TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 363.433 | Formula: C20H17N3O2S
H donors: 1 H acceptors: 2 LogP: 4.49 Rotable bonds: 3
Rule of 5 violations (Lipinski): 1
SMILES: Oc1c(C=Nc2c(C)n(n(c2=O)c2ccccc2)C)sc2c1cccc2
InChi: 1S/C20H17N3O2S/c1-13-18(20(25)23(22(13)2)14-8-4-3-5-9-14)21-12-17-19(24)15-10-6-7-11-16(15)26-17/h3-12,24H,1-2H3
InChiKey: ZASAYZWVTFXHHU-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	hypothetical protein	0.0678	0.2576	1
Echinococcus granulosus	sex peptide receptor	0.0056	0.0183	0.0183
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.0183	0.0698
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0018	0.0037	0.0444
Onchocerca volvulus		0.0014	0.002	0.0009
Brugia malayi	Melatonin receptor type 1A	0.0056	0.0183	0.0645
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0146	0.0528	0.2038
Onchocerca volvulus		0.0056	0.0183	0.0645
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Schistosoma mansoni	neuropeptide receptor	0.0056	0.0183	0.0698
Schistosoma mansoni	hypothetical protein	0.0112	0.0397	0.1531
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0056	0.0183	0.0183
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0146	0.0528	1
Brugia malayi	PAN domain containing protein	0.0014	0.002	0.0009
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.0146	0.0528	0.2038
Schistosoma mansoni	amine GPCR	0.0056	0.0183	0.0698
Brugia malayi	Chymotrypsin-like protease CTRL-1 precursor	0.0059	0.0193	0.0684
Brugia malayi	PAN domain containing protein	0.0014	0.002	0.0009
Loa Loa (eye worm)	hypothetical protein	0.0014	0.002	0.0078
Brugia malayi	hypothetical protein	0.0056	0.0183	0.0645
Mycobacterium tuberculosis	Probable protease II PtrBa [first part] (oligopeptidase B)	0.0113	0.0404	1
Brugia malayi	hypothetical protein	0.0056	0.0183	0.0645
Echinococcus multilocularis	g protein coupled receptor	0.0056	0.0183	0.0183
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0018	0.0037	0.0037
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0056	0.0183	0.0183
Loa Loa (eye worm)	PAN domain-containing protein	0.0014	0.002	0.0078
Brugia malayi	hypothetical protein	0.0059	0.0193	0.0684
Onchocerca volvulus		0.0056	0.0183	0.0645
Plasmodium vivax	hypothetical protein, conserved	0.0013	0.0018	0.0374
Brugia malayi	G protein-coupled receptor	0.0056	0.0183	0.0645
Echinococcus granulosus	g protein coupled receptor	0.0056	0.0183	0.0183
Echinococcus multilocularis	enteropeptidase	0.0059	0.0193	0.0193
Echinococcus multilocularis	g-protein coupled receptor	0.0056	0.0183	0.0183
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0056	0.0183	0.0183
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Echinococcus granulosus	ATP dependent DNA helicase Q5	0.0019	0.0041	0.0041
Echinococcus granulosus	biogenic amine 5HT receptor	0.0056	0.0183	0.0183
Echinococcus granulosus	prolyl endopeptidase	0.0127	0.0455	0.0455
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Toxoplasma gondii	hypothetical protein	0.0014	0.002	0.003
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0056	0.0183	0.0183
Trichomonas vaginalis	DNA helicase recq1, putative	0.0019	0.0041	0.1732
Toxoplasma gondii	ATP-dependent DNA helicase, RecQ family protein	0.0019	0.0041	0.0067
Onchocerca volvulus	Prolyl endopeptidase homolog	0.0127	0.0455	0.1708
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0193	0.0749
Brugia malayi	prolyl oligopeptidase family protein	0.0127	0.0455	0.1708
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0018	0.0037	1
Brugia malayi	Trypsin family protein	0.0059	0.0193	0.0684
Trichomonas vaginalis	DNA helicase recq, putative	0.0019	0.0041	0.1732
Onchocerca volvulus		0.0014	0.002	0.0009
Schistosoma mansoni	hypothetical protein	0.0059	0.0193	0.0737
Schistosoma mansoni	neuropeptide F-like receptor	0.0056	0.0183	0.0698
Schistosoma mansoni	cercarial elastase (S01 family)	0.0059	0.0193	0.0737
Echinococcus multilocularis	neuropeptide receptor A26	0.0056	0.0183	0.0183
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Loa Loa (eye worm)	PAN domain-containing protein	0.0014	0.002	0.0078
