Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0548 | 1 | 1 | |
Mycobacterium tuberculosis | 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.0209 | 0.3568 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.0209 | 0.3568 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0209 | 0.3568 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0567 | 0.0567 |
Trypanosoma brucei | adenosine kinase, putative | 0.0021 | 0 | 0.5 |
Mycobacterium ulcerans | fructokinase, PfkB | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0051 | 0.0567 | 0.1589 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0051 | 0.0567 | 0.0567 |
Entamoeba histolytica | Hypothetical protein T24C12.3, putative | 0.0021 | 0 | 0.5 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0051 | 0.0567 | 0.5 |
Trypanosoma brucei | ribokinase, putative | 0.0021 | 0 | 0.5 |
Entamoeba histolytica | tagatose-6-phosphate kinase, putative | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0051 | 0.0567 | 0.1589 |
Loa Loa (eye worm) | serotonin transporter b | 0.0051 | 0.0567 | 0.0567 |
Leishmania major | tagatose-6-phosphate kinase-like protein | 0.0021 | 0 | 0.5 |
Giardia lamblia | Ribokinase | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | adenosine kinase, putative | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0209 | 0.3568 | 1 |
Leishmania major | adenosine kinase-like protein | 0.0021 | 0 | 0.5 |
Mycobacterium tuberculosis | Adenosine kinase | 0.0021 | 0 | 0.5 |
Toxoplasma gondii | kinase, pfkB family protein | 0.0021 | 0 | 0.5 |
Leishmania major | ribokinase, putative | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.3568 | 0.3568 |
Leishmania major | adenosine kinase-like protein | 0.0021 | 0 | 0.5 |
Onchocerca volvulus | 0.0051 | 0.0567 | 0.0567 | |
Trypanosoma brucei | adenosine kinase, putative | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | adenosine kinase, putative | 0.0021 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0 | 0.5 |
Leishmania major | putative PfkB family sugar kinase | 0.0021 | 0 | 0.5 |
Leishmania major | tagatose-6-phosphate kinase-like protein | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0548 | 1 | 1 |
Trichomonas vaginalis | ribokinase, putative | 0.0021 | 0 | 0.5 |
Mycobacterium ulcerans | carbohydrate kinase CbhK | 0.0021 | 0 | 0.5 |
Entamoeba histolytica | ribokinase, putative | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | serotonin transporter | 0.0051 | 0.0567 | 0.1589 |
Trypanosoma brucei | ribokinase, putative | 0.0021 | 0 | 0.5 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0051 | 0.0567 | 0.0567 |
Trypanosoma cruzi | ribokinase, putative | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0567 | 0.0567 |
Leishmania major | adenosine kinase, putative | 0.0021 | 0 | 0.5 |
Mycobacterium leprae | Probable adenosine kinase adk | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0567 | 0.0567 |
Toxoplasma gondii | kinase, pfkB family protein | 0.0021 | 0 | 0.5 |
Entamoeba histolytica | kinase, PfkB family | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0051 | 0.0567 | 0.0567 |
Trichomonas vaginalis | ribokinase, putative | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.3568 | 0.3568 |
Mycobacterium tuberculosis | Ribokinase RbsK | 0.0021 | 0 | 0.5 |
Entamoeba histolytica | fructokinase, putative | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | adenosine kinase, putative | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | adenosine kinase, putative | 0.0021 | 0 | 0.5 |
Trichomonas vaginalis | ribokinase, putative | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | serotonin transporter | 0.0051 | 0.0567 | 0.1589 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.