Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0063 | 0.158 | 0.3857 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0023 | 0.0264 | 0.0711 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0023 | 0.0264 | 0.0643 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0183 | 0.5589 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0138 | 0.4096 | 0.5271 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0035 | 0.0663 | 0.1618 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1111 | 0.143 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0307 | 0.0307 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0264 | 0.0264 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0023 | 0.0264 | 0.0643 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0092 | 0.2546 | 0.6217 |
Brugia malayi | Transient-receptor-potential like protein | 0.0035 | 0.0663 | 0.0663 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.4096 | 0.5271 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0264 | 0.0339 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0264 | 0.0643 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0307 | 0.2247 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0597 | 0.0597 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.1707 | 0.2197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0307 | 0.0395 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0264 | 0.0643 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0183 | 0.5589 | 0.5 |
Schistosoma mansoni | transient receptor potential channel | 0.0063 | 0.158 | 0.3857 |
Onchocerca volvulus | 0.0183 | 0.5589 | 1 | |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.3381 | 0.3381 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0023 | 0.0264 | 0.0643 |
Schistosoma mansoni | gliotactin | 0.0023 | 0.0264 | 0.0643 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.3381 | 0.435 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0015 | 0.0015 |
Schistosoma mansoni | transient receptor potential channel | 0.0095 | 0.2652 | 0.6475 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0063 | 0.158 | 0.3857 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0264 | 0.0264 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0307 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0056 | 0.1366 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0138 | 0.4096 | 1 |
Trypanosoma brucei | low molecular weight protein tyrosine phosphatase, putative | 0.0056 | 0.1366 | 1 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0095 | 0.2652 | 0.6475 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.7771 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0264 | 0.0339 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0023 | 0.0264 | 0.0643 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0307 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0138 | 0.4096 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0264 | 0.0264 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0264 | 0.0643 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.3936 | 0.5066 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0095 | 0.2652 | 0.6475 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0264 | 0.0339 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0663 | 0.0853 |
Echinococcus multilocularis | neuroligin | 0.0023 | 0.0264 | 0.0643 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.0264 | 0.0339 |
Brugia malayi | hypothetical protein | 0.0148 | 0.4416 | 0.4416 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0063 | 0.158 | 0.3857 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0264 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0264 | 0.0339 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0597 | 0.1456 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0023 | 0.0264 | 0.0711 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0023 | 0.0264 | 0.0711 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.0126 | 0.3707 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0307 | 1 |
Onchocerca volvulus | 0.0148 | 0.4416 | 0.7797 | |
Echinococcus granulosus | acetylcholinesterase | 0.0138 | 0.4096 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0264 | 0.0264 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0307 | 0.2247 |
Mycobacterium ulcerans | phosphotyrosine protein phosphatase PtpA | 0.0183 | 0.5589 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0138 | 0.4096 | 1 |
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.0183 | 0.5589 | 0.7192 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.4096 | 0.5271 |
Leishmania major | hypothetical protein, conserved | 0.0056 | 0.1366 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0138 | 0.4096 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0023 | 0.0264 | 0.0643 |
Schistosoma mansoni | transient receptor potential channel | 0.0063 | 0.158 | 0.3857 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0307 | 0.2247 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0183 | 0.5589 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0023 | 0.0264 | 0.0643 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1474 | 0.1897 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0056 | 0.1366 | 1 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0183 | 0.5589 | 1 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0183 | 0.5589 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1111 | 0.143 |
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.0183 | 0.5589 | 0.5589 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.4416 | 0.5683 |
Brugia malayi | Carboxylesterase family protein | 0.0138 | 0.4096 | 0.4096 |
Schistosoma mansoni | acetylcholinesterase | 0.0023 | 0.0264 | 0.0643 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2652 | 0.3413 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.0264 | 0.0339 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0597 | 0.0768 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0557 | 0.0717 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0307 | 1 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0183 | 0.5589 | 1 |
Giardia lamblia | Low molecular weight protein-tyrosine-phosphatase | 0.0183 | 0.5589 | 0.5 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0095 | 0.2652 | 0.6475 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1111 | 0.1111 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0264 | 0.0339 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0307 | 0.2247 |
Echinococcus granulosus | neuroligin | 0.0023 | 0.0264 | 0.0643 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0056 | 0.1366 | 0.207 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0138 | 0.4096 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0264 | 0.0339 |
Brugia malayi | Carboxylesterase family protein | 0.0138 | 0.4096 | 0.4096 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0138 | 0.4096 | 1 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0183 | 0.5589 | 1 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0115 | 0.3319 | 0.8103 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.3381 | 0.435 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0092 | 0.2546 | 0.6217 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0183 | 0.5589 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0264 | 0.0339 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0063 | 0.158 | 0.3857 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0138 | 0.4096 | 0.5271 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1111 | 0.1111 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0056 | 0.1366 | 0.207 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0023 | 0.0264 | 0.0643 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0035 | 0.0663 | 0.1618 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0023 | 0.0264 | 0.0643 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.