Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.2594 | 0.7326 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1347 | 0.2397 | 0.2491 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0933 | 0.0763 | 0.1041 |
Echinococcus granulosus | cathepsin l1 | 0.0933 | 0.0763 | 0.1041 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3271 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3271 | 1 | 1 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.2594 | 0.7326 | 1 |
Leishmania major | cathepsin L-like protease | 0.3271 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1347 | 0.2397 | 0.3273 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1347 | 0.2397 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.3271 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.1347 | 0.2397 | 0.3273 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.3271 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3271 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.3271 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3271 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.1347 | 0.2397 | 0.3273 |
Echinococcus multilocularis | cathepsin b | 0.2594 | 0.7326 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3271 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0933 | 0.0763 | 0.1041 |
Echinococcus multilocularis | cysteine protease | 0.1347 | 0.2397 | 0.3273 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2594 | 0.7326 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1347 | 0.2397 | 0.3273 |
Onchocerca volvulus | 0.1347 | 0.2397 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1347 | 0.2397 | 0.3273 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3271 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.128 | 0.2134 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.1347 | 0.2397 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1347 | 0.2397 | 0.2397 |
Giardia lamblia | Cathepsin B precursor | 0.128 | 0.2134 | 0.5 |
Loa Loa (eye worm) | cysteine protease | 0.1347 | 0.2397 | 0.2491 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Echinococcus granulosus | cathepsin b | 0.2594 | 0.7326 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0933 | 0.0763 | 0.1041 |
Onchocerca volvulus | 0.1347 | 0.2397 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Leishmania major | cathepsin L-like protease | 0.1347 | 0.2397 | 0.0335 |
Brugia malayi | Cathepsin L-like precursor | 0.1347 | 0.2397 | 0.3273 |
Leishmania major | cathepsin L-like protease | 0.1347 | 0.2397 | 0.0335 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1347 | 0.2397 | 0.3273 |
Onchocerca volvulus | 0.1347 | 0.2397 | 1 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.128 | 0.2134 | 0.2134 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2594 | 0.7326 | 0.7326 |
Toxoplasma gondii | cathepsin CPL | 0.1347 | 0.2397 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1347 | 0.2397 | 0.3273 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1347 | 0.2397 | 0.3273 |
Onchocerca volvulus | Cathepsin F homolog | 0.1347 | 0.2397 | 1 |
Leishmania major | cathepsin L-like protease | 0.3271 | 1 | 1 |
Onchocerca volvulus | 0.1347 | 0.2397 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2594 | 0.7326 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2594 | 0.7326 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0933 | 0.0763 | 0.3182 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.225 | 0.5968 | 0.5968 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Plasmodium vivax | vivapain-2 | 0.1347 | 0.2397 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0933 | 0.0763 | 0.1041 |
Echinococcus granulosus | cathepsin b | 0.2594 | 0.7326 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1347 | 0.2397 | 0.3273 |
Leishmania major | cathepsin L-like protease | 0.1347 | 0.2397 | 0.0335 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3271 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1347 | 0.2397 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1347 | 0.2397 | 0.2491 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1347 | 0.2397 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.128 | 0.2134 | 0.2134 |
Brugia malayi | Cathepsin L-like precursor | 0.1347 | 0.2397 | 0.3273 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1347 | 0.2397 | 0.3273 |
Onchocerca volvulus | 0.1347 | 0.2397 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1347 | 0.2397 | 0.3273 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1347 | 0.2397 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1347 | 0.2397 | 0.3273 |
Leishmania major | cathepsin L-like protease | 0.1347 | 0.2397 | 0.0335 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0933 | 0.0763 | 0.3182 |
Onchocerca volvulus | 0.1347 | 0.2397 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3271 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.128 | 0.2134 | 0.8901 |
Onchocerca volvulus | Cathepsin L homolog | 0.1347 | 0.2397 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.2857 | 0.8365 | 0.8365 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.128 | 0.2134 | 0.2913 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0933 | 0.0763 | 0.1041 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2594 | 0.7326 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0933 | 0.0763 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3271 | 1 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.1347 | 0.2397 | 0.0335 |
Plasmodium vivax | vivapain-2 | 0.1347 | 0.2397 | 1 |
Loa Loa (eye worm) | fibroinase | 0.1347 | 0.2397 | 0.2491 |
Echinococcus multilocularis | cathepsin b | 0.2594 | 0.7326 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3271 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1347 | 0.2397 | 0.2491 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.128 | 0.2134 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.3271 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3271 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1347 | 0.2397 | 0.0335 |
Loa Loa (eye worm) | ctsf protein | 0.1347 | 0.2397 | 0.2491 |
Onchocerca volvulus | 0.1347 | 0.2397 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1347 | 0.2397 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1347 | 0.2397 | 0.3273 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1347 | 0.2397 | 0.3273 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1347 | 0.2397 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.128 | 0.2134 | 0.2089 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1347 | 0.2397 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1347 | 0.2397 | 0.3273 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.