Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.014 | 0.0575 | 0.0381 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0189 | 0.0978 | 0.4044 |
Trichomonas vaginalis | glycogen debranching enzyme, putative | 0.0141 | 0.059 | 0.239 |
Schistosoma mansoni | alpha glucosidase | 0.0189 | 0.0978 | 0.0762 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0133 | 0.0525 | 0.2111 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0525 | 0.0525 |
Echinococcus granulosus | fucosidase alpha L 1 tissue | 0.0822 | 0.6126 | 0.5883 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.1299 | 1 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0189 | 0.0978 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0231 | 0.1318 | 0.0773 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0133 | 0.0525 | 0.2111 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0189 | 0.0978 | 0.0978 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0133 | 0.0525 | 0.2111 |
Trichomonas vaginalis | glycogen debranching enzyme, putative | 0.0141 | 0.059 | 0.239 |
Schistosoma mansoni | alpha-l-fucosidase | 0.0822 | 0.6126 | 0.6312 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0189 | 0.0978 | 0.345 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0189 | 0.0978 | 0.4044 |
Entamoeba histolytica | glycogen debranching enzyme, putative | 0.0141 | 0.059 | 0.1442 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.0575 | 0.0381 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.1318 | 0.1318 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0133 | 0.0525 | 0.2111 |
Onchocerca volvulus | 0.0934 | 0.7031 | 1 | |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0133 | 0.0525 | 0.2111 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0189 | 0.0978 | 1 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0189 | 0.0978 | 0.4044 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0133 | 0.0525 | 0.2111 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0189 | 0.0978 | 0.4044 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0231 | 0.1318 | 0.0773 |
Schistosoma mansoni | alpha-glucosidase | 0.1243 | 0.9547 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0155 | 0.0703 | 0.5 |
Brugia malayi | Amylo-alpha-1,6-glucosidase family protein | 0.0141 | 0.059 | 0.0069 |
Brugia malayi | hypothetical protein | 0.0231 | 0.1318 | 0.0837 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0189 | 0.0978 | 0.4044 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.0575 | 0.0381 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.0822 | 0.6126 | 1 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.0822 | 0.6126 | 0.5883 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0189 | 0.0978 | 0.4044 |
Giardia lamblia | 4-alpha-glucanotransferase, amylo-alpha-1,6-glucosidase | 0.0141 | 0.059 | 0.5 |
Brugia malayi | Alpha-L-fucosidase family protein | 0.0822 | 0.6126 | 0.5912 |
Schistosoma mansoni | alpha-glucosidase | 0.1243 | 0.9547 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1299 | 1 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0133 | 0.0525 | 0.2111 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0295 | 0.1838 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0189 | 0.0978 | 0.4044 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0189 | 0.0978 | 0.4044 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0189 | 0.0978 | 0.345 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0295 | 0.1838 | 1 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0189 | 0.0978 | 0.4044 |
Trypanosoma brucei | glucosidase, putative | 0.0189 | 0.0978 | 0.345 |
Schistosoma mansoni | hypothetical protein | 0.0182 | 0.0919 | 0.0698 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.0822 | 0.6126 | 0.6126 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1299 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.059 | 0.059 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0361 | 0.2373 | 1 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0189 | 0.0978 | 0.0412 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0295 | 0.1838 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0295 | 0.1838 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0189 | 0.0978 | 0.345 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0189 | 0.0978 | 0.0412 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0361 | 0.2373 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0189 | 0.0978 | 0.0478 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.1299 | 1 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0133 | 0.0525 | 0.2111 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0189 | 0.0978 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.