Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Trypanosoma brucei | calcium-activated potassium channel, putative | 0.0116 | 0.0257 | 1 |
Echinococcus granulosus | potassium channel subfamily K 8 | 0.0116 | 0.0257 | 0.0239 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 21 | 0.0116 | 0.0257 | 0.3315 |
Brugia malayi | follicle stimulating hormone receptor | 0.028 | 0.0737 | 1 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 39B | 0.0116 | 0.0257 | 0.3315 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Onchocerca volvulus | 0.0116 | 0.0257 | 0.5 | |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 12 | 0.0116 | 0.0257 | 0.3315 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0372 | 0.1007 | 0.099 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Onchocerca volvulus | 0.0116 | 0.0257 | 0.5 | |
Plasmodium falciparum | potassium channel | 0.0116 | 0.0257 | 1 |
Echinococcus granulosus | potassium channel subfamily K 8 | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Echinococcus multilocularis | potassium channel subfamily K 8 | 0.0116 | 0.0257 | 0.0239 |
Toxoplasma gondii | ion channel protein | 0.0116 | 0.0257 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0116 | 0.0257 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0079 | 0.006 |
Onchocerca volvulus | 0.0116 | 0.0257 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0372 | 0.1007 | 0.099 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0116 | 0.0257 | 0.0239 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 28 | 0.0116 | 0.0257 | 0.3315 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 45 | 0.0116 | 0.0257 | 0.3315 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 39A | 0.0116 | 0.0257 | 0.3315 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0116 | 0.0257 | 1 |
Plasmodium falciparum | potassium channel | 0.0116 | 0.0257 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0079 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Echinococcus granulosus | potassium channel subfamily K | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0053 | 0.0074 | 0.0055 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0116 | 0.0257 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Trypanosoma brucei | calcium/potassium channel (CAKC), putative | 0.0116 | 0.0257 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.0372 | 0.1007 | 0.099 |
Echinococcus granulosus | TWiK family of potassium channels protein 7 | 0.0116 | 0.0257 | 0.0239 |
Brugia malayi | Twik (KCNK-like) family of potasium channels, alpha subunit 40 | 0.0116 | 0.0257 | 0.3315 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Brugia malayi | Thioredoxin reductase | 0.0053 | 0.0074 | 0.0763 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 5 | 0.0116 | 0.0257 | 0.3315 |
Loa Loa (eye worm) | hypothetical protein | 0.1128 | 0.3226 | 0.3213 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0136 | 0.0315 | 1 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog | 0.0116 | 0.0257 | 0.3315 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0116 | 0.0257 | 0.0239 |
Plasmodium vivax | potassium channel, putative | 0.0116 | 0.0257 | 1 |
Trypanosoma cruzi | calcium-activated potassium channel, putative | 0.0116 | 0.0257 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Brugia malayi | RNA, U transporter 1 | 0.0099 | 0.0208 | 0.2622 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Mycobacterium ulcerans | ion transport protein | 0.0116 | 0.0257 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0116 | 0.0257 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Echinococcus granulosus | twik family of potassium channels | 0.0116 | 0.0257 | 0.0239 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 35 | 0.0116 | 0.0257 | 0.3315 |
Plasmodium falciparum | thioredoxin reductase | 0.0053 | 0.0074 | 0.23 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 24 | 0.0116 | 0.0257 | 0.3315 |
Brugia malayi | hypothetical protein | 0.0116 | 0.0257 | 0.3315 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0053 | 0.0074 | 0.0055 |
Schistosoma mansoni | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0116 | 0.0257 | 0.0239 |
Mycobacterium ulcerans | transmembrane cation transporter | 0.0116 | 0.0257 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Trypanosoma cruzi | ion transport protein, putative | 0.0116 | 0.0257 | 1 |
Brugia malayi | hypothetical protein | 0.0116 | 0.0257 | 0.3315 |
Echinococcus multilocularis | TWiK family of potassium channels protein 7 | 0.0116 | 0.0257 | 0.0239 |
Toxoplasma gondii | ion channel protein | 0.0116 | 0.0257 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Leishmania major | trypanothione reductase | 0.0053 | 0.0074 | 0.2878 |
Leishmania major | ion transport protein-like protein | 0.0116 | 0.0257 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.028 | 0.0737 | 0.0719 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | glutathione reductase | 0.0053 | 0.0074 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Trypanosoma cruzi | ion transport protein, putative | 0.0116 | 0.0257 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0116 | 0.0257 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0079 | 0.006 |
Onchocerca volvulus | 0.0116 | 0.0257 | 0.5 | |
Loa Loa (eye worm) | potassium voltage-gated channel subfamily Q member 5 | 0.0116 | 0.0257 | 0.0239 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0116 | 0.0257 | 0.0239 |
Trypanosoma cruzi | calcium/potassium channel (CAKC), putative | 0.0116 | 0.0257 | 1 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 13 | 0.0116 | 0.0257 | 0.3315 |
