 0.849 | 0.849 |
Plasmodium vivax | hypothetical protein, conserved | 0.0039 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0045 | 0.024 | 0.0255 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.6467 | 0.6467 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.024 | 0.024 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0045 | 0.024 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0045 | 0.024 | 0.024 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0264 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0045 | 0.024 | 0.024 |
Echinococcus multilocularis | acetylcholinesterase | 0.0264 | 1 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0045 | 0.024 | 0.024 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0045 | 0.024 | 0.024 |
Schistosoma mansoni | gliotactin | 0.0045 | 0.024 | 0.024 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0039 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.024 | 0.024 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.025 | 0.9403 | 1 |
Onchocerca volvulus | 0.0045 | 0.024 | 1 | |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0045 | 0.024 | 0.024 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.024 | 0.024 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0045 | 0.024 | 0.0255 |
Schistosoma mansoni | acetylcholinesterase | 0.0045 | 0.024 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.024 | 0.024 |
Echinococcus granulosus | carboxylesterase 5A | 0.0264 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0264 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0264 | 1 | 1 |
Onchocerca volvulus | 0.0045 | 0.024 | 1 | |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0045 | 0.024 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0264 | 1 | 1 |
Onchocerca volvulus | 0.0045 | 0.024 | 1 | |
Mycobacterium leprae | Probable lipase LipE | 0.0039 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.024 | 0.024 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0045 | 0.024 | 0.024 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0045 | 0.024 | 0.024 |
Echinococcus multilocularis | sterol O acyltransferase 1 | 0.023 | 0.849 | 0.849 |
Loa Loa (eye worm) | carboxylesterase | 0.0264 | 1 | 1 |
Onchocerca volvulus | 0.0045 | 0.024 | 1 | |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0045 | 0.024 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.7491 | 0.7491 |
Onchocerca volvulus | 0.0045 | 0.024 | 1 | |
Leishmania major | hypothetical protein, conserved | 0.0039 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.024 | 0.024 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0045 | 0.024 | 0.024 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0045 | 0.024 | 0.024 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.