Toxoplasma gondii	microneme protein MIC17B	0.0014	0.002	0.003
Leishmania major	oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein	0.005	0.0161	0.3271
Toxoplasma gondii	acylaminoacyl-peptidase, putative	0.0013	0.0018	0.0026
Toxoplasma gondii	cathepsin B	0.0048	0.0152	0.0263
Brugia malayi	GnHR receptor homolog	0.0056	0.0183	0.0645
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0056	0.0183	0.0183
Brugia malayi	neuropeptide F receptor	0.0056	0.0183	0.0645
Trypanosoma brucei	oligopeptidase b	0.005	0.0161	0.3271
Brugia malayi	Trypsin family protein	0.0678	0.2576	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0041	0.0159
Brugia malayi	hypothetical protein	0.0056	0.0183	0.0645
Echinococcus granulosus	7tm_1 domain containing protein	0.0056	0.0183	0.0183
Echinococcus granulosus	cpg binding protein	0.003	0.0081	0.0081
Onchocerca volvulus		0.0056	0.0183	0.0645
Loa Loa (eye worm)	prolyl oligopeptidase	0.0013	0.0018	0.0069
Echinococcus granulosus	G protein coupled receptor 139	0.0056	0.0183	0.0183
Echinococcus multilocularis	tissue type plasminogen activator	0.0112	0.0397	0.0397
Echinococcus granulosus	neuropeptide receptor	0.0056	0.0183	0.0183
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Schistosoma mansoni	cpg binding protein	0.003	0.0081	0.0301
Brugia malayi	hypothetical protein	0.0056	0.0183	0.0645
Onchocerca volvulus		0.0056	0.0183	0.0645
Schistosoma mansoni	hypothetical protein	0.0059	0.0193	0.0737
Brugia malayi	ATP-dependent DNA helicase, RecQ family protein	0.0019	0.0041	0.0091
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0018	0.0037	0.0625
Onchocerca volvulus		0.0056	0.0183	0.0645
Toxoplasma gondii	microneme protein MIC17C	0.0014	0.002	0.003
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0056	0.0183	0.0698
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.0183	0.0698
Echinococcus multilocularis	neuropeptide Y receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	cpg binding protein	0.0028	0.0074	0.0277
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.0018	0.0037	0.8998
Entamoeba histolytica	prolyl oligopeptidase family protein	0.0013	0.0018	0.3884
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0018	0.0037	0.0145
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0059	0.0195	0.0747
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Schistosoma mansoni	opsin-like receptor	0.0056	0.0183	0.0698
Echinococcus multilocularis	dnaJ subfamily B	0.0399	0.1502	0.1502
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Schistosoma mansoni	hypothetical protein	0.0056	0.0183	0.0698
Toxoplasma gondii	PAN domain-containing protein	0.0014	0.002	0.003
Onchocerca volvulus		0.0056	0.0183	0.0645
Loa Loa (eye worm)	melatonin receptor type 1A	0.0056	0.0183	0.071
Echinococcus multilocularis	cpg binding protein	0.003	0.0081	0.0081
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Giardia lamblia	Sgs1 DNA helicase, putative	0.0019	0.0041	0.1732
Echinococcus granulosus	Peptidase S1 S6 chymotrypsin Hap	0.0059	0.0193	0.0193
Schistosoma mansoni	cercarial elastase (S01 family)	0.0059	0.0193	0.0737
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0146	0.0528	0.2038
Giardia lamblia	Cathepsin B precursor	0.0048	0.0152	1
Loa Loa (eye worm)	RecQ helicase	0.0019	0.0041	0.0159
Loa Loa (eye worm)	PAN domain-containing protein	0.0014	0.002	0.0078
Brugia malayi	hypothetical protein	0.0056	0.0183	0.0645
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0053	0.0171	0.0297
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Echinococcus granulosus	bloom syndrome protein	0.0019	0.0041	0.0041
Schistosoma mansoni	biogenic amine receptor	0.0056	0.0183	0.0698
Echinococcus multilocularis	ATP dependent DNA helicase Q5	0.0019	0.0041	0.0041
Trypanosoma cruzi	oligopeptidase b	0.005	0.0161	0.2987
Schistosoma mansoni	acylaminoacyl-peptidase (S09 family)	0.0013	0.0018	0.0057
Onchocerca volvulus		0.0014	0.002	0.0009
Echinococcus multilocularis	orexin receptor type 2	0.0056	0.0183	0.0183
Brugia malayi	CXXC zinc finger family protein	0.0028	0.0074	0.0221
Toxoplasma gondii	microneme protein MIC4	0.0014	0.002	0.003