Loa Loa (eye worm) | S-phase kinase-associated protein 1A | 0.0116 | 0.0257 | 0.0239 |
Leishmania major | hypothetical protein, conserved | 0.0116 | 0.0257 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | TWK-28 protein | 0.0116 | 0.0257 | 0.0239 |
Leishmania major | calcium/potassium channel (CAKC), putative | 0.0116 | 0.0257 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 17 | 0.0116 | 0.0257 | 0.3315 |
Onchocerca volvulus | 0.0116 | 0.0257 | 0.5 | |
Plasmodium vivax | glutathione reductase, putative | 0.0053 | 0.0074 | 0.23 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0136 | 0.0315 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0079 | 0.006 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0116 | 0.0257 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0122 | 0.0275 | 0.8342 |
Onchocerca volvulus | 0.0116 | 0.0257 | 0.5 | |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0055 | 0.0079 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.3438 | 1 | 1 |
Echinococcus multilocularis | twik family of potassium channels | 0.0116 | 0.0257 | 0.0239 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0122 | 0.0275 | 0.8342 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0122 | 0.0275 | 0.8342 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0116 | 0.0257 | 1 |
Echinococcus granulosus | calcium activated potassium channel variant | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Onchocerca volvulus | 0.0116 | 0.0257 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.1193 | 0.3415 | 0.3402 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0116 | 0.0257 | 0.0239 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0116 | 0.0257 | 0.0239 |
Echinococcus granulosus | twik family of potassium channels | 0.0116 | 0.0257 | 0.0239 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0079 | 0.006 |
Onchocerca volvulus | 0.0116 | 0.0257 | 0.5 | |
Trypanosoma cruzi | calcium-activated potassium channel, putative | 0.0116 | 0.0257 | 1 |
Echinococcus multilocularis | twik family of potassium channels | 0.0116 | 0.0257 | 0.0239 |
Mycobacterium tuberculosis | Possible transmembrane cation transporter | 0.0116 | 0.0257 | 0.7609 |
Echinococcus multilocularis | Two pore potassium channel protein sup 9 | 0.0116 | 0.0257 | 0.0239 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0122 | 0.0275 | 0.8342 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0053 | 0.0074 | 0.0055 |
Trypanosoma brucei | trypanothione reductase | 0.0053 | 0.0074 | 0.23 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 32 | 0.0116 | 0.0257 | 0.3315 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0053 | 0.0074 | 0.2878 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0116 | 0.0257 | 1 |
Plasmodium vivax | potassium channel, putative | 0.0116 | 0.0257 | 1 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 30. | 0.0116 | 0.0257 | 0.3315 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0079 | 0.006 |
Mycobacterium tuberculosis | Probable reductase | 0.0122 | 0.0275 | 0.8342 |
Loa Loa (eye worm) | large conductance calcium-activated potassium channel alpha subunit ai | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | TWK-7 protein | 0.0116 | 0.0257 | 0.0239 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0116 | 0.0257 | 0.0239 |
Echinococcus granulosus | snurportin 1 | 0.0372 | 0.1007 | 0.099 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0116 | 0.0257 | 0.0239 |
Brugia malayi | glutathione reductase | 0.0053 | 0.0074 | 0.0763 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0136 | 0.0315 | 1 |
Loa Loa (eye worm) | uncoordinated protein 58 | 0.0116 | 0.0257 | 0.0239 |
Entamoeba histolytica | calcium-gated potassium channel protein, putative | 0.0116 | 0.0257 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Schistosoma mansoni | calcium-activated potassium channel | 0.2194 | 0.6351 | 0.6344 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog | 0.0116 | 0.0257 | 0.3315 |
Echinococcus multilocularis | calcium activated potassium channel variant | 0.0116 | 0.0257 | 0.0239 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0053 | 0.0074 | 0.23 |
Giardia lamblia | Hypothetical protein | 0.0116 | 0.0257 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0055 | 0.0079 | 0.0834 |
Echinococcus multilocularis | potassium channel subfamily K | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.3438 | 1 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0122 | 0.0275 | 0.8342 |
Echinococcus granulosus | Two pore potassium channel protein sup 9 | 0.0116 | 0.0257 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Plasmodium falciparum | glutathione reductase | 0.0053 | 0.0074 | 0.23 |
Echinococcus multilocularis | potassium channel subfamily K 8 | 0.0116 | 0.0257 | 0.0239 |
Schistosoma mansoni | hypothetical protein | 0.3438 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1001 | 0.2853 | 0.2839 |
Schistosoma mansoni | calcium-activated potassium channel | 0.3438 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0079 | 0.006 |
Leishmania major | potassium channel subunit-like protein | 0.0116 | 0.0257 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0917 | 0.2607 | 0.2593 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 7 | 0.0116 | 0.0257 | 0.3315 |
Trypanosoma cruzi | calcium/potassium channel (CAKC), putative | 0.0116 | 0.0257 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0257 | 0.0239 |
Toxoplasma gondii | thioredoxin reductase | 0.0053 | 0.0074 | 0.23 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0136 | 0.0315 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.