Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | adenosine deaminase, putative | 0.0258 | 0.8056 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.0084 | 0 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0258 | 0.8056 | 0.5 |
Echinococcus granulosus | adenosine deaminase | 0.0258 | 0.8056 | 0.8056 |
Brugia malayi | Adenosine/AMP deaminase family protein | 0.0258 | 0.8056 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.4164 | 0.5169 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0258 | 0.8056 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.4164 | 0.5169 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0258 | 0.8056 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.03 | 1 | 1 |
Schistosoma mansoni | P2X receptor subunit | 0.03 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0258 | 0.8056 | 1 |
Plasmodium falciparum | adenosine deaminase | 0.0258 | 0.8056 | 1 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0258 | 0.8056 | 1 |
Trypanosoma brucei | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Brugia malayi | Cytochrome P450 family protein | 0.0091 | 0.0312 | 0.0388 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.03 | 1 | 1 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.03 | 1 | 1 |
Plasmodium vivax | adenosine deaminase, putative | 0.0258 | 0.8056 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0258 | 0.8056 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.4164 | 0.5169 |
Mycobacterium ulcerans | adenosine deaminase | 0.0258 | 0.8056 | 0.5 |
Schistosoma mansoni | P2X receptor subunit | 0.03 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.03 | 1 | 1 |
Echinococcus multilocularis | adenosine deaminase | 0.0258 | 0.8056 | 0.8056 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0258 | 0.8056 | 1 |
Schistosoma mansoni | adenosine deaminase | 0.0258 | 0.8056 | 0.8056 |
Treponema pallidum | adenosine deaminase | 0.0258 | 0.8056 | 0.5 |
Leishmania major | adenine aminohydrolase | 0.0258 | 0.8056 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Schistosoma mansoni | P2X receptor subunit | 0.0149 | 0.2997 | 0.2997 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.4164 | 0.5169 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.0084 | 0 | 0.5 |
Schistosoma mansoni | P2X receptor subunit | 0.0149 | 0.2997 | 0.2997 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.03 | 1 | 1 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0258 | 0.8056 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0091 | 0.0312 | 0.0388 |
Trypanosoma brucei | adenosine monophosphate deaminase, putative | 0.0084 | 0 | 0.5 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0258 | 0.8056 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0258 | 0.8056 | 0.8056 |
Trypanosoma cruzi | AMP deaminase 2, putative | 0.0084 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.