Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0617 | 0.4991 | 0.4987 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0009 | 0.0016 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0009 | 0.016 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.0062 | 0.0925 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0062 | 0.1313 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0098 | 0.0586 | 1 |
Giardia lamblia | PHD finger protein 15 | 0.003 | 0.0009 | 0.5 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.1207 | 1 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0009 | 0.0011 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0036 | 0.0062 | 0.106 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0062 | 0.1313 |
Echinococcus granulosus | peregrin | 0.003 | 0.0009 | 0.0149 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.0062 | 0.0053 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0009 | 0.0016 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.1207 | 1 | 1 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.0009 | 0.0149 |
Onchocerca volvulus | 0.0451 | 0.3582 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.1207 | 1 | 1 |
Leishmania major | C-8 sterol isomerase-like protein | 0.1207 | 1 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0238 | 0.1772 | 0.5 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0209 | 0.1528 | 0.152 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.0279 | 0.027 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0098 | 0.0586 | 1 |
Onchocerca volvulus | 0.003 | 0.0009 | 0.0002 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.019 | 0.0181 |
Onchocerca volvulus | 0.0238 | 0.1772 | 0.4936 | |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0009 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0009 | 0.0016 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.0108 | 0.1721 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0009 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0078 | 0.0415 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0098 | 0.0586 | 0.0577 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0009 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0009 | 0.0001 |
Plasmodium falciparum | phd finger protein, putative | 0.003 | 0.0009 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.0062 | 0.0053 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0009 | 0.0001 |
Brugia malayi | Pre-SET motif family protein | 0.0209 | 0.1528 | 0.152 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0009 | 0.0011 |
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.0108 | 0.1844 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.