Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE AMIDASE AMIC (AMINOHYDROLASE) | 0.0076 | 0 | 0.5 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0165 | 0.1366 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.063 | 0.8503 | 0.8503 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0165 | 0.1366 | 1 |
Schistosoma mansoni | amidase | 0.063 | 0.8503 | 1 |
Onchocerca volvulus | 0.0727 | 1 | 0.5 | |
Trypanosoma brucei | lipase domain protein, putative | 0.0727 | 1 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.063 | 0.8503 | 0.8503 |
Loa Loa (eye worm) | lipase | 0.0727 | 1 | 1 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.063 | 0.8503 | 1 |
Echinococcus granulosus | sn1 specific diacylglycerol lipase beta | 0.0727 | 1 | 1 |
Plasmodium vivax | glutamyl-tRNA(Gln) amidotransferase subunit A, putative | 0.0076 | 0 | 0.5 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.063 | 0.8503 | 0.8503 |
Trichomonas vaginalis | lipase containing protein, putative | 0.0727 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) | 0.0076 | 0 | 0.5 |
Trichomonas vaginalis | lipase containing protein, putative | 0.0727 | 1 | 0.5 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0076 | 0 | 0.5 |
Plasmodium falciparum | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0076 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0727 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.063 | 0.8503 | 0.8503 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0076 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0727 | 1 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.063 | 0.8503 | 0.8503 |
Echinococcus multilocularis | sn1 specific diacylglycerol lipase beta | 0.0727 | 1 | 1 |
Brugia malayi | amidase | 0.063 | 0.8503 | 0.8503 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0076 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0727 | 1 | 1 |
Trypanosoma brucei | lipase domain protein, putative | 0.0727 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.