TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 377.221 | Formula: C18H14Cl2N2O3
H donors: 2 H acceptors: 3 LogP: 3.48 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: Clc1cc(Cl)c2c(c1)N[C@H](C[C@@H]2N1Cc2c(C1=O)cccc2)C(=O)O
InChi: 1S/C18H14Cl2N2O3/c19-10-5-12(20)16-13(6-10)21-14(18(24)25)7-15(16)22-8-9-3-1-2-4-11(9)17(22)23/h1-6,14-15,21H,7-8H2,(H,24,25)/t14-,15+/m1/s1
InChiKey: RSCKTUMRDTWUIA-CABCVRRESA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Rattus norvegicus	Glutamate (NMDA) receptor subunit zeta 1	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Echinococcus multilocularis	nmda type glutamate receptor	Get druggable targets OG5_133478	All targets in OG5_133478
Schistosoma japonicum	expressed protein	Get druggable targets OG5_133478	All targets in OG5_133478
Echinococcus granulosus	glutamate receptor NMDA	Get druggable targets OG5_133478	All targets in OG5_133478
Schistosoma japonicum	Glutamate [NMDA] receptor subunit zeta-1 precursor, putative	Get druggable targets OG5_133478	All targets in OG5_133478
Echinococcus multilocularis	glutamate receptor NMDA	Get druggable targets OG5_133478	All targets in OG5_133478
Schistosoma mansoni	glutamate receptor NMDA	Get druggable targets OG5_133478	All targets in OG5_133478
Echinococcus granulosus	nmda type glutamate receptor	Get druggable targets OG5_133478	All targets in OG5_133478
Schistosoma japonicum	Glutamate [NMDA] receptor subunit zeta-1 precursor, putative	Get druggable targets OG5_133478	All targets in OG5_133478
Echinococcus multilocularis	nmda type glutamate receptor	Get druggable targets OG5_133478	All targets in OG5_133478
Schistosoma japonicum	Glutamate [NMDA] receptor subunit zeta-1 precursor, putative	Get druggable targets OG5_133478	All targets in OG5_133478
Echinococcus granulosus	nmda type glutamate receptor	Get druggable targets OG5_133478	All targets in OG5_133478

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Drosophila melanogaster	NMDA receptor 2	Glutamate (NMDA) receptor subunit zeta 1	938 aa	878 aa	27.4 %
Drosophila melanogaster	Glutamate receptor IA	Glutamate (NMDA) receptor subunit zeta 1	938 aa	979 aa	23.7 %
Echinococcus multilocularis	glutamate (NMDA) receptor subunit	Glutamate (NMDA) receptor subunit zeta 1	938 aa	822 aa	23.2 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Entamoeba histolytica	pyruvate kinase, putative	0.0025	0.055	0.0026
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0297	1	1
Plasmodium vivax	holo-[acyl-carrier-protein] synthase, putative	0.0024	0.0525	0.336
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0297	1	1
Loa Loa (eye worm)	hypothetical protein	0.0087	0.2715	0.29
Schistosoma mansoni	cpg binding protein	0.003	0.0749	0.0803
Echinococcus multilocularis	muscleblind protein 1	0.0151	0.4945	1
Brugia malayi	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	0.0085	0.2631	0.281
Toxoplasma gondii	4'-phosphopantetheinyl transferase superfamily protein	0.0024	0.0525	0.1423
Loa Loa (eye worm)	pyruvate kinase	0.0035	0.0918	0.0973
Schistosoma mansoni	glutamate receptor kainate	0.0009	0.0012	0.0012
Echinococcus granulosus	cpg binding protein	0.0032	0.0809	0.1636
Schistosoma mansoni	pyruvate kinase	0.0035	0.0918	0.0984
Brugia malayi	Pre-SET motif family protein	0.0212	0.7058	0.7558
Brugia malayi	Pyruvate kinase, alpha/beta domain containing protein	0.0011	0.0069	0.0062
Echinococcus multilocularis	pyruvate kinase	0.0018	0.0326	0.0659
Loa Loa (eye worm)	glutaminase 2	0.0278	0.9334	1
Echinococcus granulosus	Ribosomal protein S1 RNA binding domain	0.0009	0.0012	0.0023
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0031	0.0776	0.1569
Schistosoma mansoni	hypothetical protein	0.0009	0.0012	0.0012
Giardia lamblia	Pyruvate kinase	0.0035	0.0918	0.0613
Treponema pallidum	fructose-bisphosphate aldolase	0.0297	1	1
Mycobacterium tuberculosis	holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie	0.0024	0.0525	0.0065
Schistosoma mansoni	inositol monophosphatase	0.0037	0.0998	0.1069
