Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.0066 | 0.0353 | 0.0353 |
Onchocerca volvulus | 0.1337 | 1 | 0.5 | |
Giardia lamblia | Kinase, CDC7 | 0.1337 | 1 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0019 | 0 | 0.5 |
Trypanosoma brucei | Mitogen-activated protein kinase 10, putative | 0.0019 | 0 | 0.5 |
Trypanosoma cruzi | Mitogen-activated protein kinase 10, putative | 0.0019 | 0 | 0.5 |
Leishmania major | serine/threonine kinase-like protein, putative | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDK9 protein kinase | 0.0058 | 0.0291 | 0.0291 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1337 | 1 | 1 |
Trypanosoma cruzi | serine/threonine protein kinase, putative | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | CDC7 protein kinase | 0.1337 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0058 | 0.0291 | 0.0291 |
Leishmania major | mitogen-activated protein kinase, putative,map kinase-like protein | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.1863 | 0.1863 |
Trypanosoma cruzi | Mitogen-activated protein kinase 10, putative | 0.0019 | 0 | 0.5 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.0058 | 0.0291 | 0.0291 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1337 | 1 | 1 |
Plasmodium vivax | cyclin dependent kinase 7 (cdk7), putative | 0.0019 | 0 | 0.5 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.0066 | 0.0353 | 0.0353 |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.0058 | 0.0291 | 0.0291 |
Onchocerca volvulus | 0.1337 | 1 | 0.5 | |
Entamoeba histolytica | protein kinase domain containing protein | 0.0058 | 0.0291 | 1 |
Brugia malayi | cyclin-dependent kinase 9 | 0.0058 | 0.0291 | 0.0291 |
Plasmodium vivax | serine/threonine protein kinase KIN, putative | 0.0019 | 0 | 0.5 |
Echinococcus multilocularis | CDC7 cell division cycle 7 | 0.1337 | 1 | 1 |
Schistosoma mansoni | kinase | 0.0058 | 0.0291 | 0.0291 |
Echinococcus granulosus | CDC7 cell division cycle 7 | 0.1337 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1337 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1337 | 1 | 1 |
Plasmodium falciparum | MO15-related protein kinase | 0.0019 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.