Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0784 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0784 | 1 | 1 |
Onchocerca volvulus | 0.0784 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0784 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0762 | 0.9398 | 0.9398 |
Onchocerca volvulus | 0.0784 | 1 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0784 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0784 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0762 | 0.9398 | 0.9398 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0784 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0762 | 0.9398 | 0.9398 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0784 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0784 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0784 | 1 | 1 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0762 | 0.9398 | 0.9398 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0784 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0531 | 0.3182 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0784 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0784 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0784 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0531 | 0.3182 | 0.3182 |
Echinococcus multilocularis | cysteine protease | 0.0784 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0531 | 0.3182 | 0.3182 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0784 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0784 | 1 | 1 |
Onchocerca volvulus | 0.0784 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0784 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0784 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0762 | 0.9398 | 0.9398 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0784 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0784 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0531 | 0.3182 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0784 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0784 | 1 | 1 |
Onchocerca volvulus | 0.0784 | 1 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0784 | 1 | 1 |
Onchocerca volvulus | 0.0784 | 1 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0784 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0784 | 1 | 1 |
Onchocerca volvulus | 0.0784 | 1 | 1 | |
Echinococcus multilocularis | cathepsin b | 0.0762 | 0.9398 | 0.9398 |
Leishmania major | cathepsin L-like protease | 0.0784 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0784 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0784 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0762 | 0.9398 | 0.9398 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0784 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0531 | 0.3182 | 0.3182 |
Leishmania major | cysteine peptidase A (CPA) | 0.0784 | 1 | 0.5 |
Loa Loa (eye worm) | fibroinase | 0.0784 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0784 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0784 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0784 | 1 | 0.5 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0784 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0784 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0784 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0762 | 0.9398 | 0.9398 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0531 | 0.3182 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0762 | 0.9398 | 0.9117 |
Onchocerca volvulus | Cathepsin F homolog | 0.0784 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0784 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0762 | 0.9398 | 0.9398 |
Loa Loa (eye worm) | cysteine protease | 0.0784 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0784 | 1 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0784 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0784 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0784 | 1 | 0.5 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0531 | 0.3182 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0784 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0784 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0784 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0531 | 0.3182 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0784 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0784 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0784 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0784 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0784 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0762 | 0.9398 | 0.9398 |
Toxoplasma gondii | cathepsin CPL | 0.0784 | 1 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0784 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0784 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0784 | 1 | 0.5 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0531 | 0.3182 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0784 | 1 | 1 |
Onchocerca volvulus | 0.0784 | 1 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0784 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0531 | 0.3182 | 0.3182 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0784 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0784 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.