Schistosoma mansoni	growth hormone secretagogue receptor	0.0056	0.0183	0.0698
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0018	0.0037	0.0511
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0056	0.0183	0.0645
Echinococcus granulosus	somatostatin receptor	0.0056	0.0183	0.0183
Echinococcus granulosus	neuropeptide receptor A26	0.0056	0.0183	0.0183
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0056	0.0183	0.0183
Brugia malayi	PAN domain containing protein	0.0014	0.002	0.0009
Trypanosoma brucei	ATP-dependent DEAD/H DNA helicase recQ, putative	0.0019	0.0041	0.0531
Schistosoma mansoni	cercarial elastase (S01 family)	0.0059	0.0193	0.0737
Onchocerca volvulus		0.0059	0.0193	0.0684
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0028	0.0074	0.0289
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0059	0.0193	0.0737
Trichomonas vaginalis	ap endonuclease, putative	0.0018	0.0037	0.1448
Echinococcus multilocularis	subfamily S1A unassigned peptidase (S01 family)	0.0059	0.0193	0.0193
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Brugia malayi	hypothetical protein	0.0056	0.0183	0.0645
Toxoplasma gondii	PAN domain-containing protein	0.0014	0.002	0.003
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0018	0.0037	0.0037
Echinococcus multilocularis	neuropeptide receptor	0.0056	0.0183	0.0183
Echinococcus granulosus	neuropeptide FF receptor 2	0.0056	0.0183	0.0183
Mycobacterium ulcerans	hypothetical protein	0.0059	0.0193	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.0183	0.0698
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Echinococcus multilocularis	Mastin	0.0059	0.0193	0.0193
Onchocerca volvulus		0.0056	0.0183	0.0645
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0059	0.0193	0.0737
Toxoplasma gondii	kringle domain-containing protein	0.0112	0.0397	0.0698
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0056	0.0183	0.0183
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0056	0.0183	0.0183
Leishmania major	prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative	0.0127	0.0455	1
Onchocerca volvulus		0.0056	0.0183	0.0645
Toxoplasma gondii	PAN domain-containing protein	0.0014	0.002	0.003
Trypanosoma cruzi	oligopeptidase b	0.005	0.0161	0.2987
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Schistosoma mansoni	neuropeptide f receptor 76f	0.0056	0.0183	0.0698
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0018	0.0037	0.0444
Echinococcus multilocularis	dro:myosuppressin receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	cercarial elastase (S01 family)	0.0059	0.0193	0.0737
Mycobacterium leprae	PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B)	0.005	0.0161	0.5
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Onchocerca volvulus		0.0059	0.0193	0.0684
Schistosoma mansoni	cercarial elastase (S01 family)	0.0059	0.0193	0.0737
Brugia malayi	PAN domain containing protein	0.0014	0.002	0.0009
Schistosoma mansoni	cercarial elastase (S01 family)	0.0059	0.0193	0.0737
Schistosoma mansoni	subfamily S9B unassigned peptidase (S09 family)	0.0013	0.0018	0.0057
Brugia malayi	ORL1-like opioid receptor	0.0056	0.0183	0.0645
Echinococcus granulosus	acylamino acid releasing enzyme	0.0013	0.0018	0.0018
Onchocerca volvulus		0.0056	0.0183	0.0645
Echinococcus granulosus	tm gpcr rhodopsin	0.0056	0.0183	0.0183
Plasmodium falciparum	cysteine repeat modular protein 1	0.0112	0.0397	1
Brugia malayi	Bloom's syndrome protein homolog	0.0019	0.0041	0.0091
Onchocerca volvulus		0.0056	0.0183	0.0645
Loa Loa (eye worm)	hypothetical protein	0.0014	0.002	0.0078
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Echinococcus granulosus	dipeptidyl aminopeptidaseprotein	0.0013	0.0018	0.0018
Brugia malayi	hypothetical protein	0.0056	0.0183	0.0645
Trypanosoma brucei	serine peptidase, clan SC, family S9A-like protein	0.005	0.0161	0.3271
Brugia malayi	G-protein coupled receptor	0.0056	0.0183	0.0645
Echinococcus granulosus	transmembrane protease serine 3	0.0059	0.0193	0.0193
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Brugia malayi	Serotonin receptor	0.0056	0.0183	0.0645
