Detailed information for compound 847193

Basic information

Technical information
  • TDR Targets ID: 847193
  • Name: 1-(4-bromophenyl)-N-(2,3-dimethylphenyl)-5-me thyltriazole-4-carboxamide
  • MW: 385.258 | Formula: C18H17BrN4O
  • H donors: 1 H acceptors: 3 LogP: 4.34 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Brc1ccc(cc1)n1nnc(c1C)C(=O)Nc1cccc(c1C)C
  • InChi: 1S/C18H17BrN4O/c1-11-5-4-6-16(12(11)2)20-18(24)17-13(3)23(22-21-17)15-9-7-14(19)8-10-15/h4-10H,1-3H3,(H,20,24)
  • InChiKey: RQZVSCAHOHIFPR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(4-bromophenyl)-N-(2,3-dimethylphenyl)-5-methyl-triazole-4-carboxamide
  • 1-(4-bromophenyl)-N-(2,3-dimethylphenyl)-5-methyl-4-triazolecarboxamide
  • 1-(4-bromophenyl)-N-(2,3-dimethylphenyl)-5-methyl-1,2,3-triazole-4-carboxamide
  • ZINC02713313

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus allatostatin A receptor 0.0092 0.1 0.1346
Toxoplasma gondii histone lysine methyltransferase SET8 0.0548 0.743 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0092 0.1 0.1139
Brugia malayi ORL1-like opioid receptor 0.0092 0.1 0.1139
Brugia malayi Pre-SET motif family protein 0.0108 0.122 0.1389
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0092 0.1 0.1346
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0108 0.122 0.1641
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.1 0.1346
Brugia malayi hypothetical protein 0.0092 0.1 0.1139
Brugia malayi Tachykinin-like peptides receptor 99D 0.0092 0.1 0.1139
Schistosoma mansoni biogenic amine receptor 0.0092 0.1 0.1346
Brugia malayi Melatonin receptor type 1A 0.0092 0.1 0.1139
Loa Loa (eye worm) neuropeptide F receptor 0.0092 0.1 0.1139
Brugia malayi Dopamine receptor protein 2 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Schistosoma mansoni neuropeptide receptor 0.0092 0.1 0.1346
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0092 0.1 0.1346
Echinococcus multilocularis sex peptide receptor 0.0092 0.1 0.1346
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0092 0.1 0.1346
Onchocerca volvulus 0.0092 0.1 0.1
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0366 0.0492
Schistosoma mansoni biogenic amine (5HT) receptor 0.0092 0.1 0.1346
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0092 0.1 0.1139
Schistosoma mansoni adenoreceptor 0.0092 0.1 0.1346
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0048 0.0366 0.0492
Brugia malayi G protein-coupled receptor 0.0092 0.1 0.1139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.1 0.1346
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0071 0.0071
Onchocerca volvulus 0.0092 0.1 0.1
Echinococcus multilocularis g protein coupled receptor 0.0092 0.1 0.1346
Brugia malayi Serotonin receptor 0.0092 0.1 0.1139
Echinococcus granulosus neuropeptides capa receptor 0.0092 0.1 0.1346
Echinococcus granulosus neuropeptide Y receptor 0.0092 0.1 0.1346
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0092 0.1 0.1346
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.1 0.1346
Onchocerca volvulus Neuropeptide F receptor homolog 0.0092 0.1 0.1
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.1 0.1346
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0092 0.1 0.1139
Brugia malayi isocitrate dehydrogenase 0.0048 0.0366 0.0417
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0048 0.0366 0.0492
Brugia malayi RE15519p 0.0092 0.1 0.1139
Echinococcus granulosus g protein coupled receptor 0.0092 0.1 0.1346
Onchocerca volvulus 0.0092 0.1 0.1
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Onchocerca volvulus 0.0092 0.1 0.1
Echinococcus multilocularis serotonin receptor 0.0092 0.1 0.1346
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0048 0.0366 0.5
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0092 0.1 0.1346
Echinococcus granulosus neuropeptide receptor 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0092 0.1 0.1346
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.1 0.1346
Echinococcus granulosus neuropeptide s receptor 0.0092 0.1 0.1346
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0092 0.1 0.1139
Echinococcus multilocularis allatostatin A receptor 0.0092 0.1 0.1346
Echinococcus granulosus tm gpcr rhodopsin 0.0092 0.1 0.1346
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0071 1
Brugia malayi GnHR receptor homolog 0.0092 0.1 0.1139
Loa Loa (eye worm) neuropeptide F receptor 0.0092 0.1 0.1139
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0092 0.1 0.1346