Echinococcus multilocularis	muscleblind protein	0.0151	0.4945	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0297	1	1
Toxoplasma gondii	inositol(myo)-1(or 4)-monophosphatase 2, putative	0.0037	0.0998	0.48
Echinococcus multilocularis	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0058	0.1722	0.3483
Plasmodium falciparum	pyruvate kinase	0.0035	0.0918	1
Echinococcus multilocularis	pyruvate kinase	0.0035	0.0918	0.1857
Mycobacterium tuberculosis	Probable fructose-bisphosphate aldolase Fba	0.0145	0.4732	1
Echinococcus granulosus	Glutamate receptor ionotropic kainate 2	0.0014	0.0171	0.0346
Brugia malayi	F/Y-rich N-terminus family protein	0.001	0.006	0.0052
Echinococcus multilocularis	glutamate receptor NMDA	0.0095	0.3	0.6067
Echinococcus granulosus	Glutamate receptor ionotropic kainate 2	0.0014	0.0171	0.0346
Onchocerca volvulus	Pyruvate kinase homolog	0.0035	0.0918	0.0231
Echinococcus multilocularis	L aminoadipate semialdehyde	0.0085	0.2631	0.532
Echinococcus multilocularis	Ribosomal protein S1, RNA binding domain	0.0009	0.0012	0.0023
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0047	0.1313	0.2655
Echinococcus multilocularis	glutamate receptor subunit protein glur	0.0009	0.0012	0.0023
Onchocerca volvulus		0.0031	0.0776	0.0036
Chlamydia trachomatis	holo [acyl-carrier protein] synthase	0.0024	0.0525	0.0656
Mycobacterium tuberculosis	Probable pyruvate kinase PykA	0.0035	0.0918	0.0994
Mycobacterium ulcerans	4'-phosphopantetheinyl transferase	0.0024	0.0525	0.0031
Echinococcus multilocularis	Glutamate receptor, ionotropic kainate 2	0.0014	0.0171	0.0346
Trichomonas vaginalis	set domain proteins, putative	0.0242	0.8071	0.7876
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0031	0.0776	0.0831
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0047	0.1313	0.1396
Loa Loa (eye worm)	inositol-1	0.0037	0.0998	0.1058
Brugia malayi	Pyruvate kinase, muscle isozyme	0.0035	0.0918	0.0973
Echinococcus granulosus	histone lysine methyltransferase setb	0.0031	0.0776	0.1569
Echinococcus multilocularis	Glutamate receptor, ionotropic kainate 2	0.0014	0.0171	0.0346
Echinococcus multilocularis	pyruvate kinase	0.0035	0.0918	0.1857
Echinococcus granulosus	pyruvate kinase	0.0035	0.0918	0.1857
Schistosoma mansoni	aminoadipate-semialdehyde dehydrogenase	0.0085	0.2631	0.2818
Trichomonas vaginalis	inositol monophosphatase, putative	0.0037	0.0998	0.0087
Entamoeba histolytica	Acid sphingomyelinase-like phosphodiesterase, putative	0.0087	0.2715	0.2312
Entamoeba histolytica	Acid sphingomyelinase-like phosphodiesterase, putative	0.0087	0.2715	0.2312
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0058	0.1725	1
Loa Loa (eye worm)	pyruvate kinase	0.0035	0.0918	0.0973
Mycobacterium ulcerans	fructose-bisphosphate aldolase	0.0145	0.4732	0.4792
Schistosoma mansoni	glutamate receptor AMPA	0.0009	0.0012	0.0012
Brugia malayi	Muscleblind-like protein	0.0151	0.4945	0.5292
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0031	0.0776	0.0831
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0998	1
Echinococcus granulosus	pyruvate kinase	0.0035	0.0918	0.1857
Echinococcus granulosus	nmda type glutamate receptor	0.0127	0.4107	0.8306
Mycobacterium ulcerans	extragenic suppressor protein SuhB	0.0037	0.0998	0.0566
Plasmodium vivax	SET domain protein, putative	0.0031	0.0776	0.7593
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0776	0.082
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0058	0.1722	0.2893
Schistosoma mansoni	glutaminase	0.0278	0.9334	1
Loa Loa (eye worm)	pyruvate kinase	0.0035	0.0918	0.0973
Schistosoma mansoni	glutamate receptor NMDA	0.0109	0.347	0.3718
Toxoplasma gondii	pyruvate kinase PyK1	0.0035	0.0918	0.4234
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.0037	0.0998	0.0087
Echinococcus multilocularis	nmda type glutamate receptor	0.0127	0.4107	0.8306
Trypanosoma brucei	inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0998	1
Echinococcus granulosus	glutamate receptor subunit protein glur	0.0009	0.0012	0.0023
Loa Loa (eye worm)	hypothetical protein	0.0085	0.2631	0.281