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Giardia lamblia	Cathepsin B precursor	0.0048	0.0152	1
Echinococcus multilocularis	Dipeptidyl peptidase 9	0.0013	0.0018	0.0018
Loa Loa (eye worm)	angiotensin-converting enzyme family protein	0.0606	0.2299	0.8924
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0059	0.0193	0.0737
Entamoeba histolytica	recQ family DNA helicase	0.001	0.0005	0.0381
Echinococcus granulosus	cathepsin b	0.0146	0.0528	0.0528
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Echinococcus multilocularis	somatostatin receptor	0.0056	0.0183	0.0183
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0056	0.0183	0.0183
Toxoplasma gondii	ATP-dependent DNA helicase, RecQ family protein	0.001	0.0005	0.0003
Echinococcus granulosus	neuropeptides capa receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	cercarial elastase (S01 family)	0.0059	0.0193	0.0737
Brugia malayi	G protein-coupled receptor F59B2.13	0.0056	0.0183	0.0645
Brugia malayi	Trypsin family protein	0.0059	0.0193	0.0684
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Onchocerca volvulus		0.0014	0.002	0.0009
Brugia malayi	PAN domain containing protein	0.0014	0.002	0.0009
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Loa Loa (eye worm)	hypothetical protein	0.0014	0.002	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0193	0.0749
Echinococcus granulosus	7TM GPCR rhodopsin	0.0056	0.0183	0.0183
Onchocerca volvulus		0.0056	0.0183	0.0645
Brugia malayi	exodeoxyribonuclease III family protein	0.0018	0.0037	0.0076
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0056	0.0183	0.0183
Loa Loa (eye worm)	TYRA-2 protein	0.0056	0.0183	0.071
Echinococcus granulosus	cathepsin b	0.0146	0.0528	0.0528
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0056	0.0183	0.0698
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Echinococcus multilocularis	serotonin receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	cercarial elastase (S01 family)	0.0059	0.0193	0.0737
Echinococcus multilocularis	Peptidase S1 S6, chymotrypsin Hap	0.0059	0.0193	0.0193
Echinococcus multilocularis	allatostatin A receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0056	0.0183	0.0698
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Loa Loa (eye worm)	G-protein coupled receptor	0.0056	0.0183	0.071
Schistosoma mansoni	cercarial elastase (S01 family)	0.0059	0.0193	0.0737
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0193	0.0749
Trypanosoma cruzi	hypothetical protein, conserved	0.0013	0.0018	0.0254
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Schistosoma mansoni	DNA helicase recq1	0.0019	0.0041	0.0147
Toxoplasma gondii	hypothetical protein	0.0014	0.002	0.003
Plasmodium vivax	cysteine repeat modular protein 1, putative	0.0112	0.0397	1
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.0059	0.0193	0.0737
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Echinococcus granulosus	Mastin	0.0059	0.0193	0.0193
Schistosoma mansoni	hypothetical protein	0.0399	0.1502	0.5825
Plasmodium falciparum	ADP-dependent DNA helicase RecQ	0.0019	0.0041	0.0612
Loa Loa (eye worm)	hypothetical protein	0.001	0.0005	0.0018
Onchocerca volvulus		0.0619	0.235	0.9116
Onchocerca volvulus		0.0014	0.002	0.0009
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0056	0.0183	0.0698
Schistosoma mansoni	prolyl oligopeptidase (S09 family)	0.0127	0.0455	0.1756
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Echinococcus granulosus	Dipeptidyl peptidase 9	0.0013	0.0018	0.0018
Schistosoma mansoni	ap endonuclease	0.0018	0.0037	0.0133
Onchocerca volvulus		0.0112	0.0397	0.1482
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0059	0.0193	0.0737
Brugia malayi	Trypsin-like protease protein 5	0.0059	0.0193	0.0684
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Schistosoma mansoni	hypothetical protein	0.0056	0.0183	0.0698
Onchocerca volvulus		0.0059	0.0193	0.0684
Echinococcus multilocularis	neuropeptides capa receptor	0.0056	0.0183	0.0183
Plasmodium vivax	ADP-dependent DNA helicase RecQ, putative	0.001	0.0005	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Echinococcus granulosus	hypothetical protein	0.0056	0.0183	0.0183
