Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0231 | 0.5172 |
Plasmodium falciparum | peptide deformylase | 0.1901 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0214 | 0.4542 |
Toxoplasma gondii | hypothetical protein | 0.1901 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0214 | 0.4542 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0084 | 0.0276 | 0.4155 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0222 | 0.4828 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0051 | 0.0096 | 0.2636 |
Brugia malayi | Peptidase family M13 containing protein | 0.0101 | 0.0362 | 1 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0101 | 0.0362 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0231 | 0.5172 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0073 | 0.0214 | 0.4542 |
Loa Loa (eye worm) | carboxylesterase | 0.0073 | 0.0214 | 0.4542 |
Brugia malayi | Matrixin family protein | 0.0056 | 0.0124 | 0.343 |
Mycobacterium ulcerans | peptide deformylase | 0.1901 | 1 | 1 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0074 | 0.0222 | 0.4828 |
Trypanosoma brucei | Peptide deformylase 2 | 0.0725 | 0.3707 | 0.5 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0101 | 0.0362 | 1 |
Onchocerca volvulus | Matrilysin homolog | 0.0051 | 0.0099 | 1 |
Loa Loa (eye worm) | matrixin family protein | 0.0056 | 0.0124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0362 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0222 | 0.4828 |
Loa Loa (eye worm) | matrixin family protein | 0.0051 | 0.0099 | 0.0325 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0725 | 0.3707 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0725 | 0.3707 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0725 | 0.3707 | 0.5 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0101 | 0.0362 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0231 | 0.5172 |
Brugia malayi | Carboxylesterase family protein | 0.0073 | 0.0214 | 0.5907 |
Onchocerca volvulus | 0.005 | 0.0091 | 0.9112 | |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 0.1901 | 1 | 1 |
Plasmodium vivax | peptide deformylase, putative | 0.1901 | 1 | 0.5 |
Treponema pallidum | polypeptide deformylase (def) | 0.1901 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 0.1901 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0222 | 0.4828 |
Leishmania major | polypeptide deformylase-like protein, putative | 0.0725 | 0.3707 | 0.5 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0051 | 0.0096 | 0.2636 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0074 | 0.0222 | 0.4828 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0051 | 0.0099 | 1 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0101 | 0.0362 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0222 | 0.4828 |
Schistosoma mansoni | Nep2 peptidase (M13 family) | 0.0051 | 0.0096 | 0.2636 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0084 | 0.0276 | 0.4155 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 0.1901 | 1 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0725 | 0.3707 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0231 | 0.5172 |
Schistosoma mansoni | neprilysin-2 (M13 family) | 0.0051 | 0.0096 | 0.2636 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.0725 | 0.3707 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0231 | 0.5172 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0073 | 0.0214 | 0.5907 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0362 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0362 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0073 | 0.0214 | 0.5907 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0231 | 0.5172 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0051 | 0.0096 | 0.2636 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.