Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0064 | 0.005 | 0.0208 |
Echinococcus multilocularis | Solute carrier organic anion transporter family | 0.0127 | 0.0546 | 0.0996 |
Onchocerca volvulus | 0.0127 | 0.0546 | 0.0546 | |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0127 | 0.0546 | 0.0546 |
Brugia malayi | hypothetical protein | 0.0448 | 0.3083 | 0.3083 |
Brugia malayi | hypothetical protein | 0.0127 | 0.0546 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0546 | 0.0546 |
Onchocerca volvulus | 0.0064 | 0.005 | 0.005 | |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.005 | 0.005 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0124 | 0.0524 | 0.2175 |
Echinococcus multilocularis | serotonin transporter | 0.0064 | 0.005 | 0.0092 |
Onchocerca volvulus | 0.0127 | 0.0546 | 0.0546 | |
Echinococcus granulosus | geminin | 0.0175 | 0.0926 | 0.1688 |
Onchocerca volvulus | 0.0127 | 0.0546 | 0.0546 | |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0124 | 0.0524 | 0.5 |
Brugia malayi | hypothetical protein | 0.0127 | 0.0546 | 0.0546 |
Schistosoma mansoni | organic anion transporter | 0.0127 | 0.0546 | 0.2266 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0546 | 0.0546 |
Echinococcus granulosus | serotonin transporter | 0.0064 | 0.005 | 0.0092 |
Loa Loa (eye worm) | sodium-independent organic anion transporter | 0.0127 | 0.0546 | 0.0546 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.0926 | 0.3841 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0127 | 0.0546 | 0.0546 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0124 | 0.0524 | 0.0956 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0124 | 0.0524 | 0.0956 |
Echinococcus granulosus | organic anion transporting polypeptide 30B | 0.0127 | 0.0546 | 0.0996 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0064 | 0.005 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0546 | 0.0546 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0124 | 0.0524 | 0.9596 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.0926 | 0.3841 |
Onchocerca volvulus | 0.0127 | 0.0546 | 0.0546 | |
Onchocerca volvulus | Putative organic anion transporter | 0.0127 | 0.0546 | 0.0546 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0124 | 0.0524 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0448 | 0.3083 | 0.3083 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0546 | 0.0546 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0124 | 0.0524 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0124 | 0.0524 | 0.5 |
Trypanosoma cruzi | MFS transporter, putative | 0.0127 | 0.0546 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0546 | 0.0546 |
Onchocerca volvulus | Putative organic anion transporter | 0.0127 | 0.0546 | 0.0546 |
Echinococcus multilocularis | expressed protein | 0.0751 | 0.5485 | 1 |
Echinococcus granulosus | Solute carrier organic anion transporter family | 0.0127 | 0.0546 | 0.0996 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0064 | 0.005 | 0.005 |
Toxoplasma gondii | transporter, major facilitator family protein | 0.0127 | 0.0546 | 1 |
Onchocerca volvulus | 0.0127 | 0.0546 | 0.0546 | |
Schistosoma mansoni | organic anion transporter | 0.0127 | 0.0546 | 0.2266 |
Loa Loa (eye worm) | hypothetical protein | 0.1322 | 1 | 1 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0064 | 0.005 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.005 | 0.005 |
Loa Loa (eye worm) | serotonin transporter b | 0.0064 | 0.005 | 0.005 |
Echinococcus granulosus | expressed protein | 0.0751 | 0.5485 | 1 |
Onchocerca volvulus | 0.0448 | 0.3083 | 0.3083 | |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0064 | 0.005 | 0.0208 |
Loa Loa (eye worm) | hypothetical protein | 0.0448 | 0.3083 | 0.3083 |
Onchocerca volvulus | Putative organic anion transporter | 0.1322 | 1 | 1 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0064 | 0.005 | 0.5 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0127 | 0.0546 | 0.0546 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0124 | 0.0524 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0546 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.005 | 0.005 |
Echinococcus multilocularis | geminin | 0.0175 | 0.0926 | 0.1688 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0124 | 0.0524 | 0.2175 |
Echinococcus multilocularis | organic anion transporting polypeptide 30B | 0.0127 | 0.0546 | 0.0996 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0362 | 0.2411 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.