Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Cathepsin L-like precursor | 0.0096 | 0.2609 | 0.2609 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0141 | 0.4834 | 1 |
Plasmodium vivax | unspecified product | 0.0076 | 0.1571 | 0.325 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.4834 | 1 |
Onchocerca volvulus | 0.0141 | 0.4834 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.2609 | 0.2609 |
Onchocerca volvulus | 0.0141 | 0.4834 | 1 | |
Loa Loa (eye worm) | ctsf protein | 0.0141 | 0.4834 | 0.4834 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0076 | 0.1571 | 0.1571 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0141 | 0.4834 | 0.3871 |
Echinococcus multilocularis | cysteine protease | 0.0141 | 0.4834 | 0.3871 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Echinococcus granulosus | cathepsin b | 0.0244 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.4834 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.4834 | 0.4834 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0141 | 0.4834 | 0.3871 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.4834 | 0.4834 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.4834 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0141 | 0.4834 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0141 | 0.4834 | 0.4834 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0141 | 0.4834 | 0.3871 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0096 | 0.2609 | 0.2609 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0141 | 0.4834 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0097 | 0.2642 | 0.328 |
Brugia malayi | Cathepsin L-like precursor | 0.0141 | 0.4834 | 0.4834 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0076 | 0.1571 | 0.1571 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0097 | 0.2642 | 0.2642 |
Brugia malayi | Cathepsin L-like precursor | 0.0141 | 0.4834 | 0.4834 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0076 | 0.1571 | 0.1571 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.4834 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0096 | 0.2609 | 0.2609 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.4834 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0097 | 0.2642 | 0.2642 |
Brugia malayi | Cathepsin L-like precursor | 0.0141 | 0.4834 | 0.4834 |
Giardia lamblia | Cathepsin B precursor | 0.0097 | 0.2642 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0141 | 0.4834 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0076 | 0.1571 | 0.1571 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0141 | 0.4834 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0141 | 0.4834 | 0.4834 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0097 | 0.2642 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.4834 | 1 |
Echinococcus granulosus | cathepsin b | 0.0244 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0096 | 0.2609 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0141 | 0.4834 | 0.3871 |
Onchocerca volvulus | 0.0141 | 0.4834 | 1 | |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0141 | 0.4834 | 0.4834 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0076 | 0.1571 | 0.1571 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0244 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0244 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0076 | 0.1571 | 0.1571 |
Plasmodium vivax | vivapain-2 | 0.0141 | 0.4834 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0244 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0141 | 0.4834 | 0.4834 |
Brugia malayi | Cathepsin L-like precursor | 0.0141 | 0.4834 | 0.4834 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0244 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0096 | 0.2609 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0141 | 0.4834 | 0.4834 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0097 | 0.2642 | 0.2642 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.4834 | 0.4834 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Onchocerca volvulus | 0.0141 | 0.4834 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.2609 | 0.2609 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0141 | 0.4834 | 0.4834 |
Plasmodium vivax | vivapain-3 | 0.0076 | 0.1571 | 0.325 |
Trypanosoma cruzi | cysteine protease, putative | 0.0076 | 0.1571 | 0.1571 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0141 | 0.4834 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.4834 | 0.4834 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.2609 | 0.2609 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.4834 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0141 | 0.4834 | 0.4834 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0096 | 0.2609 | 0.2609 |
Brugia malayi | cathepsin L-like precursor | 0.0096 | 0.2609 | 0.2609 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.4834 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.4834 | 1 |
Plasmodium vivax | vivapain-1 | 0.0076 | 0.1571 | 0.325 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0141 | 0.4834 | 0.4834 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0141 | 0.4834 | 0.4834 |
Onchocerca volvulus | 0.0141 | 0.4834 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.4834 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.4834 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0141 | 0.4834 | 0.3871 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Onchocerca volvulus | 0.0141 | 0.4834 | 1 | |
Plasmodium vivax | vivapain-2 | 0.0141 | 0.4834 | 1 |
Onchocerca volvulus | 0.0141 | 0.4834 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.4834 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0076 | 0.1571 | 0.1571 |
Loa Loa (eye worm) | fibroinase | 0.0141 | 0.4834 | 0.4834 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0096 | 0.2609 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0097 | 0.2642 | 0.328 |
Leishmania major | cysteine peptidase A (CPA) | 0.0141 | 0.4834 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.4834 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0141 | 0.4834 | 0.3871 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0096 | 0.2609 | 0.2609 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.4834 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0244 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.4834 | 0.4834 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0244 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0141 | 0.4834 | 0.3871 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0076 | 0.1571 | 0.1571 |
Echinococcus multilocularis | cathepsin b | 0.0244 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0096 | 0.2609 | 0.1232 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0141 | 0.4834 | 0.3871 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0076 | 0.1571 | 0.1571 |
Onchocerca volvulus | Cathepsin L homolog | 0.0141 | 0.4834 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0141 | 0.4834 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0141 | 0.4834 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0097 | 0.2642 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0141 | 0.4834 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.