Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | lipase containing protein, putative | 0.072 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) | 0.0075 | 0 | 0.5 |
Trichomonas vaginalis | lipase containing protein, putative | 0.072 | 1 | 0.5 |
Plasmodium vivax | glutamyl-tRNA(Gln) amidotransferase subunit A, putative | 0.0075 | 0 | 0.5 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0623 | 0.8497 | 0.8497 |
Echinococcus granulosus | sn1 specific diacylglycerol lipase beta | 0.072 | 1 | 1 |
Trypanosoma brucei | lipase domain protein, putative | 0.072 | 1 | 1 |
Loa Loa (eye worm) | lipase | 0.072 | 1 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0623 | 0.8497 | 0.8497 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0623 | 0.8497 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0163 | 0.1358 | 1 |
Schistosoma mansoni | amidase | 0.0623 | 0.8497 | 1 |
Onchocerca volvulus | 0.072 | 1 | 0.5 | |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0623 | 0.8497 | 0.8497 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0163 | 0.1358 | 1 |
Mycobacterium leprae | PROBABLE AMIDASE AMIC (AMINOHYDROLASE) | 0.0075 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.072 | 1 | 1 |
Trypanosoma brucei | lipase domain protein, putative | 0.072 | 1 | 1 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0075 | 0 | 0.5 |
Brugia malayi | amidase | 0.0623 | 0.8497 | 0.8497 |
Echinococcus multilocularis | sn1 specific diacylglycerol lipase beta | 0.072 | 1 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0623 | 0.8497 | 0.8497 |
Loa Loa (eye worm) | hypothetical protein | 0.0623 | 0.8497 | 0.8497 |
Leishmania major | hypothetical protein, conserved | 0.072 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0075 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.072 | 1 | 1 |
Plasmodium falciparum | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0075 | 0 | 0.5 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0075 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.