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0366 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0366 1
Schistosoma mansoni hypothetical protein 0.0092 0.1 0.1346
Echinococcus multilocularis neuropeptide receptor 0.0092 0.1 0.1346
Echinococcus multilocularis dro:myosuppressin receptor 0.0092 0.1 0.1346
Trichomonas vaginalis set domain proteins, putative 0.0731 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.1 0.1346
Echinococcus granulosus histone lysine methyltransferase setb 0.0108 0.122 0.1641
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0071 0.0096
Schistosoma mansoni amine GPCR 0.0092 0.1 0.1346
Schistosoma mansoni histamine h1 receptor 0.0092 0.1 0.1346
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0048 0.0366 0.0492
Echinococcus granulosus biogenic amine 5HT receptor 0.0092 0.1 0.1346
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0108 0.122 0.1641
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Loa Loa (eye worm) TYRA-2 protein 0.0092 0.1 0.1139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Brugia malayi AKH receptor 0.0092 0.1 0.1139
Echinococcus multilocularis neuropeptide Y receptor 0.0092 0.1 0.1346
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.1 0.1346
Brugia malayi sulfakinin receptor protein 0.0092 0.1 0.1139
Loa Loa (eye worm) melatonin receptor type 1A 0.0092 0.1 0.1139
Brugia malayi neuropeptide F receptor 0.0092 0.1 0.1139
Brugia malayi hypothetical protein 0.0092 0.1 0.1139
Brugia malayi hypothetical protein 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.1 0.1346
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0092 0.1 0.1346
Echinococcus granulosus 7tm_1 domain containing protein 0.0092 0.1 0.1346
Echinococcus multilocularis neuropeptides capa receptor 0.0092 0.1 0.1346
Echinococcus multilocularis neuropeptide s receptor 0.0092 0.1 0.1346
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0092 0.1 0.1
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0092 0.1 0.1139
Brugia malayi Serotonin receptor 0.0092 0.1 0.1139
Echinococcus granulosus flap endonuclease 1 0.0027 0.0071 0.0096
Onchocerca volvulus 0.0092 0.1 0.1
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Echinococcus granulosus dro:myosuppressin receptor 0.0092 0.1 0.1346
Brugia malayi hypothetical protein 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Onchocerca volvulus 0.0092 0.1 0.1
Brugia malayi larval opioid receptor 0.0092 0.1 0.1139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.1 0.1346
Schistosoma mansoni biogenic amine (5HT) receptor 0.0092 0.1 0.1346
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0092 0.1 0.1346
Echinococcus granulosus fmrfamide receptor 0.0092 0.1 0.1346
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0048 0.0366 0.0492
Echinococcus granulosus G protein coupled receptor 139 0.0092 0.1 0.1346
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0366 0.0492
Brugia malayi G-protein coupled receptor 0.0092 0.1 0.1139
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0092 0.1 0.1346
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0092 0.1 0.1346
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0092 0.1 0.1346
Onchocerca volvulus 0.0092 0.1 0.1
Echinococcus multilocularis isocitrate dehydrogenase 0.0048 0.0366 0.0492
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0108 0.122 0.1641
Schistosoma mansoni neuropeptide receptor 0.0092 0.1 0.1346
Brugia malayi putative neuropeptide receptor 0.0092 0.1 0.1139
Schistosoma mansoni amine GPCR 0.0092 0.1 0.1346
Echinococcus granulosus neuropeptide receptor A26 0.0092 0.1 0.1346
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0092 0.1 0.1139
Onchocerca volvulus 0.0092 0.1 0.1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0092 0.1 0.1346
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0071 0.0096
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.1 0.1346
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0108 0.122 0.1641
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0048 0.0366 0.0492
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Plasmodium vivax SET domain protein, putative 0.0108 0.122 0.1641
Echinococcus multilocularis serotonin receptor 0.0092 0.1 0.1346
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0092 0.1 0.1346
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0071 0.1951
Schistosoma mansoni hypothetical protein 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.1 0.1346
Schistosoma mansoni hypothetical protein 0.0092 0.1 0.1346