Schistosoma mansoni	cpg binding protein	0.0032	0.0809	0.0867
Loa Loa (eye worm)	3-hydroxyacyl-CoA dehydrogenase type II	0.0054	0.1586	0.1689
Schistosoma mansoni	glutamate receptor NMDA	0.0009	0.0012	0.0012
Brugia malayi	CXXC zinc finger family protein	0.003	0.0749	0.0791
Brugia malayi	Pre-SET motif family protein	0.0031	0.0776	0.082
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0031	0.0776	0.0831
Onchocerca volvulus		0.0242	0.8071	1
Schistosoma mansoni	3-hydroxyacyl-CoA dehydrogenase	0.0058	0.1722	0.1845
Echinococcus multilocularis	glutamate receptor 2	0.0014	0.0171	0.0346
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0918	0.0973
Loa Loa (eye worm)	histone methyltransferase	0.001	0.0064	0.0056
Echinococcus granulosus	Glutamate receptor ionotropic kainate 2	0.0014	0.0171	0.0346
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.0297	1	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0297	1	1
Loa Loa (eye worm)	pyruvate kinase-PB	0.0025	0.055	0.0578
Trypanosoma brucei	pyruvate kinase 1	0.0035	0.0918	0.8325
Echinococcus granulosus	glutamate receptor 2	0.0014	0.0171	0.0346
Echinococcus multilocularis	glutamate receptor, ionotrophic, AMPA 3	0.0014	0.0171	0.0346
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0047	0.1313	0.2655
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0297	1	1
Schistosoma mansoni	glutamate receptor kainate	0.0009	0.0012	0.0012
Leishmania major	pyruvate kinase	0.0035	0.0918	0.3286
Echinococcus multilocularis	glutamate receptor ionotropic kainate	0.0009	0.0012	0.0023
Schistosoma mansoni	cpg binding protein	0.0032	0.0809	0.0867
Plasmodium falciparum	holo-[acyl-carrier-protein] synthase, putative	0.0024	0.0525	0.336
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0047	0.1313	0.1406
Echinococcus multilocularis	nmda type glutamate receptor	0.01	0.3159	0.6389
Loa Loa (eye worm)	hypothetical protein	0.0151	0.4945	0.5292
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0047	0.1313	0.1406
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0029	0.0714	0.1444
Echinococcus multilocularis	pyruvate kinase	0.0018	0.0326	0.0659
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0297	1	1
Echinococcus granulosus	glutamate receptor ionotropic kainate 3	0.0009	0.0012	0.0023
Echinococcus multilocularis	pyruvate kinase	0.0018	0.0326	0.0659
Mycobacterium leprae	Probable fructose bisphosphate aldolase Fba	0.0145	0.4732	1
Chlamydia trachomatis	pyruvate kinase	0.0035	0.0918	1
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0058	0.1722	0.1386
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0297	1	1
Brugia malayi	Inositol-1	0.0037	0.0998	0.1058
Brugia malayi	Pyruvate kinase, M2 isozyme	0.0035	0.0918	0.0973
Mycobacterium ulcerans	phosphopantetheinyl transferase, PptII	0.0024	0.0525	0.0031
Mycobacterium leprae	possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ).	0.0034	0.0862	0.08
Leishmania major	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0998	0.3947
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0047	0.1313	0.1406
Schistosoma mansoni	pyruvate kinase	0.0035	0.0918	0.0984
Trichomonas vaginalis	glutaminase, putative	0.0278	0.9334	0.9266
Schistosoma mansoni	glutamate receptor kainate	0.0009	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.0025	0.055	0.0578
Onchocerca volvulus		0.0085	0.2631	0.257
Echinococcus multilocularis	inositol monophosphatase 1	0.0037	0.0998	0.2017
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0065	0.1963	0.2103
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.0037	0.0998	0.0087
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.001	0.0064	0.0129
Echinococcus granulosus	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0058	0.1722	0.3483
Entamoeba histolytica	myo-inositol monophosphatase, putative	0.0037	0.0998	0.0499
Echinococcus granulosus	glutamate receptor ionotropic kainate	0.0009	0.0012	0.0023
Leishmania major	pyruvate kinase	0.0035	0.0918	0.3286
Schistosoma mansoni	glutamate receptor AMPA	0.0009	0.0012	0.0012
