Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0128 | 0.562 | 0.562 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0128 | 0.562 | 1 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0106 | 0.3567 | 0.6347 |
Onchocerca volvulus | Cathepsin L homolog | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0087 | 0.1788 | 0.1788 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0106 | 0.3567 | 0.3567 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0128 | 0.562 | 0.562 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0106 | 0.3567 | 0.3567 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0174 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0128 | 0.562 | 0.562 |
Brugia malayi | Cathepsin L-like precursor | 0.0128 | 0.562 | 0.562 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0128 | 0.562 | 0.5415 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0128 | 0.562 | 0.562 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0174 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0128 | 0.562 | 0.562 |
Plasmodium vivax | vivapain-2 | 0.0128 | 0.562 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0128 | 0.562 | 0.5415 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0087 | 0.1788 | 0.1788 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0073 | 0.0446 | 0.0446 |
Brugia malayi | Cathepsin L-like precursor | 0.0128 | 0.562 | 0.562 |
Onchocerca volvulus | 0.0128 | 0.562 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.562 | 1 |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0073 | 0.0446 | 0.0794 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.1788 | 0.1405 |
Brugia malayi | Cathepsin L-like precursor | 0.0128 | 0.562 | 0.562 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0106 | 0.3567 | 0.3567 |
Brugia malayi | Cathepsin L-like precursor | 0.0128 | 0.562 | 0.562 |
Loa Loa (eye worm) | ctsf protein | 0.0128 | 0.562 | 0.5415 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0106 | 0.3567 | 0.3567 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0128 | 0.562 | 0.562 |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.562 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0073 | 0.0446 | 0.0446 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0106 | 0.3567 | 0.6032 |
Onchocerca volvulus | 0.0128 | 0.562 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0128 | 0.562 | 0.562 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.562 | 1 |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.562 | 1 |
Onchocerca volvulus | 0.0128 | 0.562 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.562 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0128 | 0.562 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0128 | 0.562 | 0.562 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0128 | 0.562 | 0.562 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0128 | 0.562 | 0.562 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.562 | 1 |
Plasmodium vivax | vivapain-2 | 0.0128 | 0.562 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0174 | 1 | 1 |
Onchocerca volvulus | 0.0128 | 0.562 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0174 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0128 | 0.562 | 0.562 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0106 | 0.3567 | 0.3567 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0174 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0073 | 0.0446 | 0.0794 |
Leishmania major | cysteine peptidase A (CPA) | 0.0128 | 0.562 | 1 |
Mycobacterium tuberculosis | Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) | 0.0106 | 0.3567 | 0.5 |
Onchocerca volvulus | 0.0128 | 0.562 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0106 | 0.3567 | 0.6347 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Echinococcus granulosus | cathepsin b | 0.0174 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0128 | 0.562 | 0.562 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0087 | 0.1788 | 0.1788 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0106 | 0.3567 | 0.6347 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0087 | 0.1788 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0128 | 0.562 | 0.562 |
Loa Loa (eye worm) | fibroinase | 0.0128 | 0.562 | 0.5415 |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.562 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0128 | 0.562 | 0.5415 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0106 | 0.3567 | 0.3567 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Onchocerca volvulus | 0.0128 | 0.562 | 1 | |
Echinococcus granulosus | cathepsin l1 | 0.0087 | 0.1788 | 0.1788 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0174 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0128 | 0.562 | 1 |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0106 | 0.3567 | 0.3567 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0128 | 0.562 | 1 |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.3567 | 0.3266 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0128 | 0.562 | 0.562 |
Echinococcus granulosus | cathepsin l1 | 0.0128 | 0.562 | 0.562 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0087 | 0.1788 | 0.3182 |
Echinococcus granulosus | cathepsin b | 0.0174 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.562 | 1 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.0106 | 0.3567 | 0.6347 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.562 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0128 | 0.562 | 0.562 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0128 | 0.562 | 0.562 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0087 | 0.1788 | 0.1788 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.0106 | 0.3567 | 0.6347 |
Plasmodium vivax | RNA helicase-1, putative | 0.0106 | 0.3567 | 0.6347 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0106 | 0.3567 | 0.3567 |
Brugia malayi | Cathepsin L-like precursor | 0.0087 | 0.1788 | 0.1788 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.0106 | 0.3567 | 0.6032 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.1788 | 0.1405 |
Onchocerca volvulus | Cathepsin F homolog | 0.0128 | 0.562 | 1 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0106 | 0.3567 | 0.6032 |
Echinococcus multilocularis | cysteine protease | 0.0128 | 0.562 | 0.562 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Treponema pallidum | ATP-dependent RNA helicase | 0.0106 | 0.3567 | 0.5 |
Echinococcus multilocularis | cathepsin b | 0.0174 | 1 | 1 |
Brugia malayi | eukaryotic initiation factor 4A | 0.0106 | 0.3567 | 0.3567 |
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.562 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0128 | 0.562 | 1 |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.562 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0128 | 0.562 | 1 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.0106 | 0.3567 | 1 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0106 | 0.3567 | 0.6347 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.0106 | 0.3567 | 0.4642 |
Brugia malayi | Cathepsin L-like precursor | 0.0128 | 0.562 | 0.562 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.562 | 0.5415 |
Onchocerca volvulus | 0.0128 | 0.562 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.1788 | 0.1405 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0087 | 0.1788 | 0.1788 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0087 | 0.1788 | 0.3182 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.