Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.1305 | 1 | 0.5 | |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.0058 | 0.0301 | 0.0301 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1305 | 1 | 1 |
Plasmodium vivax | cyclin dependent kinase 7 (cdk7), putative | 0.0019 | 0 | 0.5 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.0066 | 0.0365 | 0.0365 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0058 | 0.0301 | 1 |
Brugia malayi | cyclin-dependent kinase 9 | 0.0058 | 0.0301 | 0.0301 |
Plasmodium vivax | serine/threonine protein kinase KIN, putative | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | kinase | 0.0058 | 0.0301 | 0.0301 |
Echinococcus granulosus | CDC7 cell division cycle 7 | 0.1305 | 1 | 1 |
Echinococcus multilocularis | CDC7 cell division cycle 7 | 0.1305 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1305 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1305 | 1 | 1 |
Plasmodium falciparum | MO15-related protein kinase | 0.0019 | 0 | 0.5 |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.0066 | 0.0365 | 0.0365 |
Onchocerca volvulus | 0.1305 | 1 | 0.5 | |
Trypanosoma brucei | protein kinase, putative | 0.0019 | 0 | 0.5 |
Giardia lamblia | Kinase, CDC7 | 0.1305 | 1 | 1 |
Leishmania major | serine/threonine kinase-like protein, putative | 0.0019 | 0 | 0.5 |
Trypanosoma brucei | Mitogen-activated protein kinase 10, putative | 0.0019 | 0 | 0.5 |
Trypanosoma cruzi | Mitogen-activated protein kinase 10, putative | 0.0019 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1305 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDK9 protein kinase | 0.0058 | 0.0301 | 0.0301 |
Loa Loa (eye worm) | CDC7 protein kinase | 0.1305 | 1 | 1 |
Trypanosoma cruzi | serine/threonine protein kinase, putative | 0.0019 | 0 | 0.5 |
Trypanosoma cruzi | Mitogen-activated protein kinase 10, putative | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.1926 | 0.1926 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0058 | 0.0301 | 0.0301 |
Leishmania major | mitogen-activated protein kinase, putative,map kinase-like protein | 0.0019 | 0 | 0.5 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.0058 | 0.0301 | 0.0301 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.