Onchocerca volvulus 0.0092 0.1 0.1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0092 0.1 0.1346
Onchocerca volvulus 0.0092 0.1 0.1
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0366 0.0492
Echinococcus multilocularis G protein coupled receptor 139 0.0092 0.1 0.1346
Schistosoma mansoni growth hormone secretagogue receptor 0.0092 0.1 0.1346
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.1 0.1346
Onchocerca volvulus 0.0092 0.1 0.1
Echinococcus granulosus tm gpcr rhodopsin 0.0092 0.1 0.1346
Echinococcus multilocularis neuropeptides capa receptor 0.0092 0.1 0.1346
Plasmodium falciparum SET domain protein, putative 0.0548 0.743 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0092 0.1 0.1346
Schistosoma mansoni hypothetical protein 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Schistosoma mansoni neuropeptide receptor 0.0092 0.1 0.1346
Schistosoma mansoni opsin-like receptor 0.0092 0.1 0.1346
Echinococcus granulosus serotonin receptor 0.0092 0.1 0.1346
Echinococcus multilocularis neuropeptide Y receptor 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Schistosoma mansoni amine GPCR 0.0092 0.1 0.1346
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0048 0.0366 1
Schistosoma mansoni opsin-like receptor 0.0092 0.1 0.1346
Schistosoma mansoni alpha-1 adrenergic receptor 0.0092 0.1 0.1346
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0366 0.0492
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0071 0.1951
Brugia malayi hypothetical protein 0.0092 0.1 0.1139
Brugia malayi putative neuropeptide receptor NPR1 0.0092 0.1 0.1139
Onchocerca volvulus 0.0092 0.1 0.1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0092 0.1 0.1346
Echinococcus granulosus neuropeptide FF receptor 2 0.0092 0.1 0.1346
Brugia malayi hypothetical protein 0.0092 0.1 0.1139
Brugia malayi hypothetical protein 0.0092 0.1 0.1139
Echinococcus granulosus g-protein coupled receptor 0.0092 0.1 0.1346
Echinococcus granulosus tachykinin peptides receptor 99D 0.0092 0.1 0.1346
Echinococcus granulosus tm gpcr rhodopsin 0.0092 0.1 0.1346
Echinococcus granulosus biogenic amine 5HT receptor 0.0092 0.1 0.1346
Schistosoma mansoni histone-lysine n-methyltransferase seto7 0.0548 0.743 1
Onchocerca volvulus 0.0092 0.1 0.1
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0071 0.0081
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0366 0.0492
Echinococcus multilocularis fmrfamide receptor 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0108 0.122 0.1389
Schistosoma mansoni neuropeptide F-like receptor 0.0092 0.1 0.1346
Echinococcus granulosus hypothetical protein 0.0092 0.1 0.1346
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0092 0.1 0.1346
Echinococcus multilocularis histone lysine n methyltransferase setd8 0.0548 0.743 1
Echinococcus granulosus somatostatin receptor 0.0092 0.1 0.1346
Plasmodium vivax SET domain protein, putative 0.0548 0.743 1
Brugia malayi Pre-SET motif family protein 0.0644 0.878 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.1 0.1346
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Schistosoma mansoni neuropeptide receptor 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0644 0.878 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Onchocerca volvulus 0.0092 0.1 0.1
Loa Loa (eye worm) G-protein coupled receptor 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Brugia malayi Protein set-1 0.0548 0.743 0.8462
Echinococcus granulosus sex peptide receptor 0.0092 0.1 0.1346
Schistosoma mansoni neuropeptide f receptor 76f 0.0092 0.1 0.1346
Echinococcus multilocularis g-protein coupled receptor 0.0092 0.1 0.1346
Echinococcus granulosus neuropeptide receptor 0.0092 0.1 0.1346
Loa Loa (eye worm) G-protein coupled receptor 0.0092 0.1 0.1139
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0092 0.1 0.1346
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0048 0.0366 1
Echinococcus multilocularis neuropeptide receptor A26 0.0092 0.1 0.1346
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0092 0.1 0.1346
Echinococcus granulosus g protein coupled receptor 0.0092 0.1 0.1346
Echinococcus multilocularis g protein coupled receptor 0.0092 0.1 0.1346
Echinococcus granulosus alpha 1A adrenergic receptor 0.0092 0.1 0.1346
Echinococcus granulosus g protein coupled receptor 0.0092 0.1 0.1346
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0092 0.1 0.1346
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.1 0.1346