Trypanosoma brucei	pyruvate kinase 1, putative	0.0035	0.0918	0.8325
Treponema pallidum	4'-phosphopantetheinyl transferase	0.0024	0.0525	0.0029
Echinococcus multilocularis	pyruvate kinase	0.0028	0.0662	0.1339
Mycobacterium ulcerans	glutaminase	0.0278	0.9334	1
Wolbachia endosymbiont of Brugia malayi	fructose-1,6-bisphosphatase	0.0037	0.0998	1
Echinococcus multilocularis	Glutamate receptor, ionotropic kainate 3	0.0032	0.0808	0.1634
Loa Loa (eye worm)	CXXC zinc finger family protein	0.003	0.0749	0.0791
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0998	1
Echinococcus multilocularis	NMDA receptor	0.0009	0.0012	0.0023
Echinococcus multilocularis	glutamate receptor 2	0.0009	0.0012	0.0023
Echinococcus granulosus	pyruvate kinase	0.0018	0.0326	0.0659
Brugia malayi	3-hydroxyacyl-CoA dehydrogenase type II	0.0058	0.1722	0.1835
Echinococcus granulosus	glutamate receptor ionotrophic AMPA 3	0.0014	0.0171	0.0346
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0031	0.0776	0.1569
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.001	0.0064	0.0129
Loa Loa (eye worm)	glutaminase	0.0278	0.9334	1
Mycobacterium leprae	Probable pyruvate kinase PykA	0.0035	0.0918	0.0935
Schistosoma mansoni	ATP-binding cassette transporter	0.0009	0.0012	0.0012
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0212	0.7058	0.7558
Echinococcus granulosus	inositol monophosphatase 1	0.0037	0.0998	0.2017
Echinococcus granulosus	glutamate NMDA receptor subunit	0.0009	0.0012	0.0023
Echinococcus granulosus	nmda type glutamate receptor	0.01	0.3159	0.6389
Echinococcus granulosus	glutamate receptor NMDA	0.0095	0.3	0.6067
Toxoplasma gondii	4'-phosphopantetheinyl transferase domain-containing protein	0.0024	0.0525	0.1423
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0297	1	1
Echinococcus granulosus	pyruvate kinase	0.0018	0.0326	0.0659
Schistosoma mansoni	inositol monophosphatase	0.0037	0.0998	0.1069
Onchocerca volvulus	Pyruvate kinase homolog	0.0035	0.0918	0.0231
Echinococcus multilocularis	glutamate (NMDA) receptor subunit	0.0009	0.0012	0.0023
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0047	0.1313	0.1396
Onchocerca volvulus	Pyruvate kinase homolog	0.0035	0.0918	0.0231
Leishmania major	3-oxoacyl-(acyl-carrier protein) reductase, putative	0.0058	0.1722	1
Plasmodium vivax	pyruvate kinase, putative	0.0035	0.0918	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0047	0.1313	0.2655
Giardia lamblia	Fructose-bisphosphate aldolase	0.0297	1	1
Mycobacterium ulcerans	pyruvate kinase	0.0035	0.0918	0.0477
Echinococcus multilocularis	cpg binding protein	0.0032	0.0809	0.1636
Loa Loa (eye worm)	hypothetical protein	0.0151	0.4945	0.5292
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0031	0.0776	0.0831
Echinococcus granulosus	L aminoadipate semialdehyde	0.0085	0.2631	0.532
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0058	0.1722	0.1386
Mycobacterium tuberculosis	Inositol-1-monophosphatase SuhB	0.0034	0.0862	0.0861
Echinococcus multilocularis	Glutamate receptor, ionotropic kainate 2	0.0014	0.0171	0.0346
Brugia malayi	glutaminase DH11.1	0.0278	0.9334	1
Echinococcus granulosus	pyruvate kinase	0.0018	0.0326	0.0659
Echinococcus granulosus	muscleblind protein	0.0151	0.4945	1
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0047	0.1313	0.2655
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0031	0.0776	0.3215
Schistosoma mansoni	pyruvate kinase	0.0018	0.0326	0.0349

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 0.027 uM	Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.	ChEMBL.	1534584
IC50 (binding)	= 0.027 uM	Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.	ChEMBL.	1534584
Kb (functional)	= 0.34 uM	Compound was evaluated for antagonism of depolarizations due to NMDA in a rat cortical slice preparation	ChEMBL.	1534584
Kb (functional)	= 0.34 uM	Compound was evaluated for antagonism of depolarizations due to NMDA in a rat cortical slice preparation	ChEMBL.	1534584

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL301634

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 87916