Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.3425 | 0.3425 |
Giardia lamblia | Phosphatidylinositol-glycan biosynthesis, class O protein | 0.0026 | 0 | 0.5 |
Trypanosoma brucei | endonuclease G, putative | 0.01 | 0.2216 | 1 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0167 | 0.4211 | 0.4211 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0167 | 0.4211 | 0.4211 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0167 | 0.4211 | 0.4211 |
Trypanosoma brucei | endonuclease G, putative | 0.01 | 0.2216 | 1 |
Trypanosoma cruzi | endonuclease G, putative | 0.01 | 0.2216 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.036 | 1 | 1 |
Schistosoma mansoni | endonuclease related | 0.01 | 0.2216 | 0.2216 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.036 | 1 | 1 |
Echinococcus granulosus | Endonuclease G | 0.01 | 0.2216 | 0.5262 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0167 | 0.4211 | 0.4211 |
Echinococcus multilocularis | Endonuclease G | 0.01 | 0.2216 | 0.5262 |
Mycobacterium leprae | hypothetical protein | 0.0026 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.4211 | 0.4211 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0167 | 0.4211 | 0.4211 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0 | 0.5 |
Trypanosoma brucei | endonuclease G, putative | 0.01 | 0.2216 | 1 |
Entamoeba histolytica | phosphatidylinositol-glycan biosynthesis class O protein, putative | 0.0026 | 0 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0167 | 0.4211 | 1 |
Echinococcus granulosus | ectonucleotide | 0.014 | 0.3425 | 0.8134 |
Trypanosoma cruzi | endonuclease G, putative | 0.01 | 0.2216 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0167 | 0.4211 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0167 | 0.4211 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.4211 | 0.4211 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0167 | 0.4211 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0167 | 0.4211 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0167 | 0.4211 | 1 |
Onchocerca volvulus | 0.036 | 1 | 1 | |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0167 | 0.4211 | 1 |
Plasmodium falciparum | GPI ethanolamine phosphate transferase 3, putative | 0.0026 | 0 | 0.5 |
Leishmania major | DNA/RNA non-specific endonuclease-like protein | 0.01 | 0.2216 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0167 | 0.4211 | 1 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.01 | 0.2216 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.014 | 0.3425 | 0.8134 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0167 | 0.4211 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0167 | 0.4211 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.014 | 0.3425 | 0.8134 |
Leishmania major | endonuclease G, putative | 0.01 | 0.2216 | 1 |
Onchocerca volvulus | 0.0167 | 0.4211 | 0.4211 | |
Onchocerca volvulus | 0.0167 | 0.4211 | 0.4211 | |
Brugia malayi | endonuclease G, mitochondrial precursor | 0.01 | 0.2216 | 0.2216 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.4211 | 0.4211 |
Echinococcus multilocularis | ectonucleotide | 0.014 | 0.3425 | 0.8134 |
Entamoeba histolytica | phosphatidylinositol-glycan biosynthesis class O protein, putative | 0.0026 | 0 | 0.5 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.01 | 0.2216 | 0.5 |
Toxoplasma gondii | DNA/RNA non-specific endonuclease | 0.01 | 0.2216 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0167 | 0.4211 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.