Echinococcus multilocularis	transmembrane protease serine 3	0.0059	0.0193	0.0193
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0048	0.0152	0.2814
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0146	0.0528	0.2038
Trypanosoma cruzi	serine peptidase, Clan SC, Family S9B	0.0013	0.0018	0.0254
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0018	0.0037	0.5
Onchocerca volvulus		0.0678	0.2576	1
Loa Loa (eye worm)	PAN domain-containing protein	0.0014	0.002	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Brugia malayi	ATP-dependent DNA helicase, RecQ family protein	0.0019	0.0041	0.0091
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0056	0.0183	0.0645
Schistosoma mansoni	prolyl oligopeptidase (S09 family)	0.0127	0.0455	0.1756
Echinococcus granulosus	tissue type plasminogen activator	0.0112	0.0397	0.0397
Brugia malayi	Trypsin family protein	0.0059	0.0193	0.0684
Onchocerca volvulus		0.0014	0.002	0.0009
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0056	0.0183	0.0698
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0056	0.0183	0.0698
Onchocerca volvulus		0.0056	0.0183	0.0645
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0056	0.0183	0.071
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0056	0.0183	0.0183
Trypanosoma cruzi	dipeptidyl-peptidase 8-like serine peptidase	0.0013	0.0018	0.0254
Onchocerca volvulus		0.0014	0.002	0.0009
Schistosoma mansoni	biogenic amine receptor	0.0056	0.0183	0.0698
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0056	0.0183	0.0183
Entamoeba histolytica	prolyl oligopeptidase family protein	0.0013	0.0018	0.3884
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0056	0.0183	0.0698
Toxoplasma gondii	1,3(4)-beta-glucanase	0.0014	0.002	0.003
Onchocerca volvulus		0.0056	0.0183	0.0645
Loa Loa (eye worm)	hypothetical protein	0.0112	0.0397	0.1541
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0018	0.0069
Echinococcus multilocularis	dipeptidyl aminopeptidaseprotein	0.0013	0.0018	0.0018
Echinococcus granulosus	g protein coupled receptor	0.0056	0.0183	0.0183
Brugia malayi	hypothetical protein	0.0056	0.0183	0.0645
Echinococcus granulosus	enteropeptidase	0.0059	0.0193	0.0193
Echinococcus granulosus	serotonin receptor	0.0056	0.0183	0.0183
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Leishmania major	oligopeptidase b	0.005	0.0161	0.3271
Onchocerca volvulus		0.0059	0.0193	0.0684
Onchocerca volvulus		0.0014	0.002	0.0009
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0056	0.0183	0.0698
Echinococcus granulosus	g-protein coupled receptor	0.0056	0.0183	0.0183
Onchocerca volvulus		0.0014	0.002	0.0009
Toxoplasma gondii	exonuclease III APE	0.0018	0.0037	0.006
Brugia malayi	PAN domain containing protein	0.0014	0.002	0.0009
Toxoplasma gondii	hypothetical protein	0.0013	0.0018	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0014	0.002	0.0078
Schistosoma mansoni	prolyl oligopeptidase (S09 family)	0.0013	0.0018	0.0057
Brugia malayi	AKH receptor	0.0056	0.0183	0.0645
Trypanosoma brucei	prolyl oligopeptidase, putative	0.005	0.0161	0.3271
Entamoeba histolytica	recQ family helicase, putative	0.0019	0.0041	1
Schistosoma mansoni	amine GPCR	0.0056	0.0183	0.0698
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0056	0.0183	0.0698
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0056	0.0183	0.071
Brugia malayi	Dopamine receptor protein 2	0.0056	0.0183	0.0645
Brugia malayi	PAN domain containing protein	0.0014	0.002	0.0009
Schistosoma mansoni	neuropeptide receptor	0.0056	0.0183	0.0698
Echinococcus granulosus	neuropeptide s receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	adenoreceptor	0.0056	0.0183	0.0698
Echinococcus multilocularis	neuropeptide Y receptor	0.0056	0.0183	0.0183
Echinococcus multilocularis	neuropeptide s receptor	0.0056	0.0183	0.0183
Echinococcus multilocularis	cathepsin b	0.0146	0.0528	0.0528
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0056	0.0183	0.0698
Onchocerca volvulus		0.0056	0.0183	0.0645
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0056	0.0183	0.0645
