Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | endonuclease G, putative | 0.0043 | 0.1907 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0071 | 0.3981 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Echinococcus multilocularis | Endonuclease G | 0.0043 | 0.1907 | 0.4157 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Onchocerca volvulus | 0.0154 | 1 | 1 | |
Trypanosoma brucei | endonuclease G, putative | 0.0043 | 0.1907 | 0.5 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0023 | 0.0431 | 0.0299 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0071 | 0.3981 | 1 |
Leishmania major | endonuclease G, putative | 0.0043 | 0.1907 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0071 | 0.3981 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0071 | 0.3981 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0154 | 1 | 1 |
Echinococcus granulosus | ectonucleotide | 0.006 | 0.3164 | 0.7698 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.3981 | 0.3898 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0071 | 0.3981 | 1 |
Onchocerca volvulus | 0.0071 | 0.3981 | 0.371 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Echinococcus multilocularis | ectonucleotide | 0.006 | 0.3164 | 0.7698 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0071 | 0.3981 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0071 | 0.3981 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0023 | 0.0431 | 0.0299 |
Trypanosoma brucei | endonuclease G, putative | 0.0043 | 0.1907 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Trypanosoma brucei | endonuclease G, putative | 0.0043 | 0.1907 | 0.5 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0071 | 0.3981 | 0.371 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0071 | 0.3981 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0071 | 0.3981 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.006 | 0.3164 | 0.7698 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0071 | 0.3981 | 0.371 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0071 | 0.3981 | 1 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0071 | 0.3981 | 0.371 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0071 | 0.3981 | 0.371 |
Brugia malayi | endonuclease G, mitochondrial precursor | 0.0043 | 0.1907 | 0.1542 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.006 | 0.3164 | 0.7698 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0071 | 0.3981 | 0.371 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Echinococcus granulosus | Endonuclease G | 0.0043 | 0.1907 | 0.4157 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Schistosoma mansoni | hypothetical protein | 0.0154 | 1 | 1 |
Schistosoma mansoni | endonuclease related | 0.0043 | 0.1907 | 0.1542 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Onchocerca volvulus | 0.0071 | 0.3981 | 0.371 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Leishmania major | DNA/RNA non-specific endonuclease-like protein | 0.0043 | 0.1907 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.3981 | 0.3898 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.3981 | 0.3898 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.3164 | 0.3069 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0023 | 0.0431 | 0.0299 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0043 | 0.1907 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Trypanosoma cruzi | endonuclease G, putative | 0.0043 | 0.1907 | 0.5 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0071 | 0.3981 | 1 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0043 | 0.1907 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0023 | 0.0431 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Toxoplasma gondii | DNA/RNA non-specific endonuclease | 0.0043 | 0.1907 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0431 | 0.0299 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.