Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | tyrosin kinase, putative | 0.0013 | 0.0117 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0762 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0762 | 0.0719 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.015 | 1 | 1 |
Schistosoma mansoni | eyes absent homolog | 0.0118 | 0.7696 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0762 | 0.0719 |
Loa Loa (eye worm) | plexin A | 0.0062 | 0.3663 | 0.3634 |
Schistosoma mansoni | plexin | 0.0052 | 0.2969 | 0.3858 |
Schistosoma mansoni | plexin | 0.0031 | 0.1385 | 0.18 |
Brugia malayi | hypothetical protein | 0.0118 | 0.7696 | 0.7506 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0762 | 0.0719 |
Onchocerca volvulus | 0.0052 | 0.2969 | 0.2585 | |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0762 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0213 | 0.0168 |
Echinococcus granulosus | roundabout 2 | 0.0014 | 0.0213 | 0.0583 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0013 | 0.0117 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.7696 | 0.7686 |
Echinococcus granulosus | semaphorin 5B | 0.0022 | 0.0762 | 0.2081 |
Echinococcus multilocularis | semaphorin 5B | 0.0022 | 0.0762 | 0.2081 |
Loa Loa (eye worm) | sema domain-containing protein | 0.0022 | 0.0762 | 0.0719 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0762 | 0.099 |
Onchocerca volvulus | 0.0134 | 0.8887 | 0.9517 | |
Brugia malayi | Plexin repeat family protein | 0.0052 | 0.2969 | 0.2389 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.014 | 0.9299 | 1 |
Echinococcus multilocularis | plexin a4 | 0.0062 | 0.3663 | 1 |
Loa Loa (eye worm) | sema domain-containing protein | 0.0022 | 0.0762 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0213 | 0.0168 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.1385 | 0.1345 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0012 | 0.0046 | 0.0126 |
Echinococcus granulosus | plexin a4 | 0.0062 | 0.3663 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0762 | 0.099 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0762 | 0.0719 |
Echinococcus multilocularis | hypothetical protein | 0.0022 | 0.0762 | 0.2081 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.1385 | 0.18 |
Echinococcus granulosus | semaphorin 1A | 0.0022 | 0.0762 | 0.2081 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2969 | 0.2937 |
Echinococcus multilocularis | roundabout 2 | 0.0014 | 0.0213 | 0.0583 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.7696 | 0.7686 |
Schistosoma mansoni | cell adhesion molecule | 0.0012 | 0.0046 | 0.006 |
Schistosoma mansoni | semaphorin 5-related | 0.0022 | 0.0762 | 0.099 |
Brugia malayi | plexin A | 0.0062 | 0.3663 | 0.314 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.