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0018	0.0037	0.0866
Schistosoma mansoni	amine GPCR	0.0056	0.0183	0.0698
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0056	0.0183	0.0645
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0056	0.0183	0.0645
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0056	0.0183	0.0183
Trichomonas vaginalis	ap endonuclease, putative	0.0018	0.0037	0.1448
Loa Loa (eye worm)	hypothetical protein	0.0014	0.002	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0127	0.0455	0.1766
Loa Loa (eye worm)	hypothetical protein	0.001	0.0005	0.0018
Trypanosoma cruzi	hypothetical protein, conserved	0.0013	0.0018	0.0254
Echinococcus granulosus	neuropeptides capa receptor	0.0056	0.0183	0.0183
Brugia malayi	RE15519p	0.0056	0.0183	0.0645
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0056	0.0183	0.0698
Onchocerca volvulus		0.0014	0.002	0.0009
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0056	0.0183	0.0183
Mycobacterium tuberculosis	Probable peptidase	0.005	0.0161	0.3372
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Plasmodium falciparum	ATP-dependent DNA helicase Q1	0.0019	0.0041	0.0612
Echinococcus multilocularis	fmrfamide receptor	0.0056	0.0183	0.0183
Toxoplasma gondii	PAN domain-containing protein	0.0014	0.002	0.003
Trypanosoma cruzi	ATP-dependent DEAD/H DNA helicase recQ, putative	0.0019	0.0041	0.0697
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0056	0.0183	0.0698
Schistosoma mansoni	neuropeptide receptor	0.0056	0.0183	0.0698
Loa Loa (eye worm)	TK/ROR protein kinase	0.0112	0.0397	0.1541
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.0183	0.0698
Toxoplasma gondii	PAN domain-containing protein	0.0014	0.002	0.003
Schistosoma mansoni	hypothetical protein	0.0056	0.0183	0.0698
Brugia malayi	PAN domain containing protein	0.0014	0.002	0.0009
Toxoplasma gondii	microneme protein, putative	0.0014	0.002	0.003
Echinococcus granulosus	neuropeptide Y receptor	0.0056	0.0183	0.0183
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0056	0.0183	0.071
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0056	0.0183	0.071
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0056	0.0183	0.0183
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Echinococcus multilocularis	G protein coupled receptor 139	0.0056	0.0183	0.0183
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0056	0.0183	0.0183
Schistosoma mansoni	opsin-like receptor	0.0056	0.0183	0.0698
Onchocerca volvulus		0.0056	0.0183	0.0645
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0018	0.0037	0.1448
Onchocerca volvulus		0.0056	0.0183	0.0645
Giardia lamblia	Cathepsin B precursor	0.0048	0.0152	1
Loa Loa (eye worm)	ATP-dependent DNA helicase	0.0019	0.0041	0.0159
Entamoeba histolytica	dipeptidyl-peptidase, putative	0.0013	0.0018	0.3884
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0048	0.0152	0.3064
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Onchocerca volvulus		0.0028	0.0074	0.0221
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0193	0.0749
Brugia malayi	hypothetical protein	0.0056	0.0183	0.0645
Trypanosoma cruzi	serine peptidase, clan SC, family S9A-like protein, putative	0.005	0.0161	0.2987
Trypanosoma cruzi	oligopeptidase B-like protein, putative	0.005	0.0161	0.2987
Toxoplasma gondii	ATP-dependent DNA helicase, RecQ family protein	0.0019	0.0041	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Trypanosoma cruzi	hypothetical protein, conserved	0.0112	0.0397	0.7505
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Schistosoma mansoni	amine GPCR	0.0056	0.0183	0.0698
Echinococcus multilocularis	fmrfamide receptor	0.0056	0.0183	0.0183
Echinococcus multilocularis	glycoprotein Antigen 5	0.0059	0.0193	0.0193
Brugia malayi	Angiotensin-converting enzyme family protein	0.0606	0.2299	0.8916
Loa Loa (eye worm)	hypothetical protein	0.0014	0.002	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Echinococcus multilocularis	cathepsin b	0.0146	0.0528	0.0528
Brugia malayi	putative neuropeptide receptor NPR1	0.0056	0.0183	0.0645
Brugia malayi	Dopamine receptor protein 1	0.0056	0.0183	0.0645
