Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | cathepsin L-like protease | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0106 | 0.3698 | 0.6579 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0171 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0106 | 0.3698 | 0.3698 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0126 | 0.562 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0126 | 0.562 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0126 | 0.562 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0086 | 0.1788 | 0.1788 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.3698 | 0.3403 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.0106 | 0.3698 | 0.6579 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0126 | 0.562 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0171 | 1 | 1 |
Onchocerca volvulus | 0.0126 | 0.562 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0106 | 0.3698 | 0.6284 |
Leishmania major | cathepsin L-like protease | 0.0126 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0126 | 0.562 | 1 |
Onchocerca volvulus | 0.0126 | 0.562 | 1 | |
Brugia malayi | eukaryotic initiation factor 4A | 0.0106 | 0.3698 | 0.3698 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.1788 | 0.1788 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Plasmodium vivax | RNA helicase-1, putative | 0.0106 | 0.3698 | 0.6579 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0171 | 1 | 1 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0106 | 0.3698 | 0.6579 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0106 | 0.3698 | 0.6284 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1788 | 0.1405 |
Brugia malayi | cathepsin L-like precursor | 0.0086 | 0.1788 | 0.1788 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0126 | 0.562 | 0.562 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0126 | 0.562 | 0.5415 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0171 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.562 | 0.5415 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0072 | 0.0446 | 0.0794 |
Onchocerca volvulus | 0.0126 | 0.562 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Onchocerca volvulus | 0.0126 | 0.562 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0126 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0171 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0126 | 0.562 | 0.562 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.0106 | 0.3698 | 0.6284 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0086 | 0.1788 | 0.1788 |
Plasmodium vivax | vivapain-2 | 0.0126 | 0.562 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0126 | 0.562 | 1 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0106 | 0.3698 | 0.3698 |
Brugia malayi | Cathepsin L-like precursor | 0.0126 | 0.562 | 0.562 |
Echinococcus granulosus | cathepsin l1 | 0.0126 | 0.562 | 0.562 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0126 | 0.562 | 0.562 |
Onchocerca volvulus | 0.0126 | 0.562 | 1 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0126 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0126 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0126 | 0.562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1788 | 0.1405 |
Echinococcus multilocularis | cysteine protease | 0.0126 | 0.562 | 0.562 |
Echinococcus granulosus | cathepsin b | 0.0171 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0126 | 0.562 | 0.562 |
Loa Loa (eye worm) | cysteine protease | 0.0126 | 0.562 | 0.5415 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.1788 | 0.3182 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0126 | 0.562 | 0.5415 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0086 | 0.1788 | 0.1788 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0126 | 0.562 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0126 | 0.562 | 0.562 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0126 | 0.562 | 0.562 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0126 | 0.562 | 0.562 |
Echinococcus multilocularis | cathepsin b | 0.0171 | 1 | 1 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.0106 | 0.3698 | 1 |
Leishmania major | cathepsin L-like protease | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0126 | 0.562 | 0.562 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0126 | 0.562 | 0.562 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0086 | 0.1788 | 0.1788 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.0106 | 0.3698 | 0.4983 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Leishmania major | cathepsin L-like protease | 0.0126 | 0.562 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0126 | 0.562 | 1 |
Plasmodium vivax | vivapain-2 | 0.0126 | 0.562 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0126 | 0.562 | 0.562 |
Leishmania major | cathepsin L-like protease | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0106 | 0.3698 | 0.6579 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0106 | 0.3698 | 0.3698 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0126 | 0.562 | 0.562 |
Onchocerca volvulus | 0.0126 | 0.562 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0126 | 0.562 | 0.562 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0106 | 0.3698 | 0.6579 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0126 | 0.562 | 0.562 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0072 | 0.0446 | 0.0446 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0106 | 0.3698 | 0.3698 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.0106 | 0.3698 | 0.6579 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0126 | 0.562 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0126 | 0.562 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0126 | 0.562 | 0.562 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0072 | 0.0446 | 0.0794 |
Treponema pallidum | ATP-dependent RNA helicase | 0.0106 | 0.3698 | 0.5 |
Loa Loa (eye worm) | fibroinase | 0.0126 | 0.562 | 0.5415 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.1788 | 0.1788 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0106 | 0.3698 | 0.3698 |
Echinococcus multilocularis | cysteine protease | 0.0126 | 0.562 | 0.562 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0126 | 0.562 | 1 |
Leishmania major | cathepsin L-like protease | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.1788 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.0126 | 0.562 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0126 | 0.562 | 0.562 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0126 | 0.562 | 0.562 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0086 | 0.1788 | 0.3182 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0106 | 0.3698 | 0.3698 |
Leishmania major | cathepsin L-like protease | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0126 | 0.562 | 0.562 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1788 | 0.1405 |
Onchocerca volvulus | 0.0126 | 0.562 | 1 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0171 | 1 | 1 |
Mycobacterium tuberculosis | Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) | 0.0106 | 0.3698 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0126 | 0.562 | 1 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0106 | 0.3698 | 0.3698 |
Echinococcus granulosus | cathepsin b | 0.0171 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0126 | 0.562 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0126 | 0.562 | 0.562 |
Brugia malayi | Cathepsin L-like precursor | 0.0126 | 0.562 | 0.562 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0106 | 0.3698 | 0.3698 |
Loa Loa (eye worm) | ctsf protein | 0.0126 | 0.562 | 0.5415 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0072 | 0.0446 | 0.0446 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0126 | 0.562 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.