Echinococcus granulosus histone lysine n methyltransferase setd8 0.0548 0.743 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0048 0.0366 0.0417
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0092 0.1 0.1346
Echinococcus granulosus orexin receptor type 2 0.0092 0.1 0.1346
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0086 0.0915 0.1232
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.1 0.1346
Brugia malayi hypothetical protein 0.0092 0.1 0.1139
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0108 0.122 0.1641
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Plasmodium falciparum flap endonuclease 1 0.0027 0.0071 0.0096
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0092 0.1 0.1139
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Schistosoma mansoni amine GPCR 0.0092 0.1 0.1346
Schistosoma mansoni amine GPCR 0.0092 0.1 0.1346
Onchocerca volvulus 0.0108 0.122 0.122
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0092 0.1 0.1346
Brugia malayi hypothetical protein 0.0092 0.1 0.1139
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0092 0.1 0.1346
Echinococcus multilocularis g protein coupled receptor 0.0092 0.1 0.1346
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0071 1
Echinococcus multilocularis neuropeptide receptor 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.1 0.1346
Brugia malayi Isocitrate dehydrogenase 0.0048 0.0366 0.0417
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Onchocerca volvulus 0.0092 0.1 0.1
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Echinococcus granulosus peptide allatostatin:somatostatin 0.0092 0.1 0.1346
Schistosoma mansoni flap endonuclease-1 0.0024 0.0035 0.0048
Echinococcus granulosus neuropeptide Y receptor 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Brugia malayi Dopamine receptor protein 1 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0548 0.743 0.8462
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0108 0.122 0.1641
Brugia malayi G-protein coupled receptor 0.0092 0.1 0.1139
Schistosoma mansoni biogenic amine receptor 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Schistosoma mansoni biogenic amine receptor 0.0092 0.1 0.1346
Echinococcus granulosus 7TM GPCR rhodopsin 0.0092 0.1 0.1346
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0108 0.122 0.1641
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0366 1
Brugia malayi follicle stimulating hormone receptor 0.0092 0.1 0.1139
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.1 0.1346
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Schistosoma mansoni myosin xvIII 0.0092 0.1 0.1346
Echinococcus multilocularis somatostatin receptor 0.0092 0.1 0.1346
Echinococcus granulosus neuropeptides capa receptor 0.0092 0.1 0.1346
Echinococcus multilocularis orexin receptor type 2 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0071 0.0096
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.1 0.1346
Brugia malayi G protein-coupled receptor F59B2.13 0.0092 0.1 0.1139
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0092 0.1 0.1346
Chlamydia trachomatis hypothetical protein 0.0022 0 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.1 0.1346
Schistosoma mansoni opsin-like receptor 0.0092 0.1 0.1346
Schistosoma mansoni neuropeptide F-like receptor 0.0092 0.1 0.1346
Echinococcus multilocularis neuropeptide FF receptor 2 0.0092 0.1 0.1346
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0092 0.1 0.1346
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0092 0.1 0.1346
Brugia malayi Flap endonuclease-1 0.0027 0.0071 0.0081
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Brugia malayi hypothetical protein 0.0092 0.1 0.1139
Echinococcus multilocularis fmrfamide receptor 0.0092 0.1 0.1346
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0092 0.1 0.1346
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Echinococcus multilocularis G-protein coupled receptor, putative 0.0092 0.1 0.1346
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0092 0.1 0.1346
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0092 0.1 0.1139
Brugia malayi Dopamine receptor 0.0092 0.1 0.1139
Loa Loa (eye worm) hypothetical protein 0.0092 0.1 0.1139
Brugia malayi neuropeptide F receptor 0.0092 0.1 0.1139
Onchocerca volvulus 0.0092 0.1 0.1
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0071 0.1951
Onchocerca volvulus 0.0092 0.1 0.1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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