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0056	0.0183	0.0698
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0056	0.0183	0.0645
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Loa Loa (eye worm)	neuropeptide F receptor	0.0056	0.0183	0.071
Echinococcus multilocularis	ATP dependent DNA helicase Q1	0.0019	0.0041	0.0041
Entamoeba histolytica	prolyl oligopeptidase family protein	0.0013	0.0018	0.3884
Schistosoma mansoni	ap endonuclease	0.0018	0.0037	0.0133
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Schistosoma mansoni	myosin xvIII	0.0056	0.0183	0.0698
Toxoplasma gondii	1,3-beta-glucan synthase component protein	0.1475	0.5644	1
Brugia malayi	larval opioid receptor	0.0056	0.0183	0.0645
Echinococcus multilocularis	acylamino acid releasing enzyme	0.0013	0.0018	0.0018
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.2606	1	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Brugia malayi	sulfakinin receptor protein	0.0056	0.0183	0.0645
Entamoeba histolytica	dipeptidyl-peptidase, putative	0.0013	0.0018	0.3884
Echinococcus multilocularis	prolyl endopeptidase	0.0127	0.0455	0.0455
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0018	0.0069
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0528	0.2048
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0193	0.0749
Echinococcus granulosus	glycoprotein Antigen 5	0.0059	0.0193	0.0193
Brugia malayi	Protein kinase domain containing protein	0.0112	0.0397	0.1482
Echinococcus granulosus	orexin receptor type 2	0.0056	0.0183	0.0183
Onchocerca volvulus		0.0059	0.0193	0.0684
Brugia malayi	Kringle domain containing protein	0.0112	0.0397	0.1482
Schistosoma mansoni	biogenic amine receptor	0.0056	0.0183	0.0698
Onchocerca volvulus		0.0056	0.0183	0.0645
Loa Loa (eye worm)	prolyl oligopeptidase	0.0013	0.0018	0.0069
Schistosoma mansoni	cercarial elastase (S01 family)	0.0059	0.0193	0.0737
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0056	0.0183	0.0698
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.0183	0.0698
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0056	0.0183	0.0645
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0056	0.0183	0.071
Schistosoma mansoni	amine GPCR	0.0056	0.0183	0.0698
Brugia malayi	putative neuropeptide receptor	0.0056	0.0183	0.0645
Echinococcus granulosus	ATP dependent DNA helicase Q1	0.0019	0.0041	0.0041
Echinococcus granulosus	neuropeptide Y receptor	0.0056	0.0183	0.0183
Brugia malayi	PAN domain containing protein	0.0014	0.002	0.0009
Toxoplasma gondii	dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein	0.0013	0.0018	0.0026
Toxoplasma gondii	PAN domain-containing protein	0.0014	0.002	0.003
Echinococcus granulosus	biogenic amine 5HT receptor	0.0056	0.0183	0.0183
Toxoplasma gondii	prolyl endopeptidase	0.0127	0.0455	0.0801
Echinococcus granulosus	dnaJ subfamily B	0.0399	0.1502	0.1502
Toxoplasma gondii	subtilisin SUB12	0.0014	0.002	0.003
Echinococcus granulosus	g protein coupled receptor	0.0056	0.0183	0.0183
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Loa Loa (eye worm)	G-protein coupled receptor	0.0056	0.0183	0.071
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0018	0.0037	0.0625
Mycobacterium tuberculosis	Probable protease II PtrBb [second part] (oligopeptidase B)	0.005	0.0161	0.3372
Schistosoma mansoni	opsin-like receptor	0.0056	0.0183	0.0698
Brugia malayi	neuropeptide F receptor	0.0056	0.0183	0.0645
Loa Loa (eye worm)	neuropeptide F receptor	0.0056	0.0183	0.071
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Echinococcus multilocularis	sex peptide receptor	0.0056	0.0183	0.0183
Echinococcus granulosus	subfamily S1A unassigned peptidase S01 family	0.0059	0.0193	0.0193
Echinococcus granulosus	fmrfamide receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	histamine h1 receptor	0.0056	0.0183	0.0698
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Trichomonas vaginalis	DNA helicase recq, putative	0.0019	0.0041	0.1732
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0678	0.2576	1
Echinococcus multilocularis	g protein coupled receptor	0.0056	0.0183	0.0183
Brugia malayi	follicle stimulating hormone receptor	0.0056	0.0183	0.0645
