Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cathepsin F (C01 family) | 0.0079 | 0.185 | 0.185 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0116 | 0.5815 | 1 |
Onchocerca volvulus | 0.0116 | 0.5815 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.5815 | 0.5661 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0116 | 0.5815 | 1 |
Plasmodium vivax | vivapain-2 | 0.0116 | 0.5815 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0079 | 0.185 | 0.185 |
Loa Loa (eye worm) | fibroinase | 0.0116 | 0.5815 | 0.5661 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0116 | 0.5815 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0065 | 0.0354 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0116 | 0.5815 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0116 | 0.5815 | 0.5815 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0116 | 0.5815 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0116 | 0.5815 | 0.5815 |
Onchocerca volvulus | 0.0116 | 0.5815 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0116 | 0.5815 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0079 | 0.185 | 0.3182 |
Echinococcus multilocularis | cysteine protease | 0.0116 | 0.5815 | 0.5815 |
Leishmania major | cathepsin L-like protease | 0.0116 | 0.5815 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0116 | 0.5815 | 0.5815 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0116 | 0.5815 | 0.5815 |
Brugia malayi | Cathepsin L-like precursor | 0.0079 | 0.185 | 0.185 |
Brugia malayi | Cathepsin L-like precursor | 0.0116 | 0.5815 | 0.5815 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0155 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0079 | 0.185 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0079 | 0.185 | 0.185 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0116 | 0.5815 | 0.5815 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0116 | 0.5815 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0116 | 0.5815 | 0.5815 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Onchocerca volvulus | 0.0116 | 0.5815 | 1 | |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0155 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0155 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0116 | 0.5815 | 0.5815 |
Echinococcus granulosus | cathepsin b | 0.0155 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0155 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0155 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0155 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0116 | 0.5815 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0116 | 0.5815 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0155 | 1 | 1 |
Onchocerca volvulus | 0.0116 | 0.5815 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0116 | 0.5815 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0116 | 0.5815 | 0.5815 |
Leishmania major | cysteine peptidase A (CPA) | 0.0116 | 0.5815 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0065 | 0.0354 | 0.0354 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0065 | 0.0354 | 0.0354 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Leishmania major | cathepsin L-like protease | 0.0116 | 0.5815 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0116 | 0.5815 | 0.5815 |
Loa Loa (eye worm) | ctsf protein | 0.0116 | 0.5815 | 0.5661 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0116 | 0.5815 | 0.5815 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0116 | 0.5815 | 0.5815 |
Brugia malayi | Cathepsin L-like precursor | 0.0079 | 0.185 | 0.185 |
Onchocerca volvulus | 0.0116 | 0.5815 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0116 | 0.5815 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0116 | 0.5815 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0116 | 0.5815 | 0.5815 |
Leishmania major | cathepsin L-like protease | 0.0116 | 0.5815 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0079 | 0.185 | 0.185 |
Echinococcus granulosus | cathepsin b | 0.0155 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Onchocerca volvulus | 0.0116 | 0.5815 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0116 | 0.5815 | 1 |
Plasmodium vivax | vivapain-2 | 0.0116 | 0.5815 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0116 | 0.5815 | 0.5661 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0116 | 0.5815 | 0.5815 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0116 | 0.5815 | 0.5815 |
Leishmania major | cathepsin L-like protease | 0.0116 | 0.5815 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0116 | 0.5815 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0116 | 0.5815 | 0.5661 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.185 | 0.1551 |
Giardia lamblia | Cathepsin B precursor | 0.0065 | 0.0354 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0116 | 0.5815 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.185 | 0.1551 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0116 | 0.5815 | 1 |
Leishmania major | cathepsin L-like protease | 0.0116 | 0.5815 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0116 | 0.5815 | 0.5815 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0079 | 0.185 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0116 | 0.5815 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0116 | 0.5815 | 0.5661 |
Onchocerca volvulus | 0.0116 | 0.5815 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0116 | 0.5815 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0079 | 0.185 | 0.185 |
Brugia malayi | Cathepsin L-like precursor | 0.0116 | 0.5815 | 0.5815 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0116 | 0.5815 | 0.5815 |
Onchocerca volvulus | Cathepsin F homolog | 0.0116 | 0.5815 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0116 | 0.5815 | 0.5815 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.185 | 0.1551 |
Leishmania major | cathepsin L-like protease | 0.0116 | 0.5815 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0116 | 0.5815 | 1 |
Leishmania major | cathepsin L-like protease | 0.0116 | 0.5815 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0116 | 0.5815 | 0.5815 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0116 | 0.5815 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0065 | 0.0354 | 0.0609 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0065 | 0.0354 | 0.0609 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0116 | 0.5815 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0116 | 0.5815 | 0.5815 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0116 | 0.5815 | 0.5815 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0065 | 0.0354 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.5815 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.