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0056	0.0183	0.0645
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Echinococcus multilocularis	serotonin receptor	0.0056	0.0183	0.0183
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0056	0.0183	0.0183
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0059	0.0193	0.0737
Schistosoma mansoni	cpg binding protein	0.003	0.0081	0.0301
Echinococcus granulosus	allatostatin A receptor	0.0056	0.0183	0.0183
Brugia malayi	hypothetical protein	0.0056	0.0183	0.0645
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.0183	0.0698
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0678	0.2576	1
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0056	0.0183	0.0183
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Loa Loa (eye worm)	hypothetical protein	0.0014	0.002	0.0078
Brugia malayi	Serotonin receptor	0.0056	0.0183	0.0645
Leishmania major	ATP-dependent DEAD/H DNA helicase recQ, putative	0.0019	0.0041	0.0531
Trypanosoma brucei	prolyl endopeptidase	0.0127	0.0455	1
Echinococcus granulosus	neuropeptide receptor	0.0056	0.0183	0.0183
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0056	0.0183	0.0183
Schistosoma mansoni	cercarial elastase (S01 family)	0.0059	0.0193	0.0737
Echinococcus multilocularis	bloom syndrome protein	0.0019	0.0041	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0678	0.2576	1
Brugia malayi	G-protein coupled receptor	0.0056	0.0183	0.0645
Mycobacterium ulcerans	protease II (oligopeptidase B), PtrB	0.005	0.0161	0.7938
Loa Loa (eye worm)	trypsin family protein	0.0059	0.0193	0.0749
Schistosoma mansoni	dipeptidyl-peptidase 9 (S09 family)	0.0013	0.0018	0.0057
Schistosoma mansoni	neuropeptide F-like receptor	0.0056	0.0183	0.0698
Echinococcus multilocularis	g protein coupled receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0048	0.0152	0.0578
Leishmania major	hypothetical protein, conserved	0.0112	0.0397	0.8678
Loa Loa (eye worm)	cathepsin B	0.0048	0.0152	0.0589
Onchocerca volvulus		0.0014	0.002	0.0009
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Schistosoma mansoni	DNA helicase recq5	0.0019	0.0041	0.0147
Echinococcus granulosus	tm gpcr rhodopsin	0.0056	0.0183	0.0183
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.0048	0.0152	0.3064
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0056	0.0183	0.0183
Echinococcus multilocularis	neuropeptide receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	blooms syndrome DNA helicase	0.001	0.0005	0.0006
Schistosoma mansoni	hypothetical protein	0.0056	0.0183	0.0698
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Loa Loa (eye worm)	PAN domain-containing protein	0.0014	0.002	0.0078
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0048	0.0152	1
Schistosoma mansoni	neuropeptide receptor	0.0056	0.0183	0.0698
Echinococcus granulosus	dro:myosuppressin receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0056	0.0183	0.0698
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0056	0.0183	0.0183
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.0183	0.0698
Toxoplasma gondii	microneme protein MIC17A	0.0014	0.002	0.003
Brugia malayi	cathepsin B-like cysteine proteinase	0.0146	0.0528	0.1992
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0056	0.0183	0.0183
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.0183	0.0698
Trypanosoma cruzi	prolyl endopeptidase	0.0127	0.0455	0.8609
Toxoplasma gondii	PAN/Apple domain-containing protein	0.0014	0.002	0.003
Echinococcus multilocularis	neuropeptides capa receptor	0.0056	0.0183	0.0183
Brugia malayi	Dopamine receptor	0.0056	0.0183	0.0645
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0056	0.0183	0.0698
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0056	0.0183	0.0698
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0183	0.071
Brugia malayi	PAN domain containing protein	0.0014	0.002	0.0009
Entamoeba histolytica	hypothetical protein, conserved	0.0013	0.0018	0.3884
Echinococcus granulosus	rhodopsin orphan GPCR	0.0056	0.0183	0.0183

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 900983